AutismKB 2.0

Annotation Detail for SOX10


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Basic Information Top
Gene Symbol:SOX10 ( DOM,MGC15649,PCWH,WS2E,WS4,WS4C )
Gene Full Name: SRY (sex determining region Y)-box 10
Band: 22q13.1
Quick LinksEntrez ID:6663; OMIM: 602229; Uniprot ID:SOX10_HUMAN; ENSEMBL ID: ENSG00000100146; HGNC ID: 11190
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma14 / 106883130
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor106 / 124949848
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain32 / 110098929
cervix0 / 481710 
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland12 / 15327178
mouth0 / 670520 
muscle0 / 1077150 
nerve4 / 15768253
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate1 / 1893455
salivary gland0 / 201550 
skin110 / 210574522
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209843_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.15
Adipocyte7.05
AdrenalCortex7.6
Adrenalgland12.25
Amygdala7.4
Appendix6.7
AtrioventricularNode13.05
BDCA4+_DentriticCells6.95
Bonemarrow10.15
BronchialEpithelialCells5.55
CD105+_Endothelial6.5
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid8.3
CD34+8.15
CD4+_Tcells6.9
CD56+_NKCells7.25
CD71+_EarlyErythroid7.1
CD8+_Tcells5.7
CardiacMyocytes9.45
Caudatenucleus16.1
Cerebellum8.95
CerebellumPeduncles20
CiliaryGanglion4.75
CingulateCortex21.5
Colorectaladenocarcinoma6.15
DorsalRootGanglion13.85
FetalThyroid9.4
Fetalbrain6.75
Fetalliver5.85
Fetallung5.15
GlobusPallidus6.5
Heart11.45
Hypothalamus10.05
Kidney9.15
Leukemia_chronicMyelogenousK-5628.6
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)5.4
Liver8.45
Lung6.4
Lymphnode10.75
Lymphoma_burkitts(Daudi)10.05
Lymphoma_burkitts(Raji)8.05
MedullaOblongata22.35
OccipitalLobe31.4
OlfactoryBulb31.95
Ovary4.45
Pancreas5.4
PancreaticIslet7.25
ParietalLobe30.45
Pituitary8.85
Placenta6.9
Pons22.8
PrefrontalCortex11.5
Prostate7.65
Salivarygland9.15
SkeletalMuscle13.4
Skin5.5
SmoothMuscle7.85
Spinalcord23.95
SubthalamicNucleus6.65
SuperiorCervicalGanglion8.05
TemporalLobe7.95
Testis7.3
TestisGermCell5.15
TestisIntersitial5.65
TestisLeydigCell6.75
TestisSeminiferousTubule8.15
Thalamus25.45
Thymus5.45
Thyroid7.7
Tongue6.65
Tonsil13.2
Trachea15.9
TrigeminalGanglion9.5
Uterus4.2
UterusCorpus5.9
WholeBlood7.4
Wholebrain10.75
colon6.8
pineal_day7.24
pineal_night7.94
retina24.975
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P143694
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.96 ± 0.57
Basal Forebrain4.63 ± 0.91
Basal Part of Pons4.57 ± 0.97
Cerebellar Cortex3.83 ± 0.63
Cerebellar Nuclei5.09 ± 0.76
Claustrum3.73 ± 0.81
Epithalamus3.95 ± 0.99
Frontal Lobe4.46 ± 0.97
Globus Pallidus5.73 ± 0.36
Hypothalamus3.81 ± 0.33
Insula4 ± 0.63
Limbic Lobe4.04 ± 0.76
Mesencephalon4.33 ± 0.98
Myelencephalon4.48 ± 0.81
Occipital Lobe4.26 ± 0.72
Parietal Lobe4.23 ± 0.82
Pontine Tegmentum4.48 ± 0.81
Striatum5.22 ± 0.65
Subthalamus4.48 ± 0.69
Temporal Lobe4.26 ± 0.7
Thalamus4.99 ± 0.71
White Matter7.21 ± 0.34
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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