AutismKB 2.0

Annotation Detail for BNIP3L


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Basic Information Top
Gene Symbol:BNIP3L ( BNIP3a,NIX )
Gene Full Name: BCL2/adenovirus E1B 19kDa interacting protein 3-like
Band: 8p21.2
Quick LinksEntrez ID:665; OMIM: 605368; Uniprot ID:BNI3L_HUMAN; ENSEMBL ID: ENSG00000104765; HGNC ID: 1085
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst3 / 6231948
fetus76 / 564012134
neonate4 / 31097128
infant2 / 2362084
juvenile5 / 5555689
adult187 / 193912196
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor8 / 9417884
cervical tumor2 / 3436658
chondrosarcoma19 / 82823229
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor20 / 26384575
glioma11 / 106883102
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia13 / 95842135
liver tumor7 / 9635972
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia11 / 97250113
normal589 / 3360307175
ovarian tumor5 / 7668265
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor11 / 12494988
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood148 / 1234781198
bone16 / 71655223
bone marrow14 / 48801286
brain196 / 1100989178
cervix2 / 4817141
connective tissue16 / 149255107
ear3 / 16212185
embryonic tissue28 / 215722129
esophagus1 / 2020949
eye26 / 211054123
heart5 / 8962655
intestine14 / 23447259
kidney22 / 211777103
larynx1 / 2414541
liver27 / 207743129
lung27 / 33697480
lymph1 / 4427022
lymph node9 / 9161098
mammary gland18 / 153271117
mouth6 / 6705289
muscle21 / 107715194
nerve1 / 1576863
ovary6 / 10205158
pancreas22 / 214812102
parathyroid4 / 20539194
pharynx7 / 41328169
pituitary gland1 / 1658560
placenta29 / 280825103
prostate5 / 18934526
salivary gland1 / 2015549
skin19 / 21057490
spleen1 / 5395218
stomach1 / 9661910
testis74 / 330442223
thymus7 / 8113186
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus23 / 23287898
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221478_at
Cell line Expression level Expression bar
721_B_lymphoblasts628.75
Adipocyte424.45
AdrenalCortex22.55
Adrenalgland39.9
Amygdala431
Appendix54.15
AtrioventricularNode17.4
BDCA4+_DentriticCells194.65
Bonemarrow123.1
BronchialEpithelialCells128.95
CD105+_Endothelial579.8
CD14+_Monocytes541.75
CD19+_BCells(neg._sel.)291.05
CD33+_Myeloid625.65
CD34+296.8
CD4+_Tcells84.75
CD56+_NKCells152
CD71+_EarlyErythroid3606.6
CD8+_Tcells75.15
CardiacMyocytes353.2
Caudatenucleus157
Cerebellum34.3
CerebellumPeduncles115.85
CiliaryGanglion40.75
CingulateCortex165.9
Colorectaladenocarcinoma79.5
DorsalRootGanglion21.1
FetalThyroid92.55
Fetalbrain465.2
Fetalliver582.5
Fetallung386.4
GlobusPallidus166.35
Heart13.35
Hypothalamus402.65
Kidney12.1
Leukemia_chronicMyelogenousK-56271.45
Leukemia_promyelocytic-HL-60185.85
Leukemialymphoblastic(MOLT-4)180.75
Liver10.1
Lung10.95
Lymphnode83.2
Lymphoma_burkitts(Daudi)36.8
Lymphoma_burkitts(Raji)119.2
MedullaOblongata244.85
OccipitalLobe370.75
OlfactoryBulb118.3
Ovary335.8
Pancreas18.65
PancreaticIslet168.6
ParietalLobe224.65
Pituitary137.9
Placenta121.8
Pons76.45
PrefrontalCortex418.45
Prostate151.05
Salivarygland31.65
SkeletalMuscle14.95
Skin44.75
SmoothMuscle978.95
Spinalcord257.1
SubthalamicNucleus148.8
SuperiorCervicalGanglion46.25
TemporalLobe116.85
Testis27.05
TestisGermCell256
TestisIntersitial56
TestisLeydigCell26.7
TestisSeminiferousTubule80.35
Thalamus215
Thymus17.75
Thyroid226.9
Tongue19.75
Tonsil46.05
Trachea87.15
TrigeminalGanglion13.1
Uterus259.15
UterusCorpus114.3
WholeBlood513.45
Wholebrain186.05
colon103.95
pineal_day453.48
pineal_night532
retina208.625
small_intestine52.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P408708
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.06 ± 0.26
Basal Forebrain10.09 ± 0.14
Basal Part of Pons10.47 ± 0.13
Cerebellar Cortex10.16 ± 0.16
Cerebellar Nuclei10.63 ± 0.2
Claustrum10.18 ± 0.25
Epithalamus10.49 ± 0.11
Frontal Lobe10.37 ± 0.27
Globus Pallidus10.57 ± 0.21
Hypothalamus10.23 ± 0.17
Insula10.22 ± 0.18
Limbic Lobe10.36 ± 0.34
Mesencephalon10.35 ± 0.32
Myelencephalon10.28 ± 0.29
Occipital Lobe10.51 ± 0.25
Parietal Lobe10.36 ± 0.27
Pontine Tegmentum10.31 ± 0.25
Striatum9.97 ± 0.32
Subthalamus10.71 ± 0.26
Temporal Lobe10.31 ± 0.23
Thalamus10.29 ± 0.17
White Matter11.21 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bnip3lCBCerebellum7.2
7.71
Bnip3lCTXCerebral cortex7.36
6.6
Bnip3lHIPHippocampal region11.74
13.58
Bnip3lHPFHippocampal formation10.68
11.38
Bnip3lHYHypothalamus0.37
0.51
Bnip3lLSXLateral septal complex0.58
0.57
Bnip3lMBMidbrain2.47
3.41
Bnip3lMYMedulla3.5
4.59
Bnip3lOLFOlfactory bulb10.21
10.24
Bnip3lPPons2.51
3.13
Bnip3lPALPallidum0.46
0.43
Bnip3lRHPRetrohippocampal region9.08
8.57
Bnip3lsAMYStriatum-like amygdalar nuclei0.44
0.57
Bnip3lSTRStriatum0.96
1.16
Bnip3lSTRdStriatum dorsal region0.85
1.13
Bnip3lSTRvStriatum ventral region1.72
1.61
Bnip3lTHThalamus3.81
5.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00513408 15 115 129 DHSSQSEEEVVEGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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