Annotation Detail for SPG7
Basic Information Top
Gene Symbol: | SPG7 ( CAR,CMAR,FLJ37308,MGC126331,MGC126332,PGN,SPG5C ) |
---|---|
Gene Full Name: | spastic paraplegia 7 (pure and complicated autosomal recessive) |
Band: | 16q24.3 |
Quick Links | Entrez ID:6687; OMIM: 602783; Uniprot ID:SPG7_HUMAN; ENSEMBL ID: ENSG00000197912; HGNC ID: 11237 |
Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.185597
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
embryoid body | 10 / 70761 | 141 | |
blastocyst | 10 / 62319 | 160 | |
fetus | 34 / 564012 | 60 | |
neonate | 0 / 31097 | 0 | |
infant | 0 / 23620 | 0 | |
juvenile | 1 / 55556 | 17 | |
adult | 185 / 1939121 | 95 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 214494_s_at
Cell line | Expression level | Expression bar |
---|---|---|
721_B_lymphoblasts | 123.95 | |
Adipocyte | 64.5 | |
AdrenalCortex | 122.4 | |
Adrenalgland | 95.3 | |
Amygdala | 179.85 | |
Appendix | 64.25 | |
AtrioventricularNode | 32 | |
BDCA4+_DentriticCells | 174.6 | |
Bonemarrow | 56.85 | |
BronchialEpithelialCells | 51.05 | |
CD105+_Endothelial | 111.7 | |
CD14+_Monocytes | 160.5 | |
CD19+_BCells(neg._sel.) | 174.5 | |
CD33+_Myeloid | 243.65 | |
CD34+ | 318.05 | |
CD4+_Tcells | 551.7 | |
CD56+_NKCells | 202.7 | |
CD71+_EarlyErythroid | 61.65 | |
CD8+_Tcells | 605.35 | |
CardiacMyocytes | 74.4 | |
Caudatenucleus | 101.95 | |
Cerebellum | 90.95 | |
CerebellumPeduncles | 115.15 | |
CiliaryGanglion | 37 | |
CingulateCortex | 140.95 | |
Colorectaladenocarcinoma | 102.4 | |
DorsalRootGanglion | 45.9 | |
FetalThyroid | 331.95 | |
Fetalbrain | 161.7 | |
Fetalliver | 40.15 | |
Fetallung | 88.9 | |
GlobusPallidus | 86.65 | |
Heart | 147.1 | |
Hypothalamus | 210.95 | |
Kidney | 60.35 | |
Leukemia_chronicMyelogenousK-562 | 153.95 | |
Leukemia_promyelocytic-HL-60 | 47.9 | |
Leukemialymphoblastic(MOLT-4) | 107.1 | |
Liver | 196.5 | |
Lung | 148.6 | |
Lymphnode | 171.1 | |
Lymphoma_burkitts(Daudi) | 68.05 | |
Lymphoma_burkitts(Raji) | 116.25 | |
MedullaOblongata | 113.7 | |
OccipitalLobe | 123.25 | |
OlfactoryBulb | 55.6 | |
Ovary | 56.45 | |
Pancreas | 76.3 | |
PancreaticIslet | 93.25 | |
ParietalLobe | 104.05 | |
Pituitary | 90.4 | |
Placenta | 57.9 | |
Pons | 90 | |
PrefrontalCortex | 373.8 | |
Prostate | 201.05 | |
Salivarygland | 59.85 | |
SkeletalMuscle | 61.25 | |
Skin | 45.25 | |
SmoothMuscle | 61.55 | |
Spinalcord | 103.8 | |
SubthalamicNucleus | 110.9 | |
SuperiorCervicalGanglion | 33.45 | |
TemporalLobe | 76.65 | |
Testis | 102.55 | |
TestisGermCell | 152.65 | |
TestisIntersitial | 133.5 | |
TestisLeydigCell | 99 | |
TestisSeminiferousTubule | 133.8 | |
Thalamus | 130.9 | |
Thymus | 125.2 | |
Thyroid | 455.35 | |
Tongue | 102.95 | |
Tonsil | 100.3 | |
Trachea | 36.95 | |
TrigeminalGanglion | 58 | |
Uterus | 140.6 | |
UterusCorpus | 59.2 | |
WholeBlood | 56.35 | |
Wholebrain | 219.6 | |
colon | 88.15 | |
pineal_day | 321.9 | |
pineal_night | 226.76 | |
retina | 170.025 | |
small_intestine | 67.75 |
Human Whole Brain Microarrayview in Allen Brain Atlas
- Probe name: A_24_P5305
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue | Expression(mean ± stddev) | Expression Bar |
---|---|---|
Amygdala | 6.24 ± 0.48 | |
Basal Forebrain | 5.67 ± 0.1 | |
Basal Part of Pons | 5.96 ± 0.3 | |
Cerebellar Cortex | 5.9 ± 0.44 | |
Cerebellar Nuclei | 5.66 ± 0.46 | |
Claustrum | 6.27 ± 0.62 | |
Epithalamus | 5.21 ± 0.55 | |
Frontal Lobe | 5.77 ± 0.43 | |
Globus Pallidus | 5.86 ± 0.32 | |
Hypothalamus | 5.48 ± 0.41 | |
Insula | 5.74 ± 0.34 | |
Limbic Lobe | 6.02 ± 0.46 | |
Mesencephalon | 5.85 ± 0.43 | |
Myelencephalon | 5.84 ± 0.43 | |
Occipital Lobe | 5.92 ± 0.39 | |
Parietal Lobe | 5.84 ± 0.31 | |
Pontine Tegmentum | 5.65 ± 0.4 | |
Striatum | 5.6 ± 0.39 | |
Subthalamus | 5.73 ± 0.21 | |
Temporal Lobe | 5.82 ± 0.44 | |
Thalamus | 5.75 ± 0.35 | |
White Matter | 5.59 ± 0.25 |
Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
---|---|---|---|---|
Spg7 | CB | Cerebellum | 1.23 | |
1.67 | ||||
Spg7 | CTX | Cerebral cortex | 1.94 | |
2.67 | ||||
Spg7 | HIP | Hippocampal region | 1.09 | |
1.65 | ||||
Spg7 | HPF | Hippocampal formation | 1.45 | |
1.9 | ||||
Spg7 | HY | Hypothalamus | 0.28 | |
0.26 | ||||
Spg7 | LSX | Lateral septal complex | 0.28 | |
0.26 | ||||
Spg7 | MB | Midbrain | 0.8 | |
0.97 | ||||
Spg7 | MY | Medulla | 1.75 | |
2 | ||||
Spg7 | OLF | Olfactory bulb | 1.49 | |
1.76 | ||||
Spg7 | P | Pons | 1.16 | |
1.11 | ||||
Spg7 | PAL | Pallidum | 0.8 | |
1.64 | ||||
Spg7 | RHP | Retrohippocampal region | 2.04 | |
2.16 | ||||
Spg7 | sAMY | Striatum-like amygdalar nuclei | 1.38 | |
1.85 | ||||
Spg7 | STR | Striatum | 0.65 | |
0.9 | ||||
Spg7 | STRd | Striatum dorsal region | 0.69 | |
0.97 | ||||
Spg7 | STRv | Striatum ventral region | 0.28 | |
0.31 | ||||
Spg7 | TH | Thalamus | 0.47 | |
0.7 |
Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
---|---|---|---|---|---|
SPG7_HUMAN_226 | 15 | 226 | 240 | LRAAEDELNIEAKDR | PRIDE |