AutismKB 2.0

Annotation Detail for SOD2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SOD2 ( IPOB,MNSOD,MVCD6 )
Gene Full Name: superoxide dismutase 2, mitochondrial
Band: 6q25.3
Quick LinksEntrez ID:6648; OMIM: 147460; Uniprot ID:SODM_HUMAN; ENSEMBL ID: ENSG00000112096; HGNC ID: 11180
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus70 / 564012124
neonate10 / 31097321
infant6 / 23620254
juvenile8 / 55556143
adult442 / 1939121227
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor2 / 9417821
cervical tumor9 / 34366261
chondrosarcoma36 / 82823434
colorectal tumor13 / 114246113
esophageal tumor3 / 17290173
gastrointestinal tumor28 / 119369234
germ cell tumor16 / 26384560
glioma40 / 106883374
head and neck tumor34 / 136302249
kidney tumor13 / 68959188
leukemia13 / 95842135
liver tumor21 / 96359217
lung tumor19 / 103127184
lymphoma8 / 71755111
non-neoplasia39 / 97250401
normal566 / 3360307168
ovarian tumor3 / 7668239
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer10 / 10268097
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor17 / 125191135
uterine tumor19 / 90257210
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland0 / 331970 
ascites1 / 4001524
bladder16 / 29757537
blood52 / 123478421
bone25 / 71655348
bone marrow6 / 48801122
brain190 / 1100989172
cervix9 / 48171186
connective tissue69 / 149255462
ear5 / 16212308
embryonic tissue9 / 21572241
esophagus3 / 20209148
eye19 / 21105490
heart13 / 89626145
intestine24 / 234472102
kidney47 / 211777221
larynx2 / 2414582
liver81 / 207743389
lung114 / 336974338
lymph6 / 44270135
lymph node4 / 9161043
mammary gland16 / 153271104
mouth25 / 67052372
muscle39 / 107715362
nerve3 / 15768190
ovary3 / 10205129
pancreas35 / 214812162
parathyroid7 / 20539340
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta18 / 28082564
prostate22 / 189345116
salivary gland8 / 20155396
skin14 / 21057466
spleen2 / 5395237
stomach38 / 96619393
testis26 / 33044278
thymus29 / 81131357
thyroid8 / 47473168
tonsil2 / 16999117
trachea49 / 52413934
umbilical cord0 / 136800 
uterus93 / 232878399
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215223_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.95
Adipocyte61.65
AdrenalCortex10.2
Adrenalgland7.85
Amygdala8.6
Appendix8.8
AtrioventricularNode7.3
BDCA4+_DentriticCells50.2
Bonemarrow31.5
BronchialEpithelialCells9.75
CD105+_Endothelial12.85
CD14+_Monocytes160
CD19+_BCells(neg._sel.)31.6
CD33+_Myeloid271.5
CD34+33.2
CD4+_Tcells8.6
CD56+_NKCells36.8
CD71+_EarlyErythroid18.1
CD8+_Tcells7.25
CardiacMyocytes13.05
Caudatenucleus6.2
Cerebellum6.85
CerebellumPeduncles9.5
CiliaryGanglion7.85
CingulateCortex8.6
Colorectaladenocarcinoma8.45
DorsalRootGanglion7.1
FetalThyroid8.4
Fetalbrain45.55
Fetalliver7.4
Fetallung270.55
GlobusPallidus6.1
Heart22.4
Hypothalamus8.45
Kidney7.65
Leukemia_chronicMyelogenousK-5627.55
Leukemia_promyelocytic-HL-6014.75
Leukemialymphoblastic(MOLT-4)6.35
Liver12.4
Lung33.45
Lymphnode10.45
Lymphoma_burkitts(Daudi)11.45
Lymphoma_burkitts(Raji)13
MedullaOblongata5.85
OccipitalLobe6.7
OlfactoryBulb5.95
Ovary7.4
Pancreas22.6
PancreaticIslet843.5
ParietalLobe8.45
Pituitary10.35
Placenta8.6
Pons21.1
PrefrontalCortex8.75
Prostate18.75
Salivarygland15.65
SkeletalMuscle86.9
Skin9.5
SmoothMuscle731.5
Spinalcord8.2
SubthalamicNucleus7.8
SuperiorCervicalGanglion9.75
TemporalLobe7.3
Testis13.1
TestisGermCell9.1
TestisIntersitial11.85
TestisLeydigCell8.7
TestisSeminiferousTubule7.25
Thalamus8.35
Thymus6.75
Thyroid10.4
Tongue9.05
Tonsil9.5
Trachea9.35
TrigeminalGanglion11.25
Uterus11.25
UterusCorpus70
WholeBlood1337.55
Wholebrain6.75
colon8.55
pineal_day9.12
pineal_night9.38
retina23.7
small_intestine7.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P134176
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.1 ± 0.23
Basal Forebrain10.1 ± 0.15
Basal Part of Pons10.45 ± 0.25
Cerebellar Cortex9.94 ± 0.23
Cerebellar Nuclei10.7 ± 0.34
Claustrum10.19 ± 0.37
Epithalamus10.53 ± 0.28
Frontal Lobe10.31 ± 0.45
Globus Pallidus10.54 ± 0.36
Hypothalamus10.37 ± 0.29
Insula10.18 ± 0.24
Limbic Lobe10.16 ± 0.41
Mesencephalon10.38 ± 0.41
Myelencephalon10.23 ± 0.33
Occipital Lobe10.21 ± 0.28
Parietal Lobe10.37 ± 0.32
Pontine Tegmentum10.21 ± 0.33
Striatum10.19 ± 0.36
Subthalamus10.82 ± 0.12
Temporal Lobe10.17 ± 0.28
Thalamus10.3 ± 0.27
White Matter9.57 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sod2CBCerebellum0
0
Sod2CTXCerebral cortex0
0
Sod2HIPHippocampal region0
0
Sod2HPFHippocampal formation0
0
Sod2HYHypothalamus0
0
Sod2LSXLateral septal complex0
0
Sod2MBMidbrain0
0
Sod2MYMedulla0
0
Sod2OLFOlfactory bulb0
0
Sod2PPons0
0
Sod2PALPallidum0
0
Sod2RHPRetrohippocampal region0
0
Sod2sAMYStriatum-like amygdalar nuclei0
0
Sod2STRStriatum0
0
Sod2STRdStriatum dorsal region0
0
Sod2STRvStriatum ventral region0
0
Sod2THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000458 14 203 216 AIWNVINWENVTER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved