AutismKB 2.0

Annotation Detail for SOX5


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Basic Information Top
Gene Symbol:SOX5 ( L-SOX5,MGC35153 )
Gene Full Name: SRY (sex determining region Y)-box 5
Band: 12p12.1
Quick LinksEntrez ID:6660; OMIM: 604975; Uniprot ID:SOX5_HUMAN; ENSEMBL ID: ENSG00000134532; HGNC ID: 11201
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal65 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain41 / 110098937
cervix0 / 481710 
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver3 / 20774314
lung11 / 33697432
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207336_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4.1
AdrenalCortex4.5
Adrenalgland3.55
Amygdala4.3
Appendix4.35
AtrioventricularNode3.25
BDCA4+_DentriticCells4.5
Bonemarrow4.2
BronchialEpithelialCells4.05
CD105+_Endothelial4.15
CD14+_Monocytes4.4
CD19+_BCells(neg._sel.)4.45
CD33+_Myeloid5.35
CD34+5.3
CD4+_Tcells4.5
CD56+_NKCells5
CD71+_EarlyErythroid3.9
CD8+_Tcells4.05
CardiacMyocytes5.5
Caudatenucleus3.75
Cerebellum3.35
CerebellumPeduncles4.75
CiliaryGanglion3
CingulateCortex4.25
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.25
FetalThyroid4.05
Fetalbrain4.2
Fetalliver3.6
Fetallung3.45
GlobusPallidus3.15
Heart5.6
Hypothalamus4.45
Kidney3.45
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.35
Liver5.6
Lung4.55
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.35
Lymphoma_burkitts(Raji)5.9
MedullaOblongata3.8
OccipitalLobe3.75
OlfactoryBulb3.3
Ovary2.8
Pancreas3.35
PancreaticIslet4.45
ParietalLobe4.45
Pituitary4.85
Placenta4.3
Pons4
PrefrontalCortex5.35
Prostate4.9
Salivarygland3.4
SkeletalMuscle5.05
Skin3.3
SmoothMuscle4.7
Spinalcord4.4
SubthalamicNucleus3.85
SuperiorCervicalGanglion5.2
TemporalLobe3.85
Testis16.15
TestisGermCell22.6
TestisIntersitial22.6
TestisLeydigCell13.55
TestisSeminiferousTubule6.25
Thalamus4.2
Thymus3.25
Thyroid5.2
Tongue4.2
Tonsil4.05
Trachea3.5
TrigeminalGanglion4.55
Uterus3.45
UterusCorpus4.05
WholeBlood4.55
Wholebrain3.5
colon4.15
pineal_day5.24
pineal_night5.1
retina5.05
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P925186
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.73 ± 0.76
Basal Forebrain4.49 ± 0.34
Basal Part of Pons5 ± 0.37
Cerebellar Cortex3.85 ± 0.47
Cerebellar Nuclei3.96 ± 0.59
Claustrum5.31 ± 0.37
Epithalamus4.73 ± 0.44
Frontal Lobe4.79 ± 0.53
Globus Pallidus4.71 ± 0.58
Hypothalamus4.65 ± 0.71
Insula4.91 ± 0.52
Limbic Lobe4.48 ± 0.61
Mesencephalon4.45 ± 0.72
Myelencephalon4.46 ± 0.64
Occipital Lobe4.18 ± 0.6
Parietal Lobe4.42 ± 0.51
Pontine Tegmentum4.49 ± 0.59
Striatum4.07 ± 0.88
Subthalamus4.38 ± 0.11
Temporal Lobe4.63 ± 0.48
Thalamus4.54 ± 0.44
White Matter3.37 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sox5CBCerebellum11.3
13.12
Sox5CTXCerebral cortex19.68
12.71
Sox5HIPHippocampal region21.7
15.25
Sox5HPFHippocampal formation19.4
13.68
Sox5HYHypothalamus4.21
2.79
Sox5LSXLateral septal complex1.75
1.39
Sox5MBMidbrain3.63
2.79
Sox5MYMedulla12.01
10.8
Sox5OLFOlfactory bulb23.93
15.31
Sox5PPons8.63
7.77
Sox5PALPallidum1.92
1.17
Sox5RHPRetrohippocampal region16.8
11.96
Sox5sAMYStriatum-like amygdalar nuclei5.66
3.45
Sox5STRStriatum1.79
1.13
Sox5STRdStriatum dorsal region0.93
0.6
Sox5STRvStriatum ventral region2.27
1.14
Sox5THThalamus6.45
4.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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