AutismKB 2.0

Annotation Detail for SP1


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Basic Information Top
Gene Symbol:SP1 ( - )
Gene Full Name: Sp1 transcription factor
Band: 12q13.13
Quick LinksEntrez ID:6667; OMIM: 189906; Uniprot ID:SP1_HUMAN; ENSEMBL ID: ENSG00000185591; HGNC ID: 11205
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst11 / 62319176
fetus57 / 564012101
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult137 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor18 / 114246157
esophageal tumor2 / 17290115
gastrointestinal tumor9 / 11936975
germ cell tumor18 / 26384568
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal242 / 336030772
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood7 / 12347856
bone2 / 7165527
bone marrow0 / 488010 
brain35 / 110098931
cervix3 / 4817162
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue31 / 215722143
esophagus2 / 2020998
eye15 / 21105471
heart10 / 89626111
intestine25 / 234472106
kidney17 / 21177780
larynx1 / 2414541
liver7 / 20774333
lung20 / 33697459
lymph0 / 442700 
lymph node18 / 91610196
mammary gland14 / 15327191
mouth5 / 6705274
muscle7 / 10771564
nerve1 / 1576863
ovary5 / 10205148
pancreas18 / 21481283
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta16 / 28082556
prostate12 / 18934563
salivary gland0 / 201550 
skin15 / 21057471
spleen2 / 5395237
stomach5 / 9661951
testis17 / 33044251
thymus2 / 8113124
thyroid4 / 4747384
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus17 / 23287872
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214732_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.85
AdrenalCortex7.55
Adrenalgland5.85
Amygdala7.05
Appendix7.55
AtrioventricularNode6.55
BDCA4+_DentriticCells7.15
Bonemarrow7.2
BronchialEpithelialCells6.45
CD105+_Endothelial6.65
CD14+_Monocytes7.2
CD19+_BCells(neg._sel.)7.05
CD33+_Myeloid8.9
CD34+8.2
CD4+_Tcells7.5
CD56+_NKCells8.3
CD71+_EarlyErythroid8.8
CD8+_Tcells6.4
CardiacMyocytes9.05
Caudatenucleus6.25
Cerebellum5.65
CerebellumPeduncles7.9
CiliaryGanglion5.95
CingulateCortex7.15
Colorectaladenocarcinoma6.95
DorsalRootGanglion5.7
FetalThyroid6.75
Fetalbrain6.75
Fetalliver6.1
Fetallung5.5
GlobusPallidus5.3
Heart8.9
Hypothalamus7.5
Kidney5.85
Leukemia_chronicMyelogenousK-5626.15
Leukemia_promyelocytic-HL-606.05
Leukemialymphoblastic(MOLT-4)5.55
Liver9.45
Lung7.4
Lymphnode5.9
Lymphoma_burkitts(Daudi)8.95
Lymphoma_burkitts(Raji)9.8
MedullaOblongata6.3
OccipitalLobe6.2
OlfactoryBulb5.45
Ovary4.9
Pancreas5.55
PancreaticIslet7.45
ParietalLobe7.5
Pituitary8.1
Placenta8.95
Pons6.6
PrefrontalCortex8.35
Prostate8.05
Salivarygland5.6
SkeletalMuscle9.5
Skin5.95
SmoothMuscle7.7
Spinalcord7.25
SubthalamicNucleus6.3
SuperiorCervicalGanglion8.8
TemporalLobe6.35
Testis5.9
TestisGermCell5.7
TestisIntersitial6.1
TestisLeydigCell7.05
TestisSeminiferousTubule5.9
Thalamus7.05
Thymus5.45
Thyroid8.65
Tongue7.15
Tonsil6.75
Trachea5.75
TrigeminalGanglion8.1
Uterus5.65
UterusCorpus6.5
WholeBlood7.35
Wholebrain5.55
colon6.95
pineal_day8.4
pineal_night8.14
retina8.4
small_intestine6.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P53397
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.27 ± 0.44
Basal Forebrain5.95 ± 0.28
Basal Part of Pons5.12 ± 0.41
Cerebellar Cortex6.07 ± 0.26
Cerebellar Nuclei5.78 ± 0.4
Claustrum5.21 ± 0.56
Epithalamus5.94 ± 0.67
Frontal Lobe5.31 ± 0.52
Globus Pallidus6.19 ± 0.75
Hypothalamus5.45 ± 0.59
Insula5 ± 0.69
Limbic Lobe5.43 ± 0.61
Mesencephalon5.71 ± 0.46
Myelencephalon5.61 ± 0.59
Occipital Lobe6.1 ± 0.57
Parietal Lobe5.5 ± 0.49
Pontine Tegmentum5.53 ± 0.53
Striatum5.68 ± 0.73
Subthalamus5.01 ± 0.49
Temporal Lobe5.33 ± 0.43
Thalamus5.78 ± 0.46
White Matter7.04 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sp1CBCerebellum5.79
7.35
Sp1CTXCerebral cortex2.96
3.79
Sp1HIPHippocampal region1.91
1.96
Sp1HPFHippocampal formation1.95
1.77
Sp1HYHypothalamus1.5
2.17
Sp1LSXLateral septal complex0.76
0.85
Sp1MBMidbrain4.59
5.83
Sp1MYMedulla4.72
4.57
Sp1OLFOlfactory bulb4.73
4.59
Sp1PPons2.6
2.72
Sp1PALPallidum0.87
0.75
Sp1RHPRetrohippocampal region2.1
1.6
Sp1sAMYStriatum-like amygdalar nuclei0.14
0.18
Sp1STRStriatum1.04
1.17
Sp1STRdStriatum dorsal region0.61
0.7
Sp1STRvStriatum ventral region3.02
3.05
Sp1THThalamus7.88
11.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042682 31 40 70 SSSTGSSSSTGGGGQESQPSPLALLAATCSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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