AutismKB 2.0

Annotation Detail for SOX4


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Basic Information Top
Gene Symbol:SOX4 ( EVI16 )
Gene Full Name: SRY (sex determining region Y)-box 4
Band: 6p22.3
Quick LinksEntrez ID:6659; OMIM: 184430; Uniprot ID:SOX4_HUMAN; ENSEMBL ID: ENSG00000124766; HGNC ID: 11200
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body20 / 70761282
blastocyst12 / 62319192
fetus184 / 564012326
neonate0 / 310970 
infant0 / 236200 
juvenile7 / 55556125
adult138 / 193912171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor51 / 263845193
glioma41 / 106883383
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor12 / 103127116
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal475 / 3360307141
ovarian tumor20 / 76682260
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer15 / 102680146
retinoblastoma0 / 463560 
skin tumor12 / 12494996
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites5 / 40015124
bladder4 / 29757134
blood20 / 123478161
bone3 / 7165541
bone marrow46 / 48801942
brain63 / 110098957
cervix0 / 481710 
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue46 / 215722213
esophagus0 / 202090 
eye29 / 211054137
heart23 / 89626256
intestine27 / 234472115
kidney19 / 21177789
larynx3 / 24145124
liver73 / 207743351
lung73 / 336974216
lymph0 / 442700 
lymph node3 / 9161032
mammary gland24 / 153271156
mouth2 / 6705229
muscle3 / 10771527
nerve2 / 15768126
ovary22 / 102051215
pancreas13 / 21481260
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland5 / 16585301
placenta3 / 28082510
prostate30 / 189345158
salivary gland0 / 201550 
skin20 / 21057494
spleen1 / 5395218
stomach11 / 96619113
testis8 / 33044224
thymus9 / 81131110
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus20 / 23287885
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213668_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.25
Adipocyte4.85
AdrenalCortex5.6
Adrenalgland4.25
Amygdala5
Appendix5.25
AtrioventricularNode3.85
BDCA4+_DentriticCells64.75
Bonemarrow5.2
BronchialEpithelialCells4.9
CD105+_Endothelial5
CD14+_Monocytes5.2
CD19+_BCells(neg._sel.)5
CD33+_Myeloid6.3
CD34+96.65
CD4+_Tcells5.2
CD56+_NKCells5.6
CD71+_EarlyErythroid4.55
CD8+_Tcells4.35
CardiacMyocytes6.8
Caudatenucleus4.4
Cerebellum4
CerebellumPeduncles5.65
CiliaryGanglion3.6
CingulateCortex5.05
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.8
FetalThyroid5.5
Fetalbrain8.8
Fetalliver4.35
Fetallung5.85
GlobusPallidus3.6
Heart6.85
Hypothalamus4.95
Kidney4.35
Leukemia_chronicMyelogenousK-5624.45
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)136.15
Liver6.95
Lung5.5
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)6.95
MedullaOblongata4.45
OccipitalLobe4.25
OlfactoryBulb3.75
Ovary3.4
Pancreas4.1
PancreaticIslet5.25
ParietalLobe5.2
Pituitary5.75
Placenta5
Pons4.75
PrefrontalCortex5.6
Prostate9.6
Salivarygland3.9
SkeletalMuscle5.8
Skin3.9
SmoothMuscle5.65
Spinalcord5.1
SubthalamicNucleus4.45
SuperiorCervicalGanglion5.85
TemporalLobe4.55
Testis4.25
TestisGermCell4.05
TestisIntersitial4.15
TestisLeydigCell4.9
TestisSeminiferousTubule4.25
Thalamus5
Thymus51.9
Thyroid6.3
Tongue4.9
Tonsil4.8
Trachea4.15
TrigeminalGanglion5.5
Uterus4.1
UterusCorpus7.7
WholeBlood5.35
Wholebrain4.15
colon4.95
pineal_day6
pineal_night5.84
retina5.875
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P82169
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.4 ± 0.43
Basal Forebrain9.41 ± 0.17
Basal Part of Pons9.15 ± 0.35
Cerebellar Cortex9.59 ± 0.27
Cerebellar Nuclei9.15 ± 0.29
Claustrum9.47 ± 0.37
Epithalamus9.6 ± 0.38
Frontal Lobe9.12 ± 0.4
Globus Pallidus9 ± 0.26
Hypothalamus9.45 ± 0.38
Insula9.38 ± 0.25
Limbic Lobe9.13 ± 0.42
Mesencephalon9.23 ± 0.37
Myelencephalon9.25 ± 0.35
Occipital Lobe9.46 ± 0.43
Parietal Lobe9.03 ± 0.32
Pontine Tegmentum9.06 ± 0.42
Striatum8.92 ± 0.32
Subthalamus8.58 ± 0.33
Temporal Lobe9.35 ± 0.29
Thalamus9.2 ± 0.29
White Matter9.36 ± 0.31
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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