AutismKB 2.0

Annotation Detail for SOAT1


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Basic Information Top
Gene Symbol:SOAT1 ( ACACT,ACAT,ACAT1,RP11-215I23.2,SOAT,STAT )
Gene Full Name: sterol O-acyltransferase 1
Band: 1q25.2
Quick LinksEntrez ID:6646; OMIM: 102642; Uniprot ID:SOAT1_HUMAN; ENSEMBL ID: ENSG00000057252; HGNC ID: 11177
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus21 / 56401237
neonate10 / 31097321
infant0 / 236200 
juvenile3 / 5555653
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor23 / 26384587
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal147 / 336030743
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer15 / 102680146
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland15 / 33197451
ascites1 / 4001524
bladder3 / 29757100
blood7 / 12347856
bone4 / 7165555
bone marrow3 / 4880161
brain38 / 110098934
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine6 / 23447225
kidney18 / 21177784
larynx0 / 241450 
liver8 / 20774338
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth2 / 6705229
muscle8 / 10771574
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta11 / 28082539
prostate20 / 189345105
salivary gland0 / 201550 
skin15 / 21057471
spleen2 / 5395237
stomach2 / 9661920
testis20 / 33044260
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea18 / 52413343
umbilical cord0 / 136800 
uterus12 / 23287851
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221561_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.1
Adipocyte18.75
AdrenalCortex80.15
Adrenalgland194.15
Amygdala9.95
Appendix18.1
AtrioventricularNode16.6
BDCA4+_DentriticCells10.6
Bonemarrow13.6
BronchialEpithelialCells9.9
CD105+_Endothelial10.45
CD14+_Monocytes13.3
CD19+_BCells(neg._sel.)10.65
CD33+_Myeloid17.15
CD34+12.4
CD4+_Tcells9.85
CD56+_NKCells11.3
CD71+_EarlyErythroid10.4
CD8+_Tcells9.45
CardiacMyocytes22.35
Caudatenucleus9.65
Cerebellum8.7
CerebellumPeduncles13.75
CiliaryGanglion13.95
CingulateCortex11.45
Colorectaladenocarcinoma10.55
DorsalRootGanglion11.95
FetalThyroid11
Fetalbrain9.7
Fetalliver9.4
Fetallung7.75
GlobusPallidus9.45
Heart22.75
Hypothalamus10.5
Kidney10.7
Leukemia_chronicMyelogenousK-5629.4
Leukemia_promyelocytic-HL-609.55
Leukemialymphoblastic(MOLT-4)7.8
Liver18.65
Lung16.6
Lymphnode9.2
Lymphoma_burkitts(Daudi)14.75
Lymphoma_burkitts(Raji)18.05
MedullaOblongata9.3
OccipitalLobe9.35
OlfactoryBulb8.15
Ovary9.6
Pancreas9.55
PancreaticIslet12
ParietalLobe12.35
Pituitary12.75
Placenta10.7
Pons11
PrefrontalCortex11.5
Prostate27.8
Salivarygland15.95
SkeletalMuscle18.45
Skin13.9
SmoothMuscle12.8
Spinalcord11.05
SubthalamicNucleus11
SuperiorCervicalGanglion27.9
TemporalLobe10.2
Testis9.05
TestisGermCell8.3
TestisIntersitial9.3
TestisLeydigCell11.8
TestisSeminiferousTubule8.9
Thalamus11.25
Thymus7.55
Thyroid13.35
Tongue13.9
Tonsil10.85
Trachea8.8
TrigeminalGanglion18.65
Uterus8.15
UterusCorpus12.75
WholeBlood34.75
Wholebrain7.9
colon13.75
pineal_day12.42
pineal_night12.42
retina13.275
small_intestine11.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P63319
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.71 ± 0.55
Basal Forebrain3.51 ± 0.44
Basal Part of Pons3.64 ± 0.6
Cerebellar Cortex3.38 ± 0.46
Cerebellar Nuclei4.14 ± 0.52
Claustrum3.58 ± 0.52
Epithalamus4.18 ± 0.38
Frontal Lobe3.57 ± 0.6
Globus Pallidus4.55 ± 0.51
Hypothalamus3.69 ± 0.43
Insula3.64 ± 0.37
Limbic Lobe3.43 ± 0.58
Mesencephalon3.75 ± 0.54
Myelencephalon3.64 ± 0.58
Occipital Lobe3.68 ± 0.61
Parietal Lobe3.63 ± 0.49
Pontine Tegmentum3.64 ± 0.62
Striatum4.17 ± 0.43
Subthalamus3.86 ± 0.11
Temporal Lobe3.44 ± 0.56
Thalamus3.49 ± 0.53
White Matter4.41 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Soat1CBCerebellum17.56
24.25
Soat1CTXCerebral cortex20.38
14.31
Soat1HIPHippocampal region19.21
21.91
Soat1HPFHippocampal formation21.56
20.57
Soat1HYHypothalamus1.99
1.88
Soat1LSXLateral septal complex3.12
2.17
Soat1MBMidbrain5.48
5.5
Soat1MYMedulla10.46
12.69
Soat1OLFOlfactory bulb21.44
16.84
Soat1PPons4.4
5.71
Soat1PALPallidum6.07
5.5
Soat1RHPRetrohippocampal region25.03
19.17
Soat1sAMYStriatum-like amygdalar nuclei10.84
7.38
Soat1STRStriatum7.48
5.17
Soat1STRdStriatum dorsal region8.01
5.54
Soat1STRvStriatum ventral region5.18
3.83
Soat1THThalamus12.66
10.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00006956 21 84 104 SASLDNGGCALTTFSVLEGEK Peptide Atlas
SOAT1_HUMAN_1 10 1 10 MVGEEKMSLR PRIDE
SOAT1_HUMAN_54 14 54 67 LTAEAEELKPFFMK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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