AutismKB 2.0

Annotation Detail for SSBP1


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Basic Information Top
Gene Symbol:SSBP1 ( Mt-SSB,SOSS-B1,SSBP,mtSSB )
Gene Full Name: single-stranded DNA binding protein 1
Band: 7q34
Quick LinksEntrez ID:6742; OMIM: 600439; Uniprot ID:SSBP_HUMAN; ENSEMBL ID: ENSG00000106028; HGNC ID: 11317
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst4 / 6231964
fetus57 / 564012101
neonate4 / 31097128
infant0 / 236200 
juvenile0 / 555560 
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor3 / 17290173
gastrointestinal tumor7 / 11936958
germ cell tumor11 / 26384541
glioma14 / 106883130
head and neck tumor5 / 13630236
kidney tumor9 / 68959130
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal250 / 336030774
ovarian tumor21 / 76682273
pancreatic tumor126 / 1046161204
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer8 / 10268077
retinoblastoma2 / 4635643
skin tumor82 / 124949656
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder3 / 29757100
blood10 / 12347880
bone5 / 7165569
bone marrow5 / 48801102
brain60 / 110098954
cervix1 / 4817120
connective tissue4 / 14925526
ear4 / 16212246
embryonic tissue17 / 21572278
esophagus3 / 20209148
eye7 / 21105433
heart17 / 89626189
intestine10 / 23447242
kidney23 / 211777108
larynx0 / 241450 
liver23 / 207743110
lung24 / 33697471
lymph0 / 442700 
lymph node14 / 91610152
mammary gland8 / 15327152
mouth5 / 6705274
muscle3 / 10771527
nerve0 / 157680 
ovary21 / 102051205
pancreas142 / 214812661
parathyroid13 / 20539632
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta5 / 28082517
prostate17 / 18934589
salivary gland5 / 20155248
skin90 / 210574427
spleen0 / 539520 
stomach7 / 9661972
testis17 / 33044251
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord4 / 13680292
uterus20 / 23287885
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202591_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts2017.5
Adipocyte211.95
AdrenalCortex89.2
Adrenalgland64.9
Amygdala219.8
Appendix19.65
AtrioventricularNode14.4
BDCA4+_DentriticCells581
Bonemarrow83.05
BronchialEpithelialCells1101.8
CD105+_Endothelial943.95
CD14+_Monocytes503.7
CD19+_BCells(neg._sel.)728.05
CD33+_Myeloid640.25
CD34+1070.6
CD4+_Tcells665.1
CD56+_NKCells688.9
CD71+_EarlyErythroid376.05
CD8+_Tcells583.05
CardiacMyocytes537.3
Caudatenucleus81
Cerebellum37.45
CerebellumPeduncles23.35
CiliaryGanglion37.15
CingulateCortex67.5
Colorectaladenocarcinoma503.2
DorsalRootGanglion30.25
FetalThyroid40.35
Fetalbrain64.1
Fetalliver198.6
Fetallung186.1
GlobusPallidus29.9
Heart23.35
Hypothalamus186.65
Kidney46
Leukemia_chronicMyelogenousK-562887.45
Leukemia_promyelocytic-HL-60696.05
Leukemialymphoblastic(MOLT-4)992.95
Liver45.4
Lung79.6
Lymphnode152.4
Lymphoma_burkitts(Daudi)1098.55
Lymphoma_burkitts(Raji)311.95
MedullaOblongata43.25
OccipitalLobe74.9
OlfactoryBulb72.65
