AutismKB 2.0

Annotation Detail for SRP72


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Basic Information Top
Gene Symbol:SRP72 ( - )
Gene Full Name: signal recognition particle 72kDa
Band: 4q12
Quick LinksEntrez ID:6731; OMIM: 602122; Uniprot ID:SRP72_HUMAN; ENSEMBL ID: ENSG00000174780; HGNC ID: 11303
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst7 / 62319112
fetus80 / 564012141
neonate1 / 3109732
infant9 / 23620381
juvenile14 / 55556251
adult215 / 1939121110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma2 / 17475114
breast (mammary gland) tumor13 / 94178138
cervical tumor3 / 3436687
chondrosarcoma16 / 82823193
colorectal tumor20 / 114246175
esophageal tumor5 / 17290289
gastrointestinal tumor10 / 11936983
germ cell tumor30 / 263845113
glioma19 / 106883177
head and neck tumor10 / 13630273
kidney tumor1 / 6895914
leukemia30 / 95842313
liver tumor20 / 96359207
lung tumor7 / 10312767
lymphoma10 / 71755139
non-neoplasia11 / 97250113
normal350 / 3360307104
ovarian tumor6 / 7668278
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS27 / 125680214
prostate cancer20 / 102680194
retinoblastoma8 / 46356172
skin tumor15 / 124949120
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland5 / 33197150
ascites4 / 4001599
bladder1 / 2975733
blood23 / 123478186
bone9 / 71655125
bone marrow15 / 48801307
brain74 / 110098967
cervix7 / 48171145
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue39 / 215722180
esophagus5 / 20209247
eye24 / 211054113
heart12 / 89626133
intestine34 / 234472145
kidney15 / 21177770
larynx2 / 2414582
liver38 / 207743182
lung42 / 336974124
lymph8 / 44270180
lymph node17 / 91610185
mammary gland20 / 153271130
mouth3 / 6705244
muscle4 / 10771537
nerve1 / 1576863
ovary13 / 102051127
pancreas33 / 214812153
parathyroid5 / 20539243
pharynx10 / 41328241
pituitary gland1 / 1658560
placenta38 / 280825135
prostate27 / 189345142
salivary gland1 / 2015549
skin18 / 21057485
spleen5 / 5395292
stomach6 / 9661962
testis36 / 330442108
thymus9 / 81131110
thyroid3 / 4747363
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord1 / 1368073
uterus33 / 232878141
vascular14 / 51780270
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208800_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.5
Adipocyte13.7
AdrenalCortex4.5
Adrenalgland3.6
Amygdala6.7
Appendix4.35
AtrioventricularNode3.3
BDCA4+_DentriticCells106.55
Bonemarrow4.25
BronchialEpithelialCells129.65
CD105+_Endothelial30.65
CD14+_Monocytes24.6
CD19+_BCells(neg._sel.)55.6
CD33+_Myeloid27.6
CD34+51.9
CD4+_Tcells8.6
CD56+_NKCells52.5
CD71+_EarlyErythroid12.6
CD8+_Tcells17.05
CardiacMyocytes6.1
Caudatenucleus3.9
Cerebellum3.45
CerebellumPeduncles4.8
CiliaryGanglion3.05
CingulateCortex4.4
Colorectaladenocarcinoma5.8
DorsalRootGanglion3.3
FetalThyroid4.2
Fetalbrain5.2
Fetalliver11.7
Fetallung7.9
GlobusPallidus3.15
Heart5.4
Hypothalamus7.15
Kidney3.5
Leukemia_chronicMyelogenousK-56248.6
Leukemia_promyelocytic-HL-6029.7
Leukemialymphoblastic(MOLT-4)37.95
Liver5.65
Lung4.7
Lymphnode8.5
Lymphoma_burkitts(Daudi)18.5
Lymphoma_burkitts(Raji)7.45
MedullaOblongata3.95
OccipitalLobe6.7
OlfactoryBulb3.45
Ovary2.9
Pancreas3.65
PancreaticIslet6.8
ParietalLobe4.5
Pituitary6.2
Placenta4.5
Pons4.1
PrefrontalCortex5.5
Prostate5.05
Salivarygland8.75
SkeletalMuscle4.95
Skin3.3
SmoothMuscle24.8
Spinalcord4.65
SubthalamicNucleus3.9
SuperiorCervicalGanglion5.1
TemporalLobe3.95
Testis3.65
TestisGermCell3.55
TestisIntersitial3.85
TestisLeydigCell4.25
TestisSeminiferousTubule3.7
Thalamus4.4
Thymus3.55
Thyroid11.9
Tongue4.2
Tonsil5.8
Trachea3.65
TrigeminalGanglion4.35
Uterus10.25
UterusCorpus3.95
WholeBlood19.65
Wholebrain3.75
colon4.65
pineal_day9.76
pineal_night13
retina5.25
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P174713
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.95 ± 0.23
Basal Forebrain7.98 ± 0.19
Basal Part of Pons7.97 ± 0.22
Cerebellar Cortex7.96 ± 0.28
Cerebellar Nuclei7.95 ± 0.42
Claustrum8.02 ± 0.28
Epithalamus8.23 ± 0.35
Frontal Lobe8.04 ± 0.29
Globus Pallidus8.13 ± 0.18
Hypothalamus8.33 ± 0.32
Insula8.13 ± 0.2
Limbic Lobe7.96 ± 0.26
Mesencephalon8.05 ± 0.26
Myelencephalon7.98 ± 0.27
Occipital Lobe7.95 ± 0.29
Parietal Lobe7.96 ± 0.24
Pontine Tegmentum8 ± 0.29
Striatum7.91 ± 0.21
Subthalamus8 ± 0.27
Temporal Lobe7.98 ± 0.26
Thalamus7.95 ± 0.24
White Matter8.48 ± 0.07
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003934 15 37 51 ILQINKDDVTALHCK Peptide Atlas
SRP72_HUMAN_600 17 600 616 GTQGATAGASSELDASK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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