Annotation Detail for SPN
Basic Information Top
| Gene Symbol: | SPN ( CD43,GPL115,LSN ) |
|---|---|
| Gene Full Name: | sialophorin |
| Band: | 16p11.2 |
| Quick Links | Entrez ID:6693; OMIM: 182160; Uniprot ID:LEUK_HUMAN; ENSEMBL ID: ENSG00000197471; HGNC ID: 11249 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.632188
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 10 / 564012 | 17 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 19 / 1939121 | 9 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 9 / 95842 | 93 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 40 / 3360307 | 11 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 12 / 123478 | 97 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 4 / 48801 | 81 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 1 / 24145 | 41 | |
| liver | 3 / 207743 | 14 | |
| lung | 2 / 336974 | 5 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 8 / 53952 | 148 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 16 / 81131 | 197 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 206057_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 8 | |
| Adipocyte | 6.85 | |
| AdrenalCortex | 13.3 | |
| Adrenalgland | 5.4 | |
| Amygdala | 6.15 | |
| Appendix | 15.7 | |
| AtrioventricularNode | 32.1 | |
| BDCA4+_DentriticCells | 7.45 | |
| Bonemarrow | 8.5 | |
| BronchialEpithelialCells | 6.2 | |
| CD105+_Endothelial | 6.6 | |
| CD14+_Monocytes | 8.4 | |
| CD19+_BCells(neg._sel.) | 6.8 | |
| CD33+_Myeloid | 8.4 | |
| CD34+ | 8.35 | |
| CD4+_Tcells | 6.45 | |
| CD56+_NKCells | 45.65 | |
| CD71+_EarlyErythroid | 6.05 | |
| CD8+_Tcells | 5.9 | |
| CardiacMyocytes | 8.1 | |
| Caudatenucleus | 6.05 | |
| Cerebellum | 6.1 | |
| CerebellumPeduncles | 7.3 | |
| CiliaryGanglion | 25.9 | |
| CingulateCortex | 6.6 | |
| Colorectaladenocarcinoma | 5.95 | |
| DorsalRootGanglion | 31 | |
| FetalThyroid | 6.45 | |
| Fetalbrain | 6.45 | |
| Fetalliver | 6.15 | |
| Fetallung | 5.3 | |
| GlobusPallidus | 12.8 | |
| Heart | 7.75 | |
| Hypothalamus | 7.25 | |
| Kidney | 5.25 | |
| Leukemia_chronicMyelogenousK-562 | 6.1 | |
| Leukemia_promyelocytic-HL-60 | 5.65 | |
| Leukemialymphoblastic(MOLT-4) | 5.7 | |
| Liver | 8.2 | |
| Lung | 6.7 | |
| Lymphnode | 5.7 | |
| Lymphoma_burkitts(Daudi) | 8.1 | |
| Lymphoma_burkitts(Raji) | 8.7 | |
| MedullaOblongata | 6.05 | |
| OccipitalLobe | 6.05 | |
| OlfactoryBulb | 5.4 | |
| Ovary | 8.3 | |
| Pancreas | 5.05 | |
| PancreaticIslet | 6.6 | |
| ParietalLobe | 6.75 | |
| Pituitary | 8.3 | |
| Placenta | 6.3 | |
| Pons | 7.55 | |
| PrefrontalCortex | 5.5 | |
| Prostate | 6.9 | |
| Salivarygland | 20.35 | |
| SkeletalMuscle | 12 | |
| Skin | 24.1 | |
| SmoothMuscle | 8.4 | |
| Spinalcord | 6.9 | |
| SubthalamicNucleus | 8.9 | |
| SuperiorCervicalGanglion | 48.6 | |
| TemporalLobe | 7.25 | |
| Testis | 5.5 | |
| TestisGermCell | 5.45 | |
| TestisIntersitial | 7.2 | |
| TestisLeydigCell | 25.65 | |
| TestisSeminiferousTubule | 26.05 | |
| Thalamus | 6.5 | |
| Thymus | 5.5 | |
| Thyroid | 7.4 | |
| Tongue | 16.05 | |
| Tonsil | 7.45 | |
| Trachea | 5.5 | |
| TrigeminalGanglion | 26.75 | |
| Uterus | 5.1 | |
| UterusCorpus | 9.35 | |
| WholeBlood | 7.45 | |
| Wholebrain | 4.95 | |
| colon | 5.95 | |
| pineal_day | 6.1 | |
| pineal_night | 6.08 | |
| retina | 7.65 | |
| small_intestine | 4.85 | |
- Probe name: A_23_P433760
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.1 ± 0.68 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.11 ± 0.3 | |
| Basal Part of Pons | 5.72 ± 0.42 | |
| Cerebellar Cortex | 5.32 ± 0.52 | |
| Cerebellar Nuclei | 6.46 ± 0.6 | |
| Claustrum | 6.51 ± 0.79 | |
| Epithalamus | 4.81 ± 0.75 | |
| Frontal Lobe | 5.88 ± 0.71 | |
| Globus Pallidus | 6.52 ± 0.33 | |
| Hypothalamus | 5.62 ± 0.8 | |
| Insula | 5.64 ± 0.67 | |
| Limbic Lobe | 5.9 ± 0.74 | |
| Mesencephalon | 6.13 ± 0.52 | |
| Myelencephalon | 6.02 ± 0.79 | |
| Occipital Lobe | 5.96 ± 0.88 | |
| Parietal Lobe | 5.93 ± 0.58 | |
| Pontine Tegmentum | 5.91 ± 0.6 | |
| Striatum | 6.57 ± 0.67 | |
| Subthalamus | 6.23 ± 0.4 | |
| Temporal Lobe | 5.68 ± 0.68 | |
| Thalamus | 6.26 ± 0.51 | |
| White Matter | 5.87 ± 0.15 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Spn | CB | Cerebellum | 1.04 | |
| 1.6 | | |||
| Spn | CTX | Cerebral cortex | 2.22 | |
| 3.07 | | |||
| Spn | HIP | Hippocampal region | 0.79 | |
| 1.05 | | |||
| Spn | HPF | Hippocampal formation | 0.96 | |
| 1.67 | | |||
| Spn | HY | Hypothalamus | 0.66 | |
| 0.92 | | |||
| Spn | LSX | Lateral septal complex | 2.26 | |
| 1.56 | | |||
| Spn | MB | Midbrain | 0.85 | |
| 0.99 | | |||
| Spn | MY | Medulla | 2.93 | |
| 3.45 | | |||
| Spn | OLF | Olfactory bulb | 1.11 | |
| 1.13 | | |||
| Spn | P | Pons | 1.17 | |
| 1.1 | | |||
| Spn | PAL | Pallidum | 1.45 | |
| 1.57 | | |||
| Spn | RHP | Retrohippocampal region | 1.3 | |
| 2.73 | | |||
| Spn | sAMY | Striatum-like amygdalar nuclei | 0.56 | |
| 0.8 | | |||
| Spn | STR | Striatum | 0.97 | |
| 1.06 | | |||
| Spn | STRd | Striatum dorsal region | 0.91 | |
| 1.06 | | |||
| Spn | STRv | Striatum ventral region | 0.73 | |
| 0.9 | | |||
| Spn | TH | Thalamus | 1.02 | |
| 1.24 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| LEUK_HUMAN_0 | 0 | 0 | 0 | RPTLTTFFGR | PRIDE |
| PAp00006768 | 31 | 296 | 326 | RNGVVDAWAGPAQVPEEGAVTVTVGGSGGDK | Peptide Atlas |