Ovary81.15
Pancreas147.85
PancreaticIslet312.75
ParietalLobe44.4
Pituitary119.25
Placenta172.1
Pons27.8
PrefrontalCortex123.05
Prostate100.9
Salivarygland113
SkeletalMuscle24.1
Skin32.9
SmoothMuscle917.3
Spinalcord61.05
SubthalamicNucleus50.1
SuperiorCervicalGanglion20.7
TemporalLobe44.1
Testis322.65
TestisGermCell287.85
TestisIntersitial257.85
TestisLeydigCell164.45
TestisSeminiferousTubule189.65
Thalamus126.1
Thymus286.35
Thyroid288.7
Tongue111.65
Tonsil254.45
Trachea73.3
TrigeminalGanglion18.05
Uterus132.75
UterusCorpus31.6
WholeBlood268.3
Wholebrain185.45
colon415.45
pineal_day336.8
pineal_night311.04
retina150.825
small_intestine327.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15014_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.72 ± 0.19
Basal Forebrain10.55 ± 0.16
Basal Part of Pons10.58 ± 0.18
Cerebellar Cortex10.45 ± 0.16
Cerebellar Nuclei10.63 ± 0.18
Claustrum10.75 ± 0.17
Epithalamus10.56 ± 0.07
Frontal Lobe10.65 ± 0.21
Globus Pallidus10.65 ± 0.2
Hypothalamus10.74 ± 0.17
Insula10.61 ± 0.25
Limbic Lobe10.61 ± 0.27
Mesencephalon10.6 ± 0.22
Myelencephalon10.56 ± 0.22
Occipital Lobe10.37 ± 0.18
Parietal Lobe10.58 ± 0.19
Pontine Tegmentum10.63 ± 0.2
Striatum10.67 ± 0.16
Subthalamus10.69 ± 0.15
Temporal Lobe10.63 ± 0.22
Thalamus10.51 ± 0.15
White Matter10.9 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ssbp1CBCerebellum5.16
6.35
Ssbp1CTXCerebral cortex4.06
3.64
Ssbp1HIPHippocampal region8.35
10.62
Ssbp1HPFHippocampal formation7.84
8.78
Ssbp1HYHypothalamus2
1.78
Ssbp1LSXLateral septal complex1.11
0.96
Ssbp1MBMidbrain2.45
3.42
Ssbp1MYMedulla2.07
3.41
Ssbp1OLFOlfactory bulb2.47
3.33
Ssbp1PPons2.99
4.27
Ssbp1PALPallidum0.59
0.56
Ssbp1RHPRetrohippocampal region7.03
6.26
Ssbp1sAMYStriatum-like amygdalar nuclei0.15
0.15
Ssbp1STRStriatum0.77
0.8
Ssbp1STRdStriatum dorsal region0.98
1.05
Ssbp1STRvStriatum ventral region0.16
0.12
Ssbp1THThalamus3.39
3.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042128 18 128 145 QATTIIADNIIFLSDQTK Peptide Atlas
SSBP_HUMAN_0 0 0 0 IDYGEYMDKNNVR PRIDE
SSBP_HUMAN_0 0 0 0 NPVTIFSLATNEMWR PRIDE
SSBP_HUMAN_0 0 0 0 SGDSEVYQLGDVSQK PRIDE
SSBP_HUMAN_113 13 113 125 IDYGEYMDKNNVR PRIDE
SSBP_HUMAN_126 19 126 144 RQATTIIADNIIFLSDQTK PRIDE
SSBP_HUMAN_127 18 127 144 QATTIIADNIIFLSDQTK PRIDE
SSBP_HUMAN_127 21 127 147 QATTIIADNIIFLSDQTKEKE PRIDE
SSBP_HUMAN_128 21 128 148 QATTIIADNIIFLSDQTKEKE PRIDE
SSBP_HUMAN_17 12 17 28 ESETTTSLVLER PRIDE
SSBP_HUMAN_38 8 38 45 VGQDPVLR PRIDE
SSBP_HUMAN_46 20 46 65 QVEGKNPVTIFSLATNEMWR PRIDE
SSBP_HUMAN_51 15 51 65 NPVTIFSLATNEMWR PRIDE
SSBP_HUMAN_66 15 66 80 SGDSEVYQLGDVSQK PRIDE
SSBP_HUMAN_67 15 67 81 SGDSEVYQLGDVSQK PRIDE
SSBP_HUMAN_86 9 86 94 ISVFRPGLR PRIDE
SSBP_HUMAN_95 8 95 102 DVAYQYVK PRIDE
SSBP_HUMAN_95 9 95 103 DVAYQYVKK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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