AutismKB 2.0

Annotation Detail for SSR1


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Basic Information Top
Gene Symbol:SSR1 ( DKFZp781N23103,FLJ14232,FLJ22100,FLJ23034,FLJ78242,FLJ93042,TRAPA )
Gene Full Name: signal sequence receptor, alpha
Band: 6p24.3
Quick LinksEntrez ID:6745; OMIM: 600868; Uniprot ID:SSRA_HUMAN; ENSEMBL ID: ENSG00000124783; HGNC ID: 11323
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst5 / 6231980
fetus87 / 564012154
neonate13 / 31097418
infant1 / 2362042
juvenile39 / 55556701
adult333 / 1939121171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma3 / 17475171
breast (mammary gland) tumor22 / 94178233
cervical tumor1 / 3436629
chondrosarcoma16 / 82823193
colorectal tumor20 / 114246175
esophageal tumor4 / 17290231
gastrointestinal tumor17 / 119369142
germ cell tumor77 / 263845291
glioma13 / 106883121
head and neck tumor26 / 136302190
kidney tumor5 / 6895972
leukemia13 / 95842135
liver tumor45 / 96359467
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia32 / 97250329
normal563 / 3360307167
ovarian tumor11 / 76682143
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer21 / 102680204
retinoblastoma8 / 46356172
skin tumor13 / 124949104
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites5 / 40015124
bladder3 / 29757100
blood24 / 123478194
bone9 / 71655125
bone marrow8 / 48801163
brain137 / 1100989124
cervix2 / 4817141
connective tissue46 / 149255308
ear2 / 16212123
embryonic tissue22 / 215722101
esophagus4 / 20209197
eye38 / 211054180
heart8 / 8962689
intestine40 / 234472170
kidney28 / 211777132
larynx0 / 241450 
liver68 / 207743327
lung42 / 336974124
lymph0 / 442700 
lymph node19 / 91610207
mammary gland31 / 153271202
mouth22 / 67052328
muscle30 / 107715278
nerve1 / 1576863
ovary15 / 102051146
pancreas23 / 214812107
parathyroid0 / 205390 
pharynx15 / 41328362
pituitary gland0 / 165850 
placenta51 / 280825181
prostate36 / 189345190
salivary gland4 / 20155198
skin47 / 210574223
spleen14 / 53952259
stomach13 / 96619134
testis77 / 330442233
thymus21 / 81131258
thyroid7 / 47473147
tonsil1 / 1699958
trachea15 / 52413286
umbilical cord3 / 13680219
uterus31 / 232878133
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200890_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts147.15
Adipocyte153.95
AdrenalCortex51.75
Adrenalgland64
Amygdala31.35
Appendix58.55
AtrioventricularNode53.05
BDCA4+_DentriticCells456.9
Bonemarrow95.65
BronchialEpithelialCells177.15
CD105+_Endothelial42.55
CD14+_Monocytes122.15
CD19+_BCells(neg._sel.)44.55
CD33+_Myeloid247.1
CD34+229.9
CD4+_Tcells70
CD56+_NKCells104.35
CD71+_EarlyErythroid30.55
CD8+_Tcells61.2
CardiacMyocytes107
Caudatenucleus33.05
Cerebellum31.4
CerebellumPeduncles46.2
CiliaryGanglion60.85
CingulateCortex38.25
Colorectaladenocarcinoma35.5
DorsalRootGanglion36.85
FetalThyroid43.95
Fetalbrain35.55
Fetalliver149.55
Fetallung41.8
GlobusPallidus29.3
Heart54.9
Hypothalamus37.35
Kidney37.55
Leukemia_chronicMyelogenousK-56249.85
Leukemia_promyelocytic-HL-6059.45
Leukemialymphoblastic(MOLT-4)48.1
Liver58
Lung35.4
Lymphnode40.85
Lymphoma_burkitts(Daudi)71.65
Lymphoma_burkitts(Raji)48
MedullaOblongata58.05
OccipitalLobe33.5
OlfactoryBulb41.3
Ovary31.25
Pancreas81.1
PancreaticIslet122.6
ParietalLobe46.6
Pituitary104.95
Placenta100.2
Pons50.45
PrefrontalCortex42.65
Prostate65.05
Salivarygland64.45
SkeletalMuscle64.45
Skin47.35
SmoothMuscle161.25
Spinalcord41.5
SubthalamicNucleus36.65
SuperiorCervicalGanglion67.15
TemporalLobe53.05
Testis35.6
TestisGermCell27.95
TestisIntersitial37.3
TestisLeydigCell37.95
TestisSeminiferousTubule31.55
Thalamus36.95
Thymus41.9
Thyroid71.75
Tongue45.6
Tonsil87.8
Trachea114.95
TrigeminalGanglion63.05
Uterus63.05
UterusCorpus39.95
WholeBlood118.35
Wholebrain21
colon163.3
pineal_day60.2
pineal_night51.88
retina63.35
small_intestine469.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P544882
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.38 ± 0.41
Basal Forebrain7.65 ± 0.26
Basal Part of Pons7.73 ± 0.11
Cerebellar Cortex7.84 ± 0.21
Cerebellar Nuclei7.89 ± 0.19
Claustrum7.41 ± 0.48
Epithalamus7.58 ± 0.26
Frontal Lobe7.58 ± 0.32
Globus Pallidus7.7 ± 0.34
Hypothalamus7.94 ± 0.23
Insula7.52 ± 0.38
Limbic Lobe7.44 ± 0.32
Mesencephalon7.62 ± 0.38
Myelencephalon7.51 ± 0.35
Occipital Lobe7.59 ± 0.24
Parietal Lobe7.58 ± 0.31
Pontine Tegmentum7.61 ± 0.31
Striatum7.69 ± 0.37
Subthalamus7.94 ± 0.32
Temporal Lobe7.49 ± 0.3
Thalamus7.55 ± 0.23
White Matter8.29 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ssr1CBCerebellum50.51
51.55
Ssr1CTXCerebral cortex76.49
49.92
Ssr1HIPHippocampal region72.14
59.18
Ssr1HPFHippocampal formation79.15
59.13
Ssr1HYHypothalamus100
69.64
Ssr1LSXLateral septal complex63.66
35.27
Ssr1MBMidbrain72.33
48.87
Ssr1MYMedulla81.24
64.59
Ssr1OLFOlfactory bulb81.82
52.38
Ssr1PPons78.16
60.82
Ssr1PALPallidum61.45
40.84
Ssr1RHPRetrohippocampal region80.43
57.27
Ssr1sAMYStriatum-like amygdalar nuclei73.55
47.89
Ssr1STRStriatum45.55
24.45
Ssr1STRdStriatum dorsal region36.3
19.47
Ssr1STRvStriatum ventral region51.75
24.09
Ssr1THThalamus47.87
28.72
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00034089 11 92 102 GEDFPANNIVK Peptide Atlas
SSRA_HUMAN_111 15 111 125 GTEDFIVESLDASFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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