AutismKB 2.0

Annotation Detail for SST


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Basic Information Top
Gene Symbol:SST ( SMST )
Gene Full Name: somatostatin
Band: 3q27.3
Quick LinksEntrez ID:6750; OMIM: 182450; Uniprot ID:SMS_HUMAN; ENSEMBL ID: ENSG00000157005; HGNC ID: 11329
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult16 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal448 / 3360307133
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas417 / 2148121941
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach3 / 9661931
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213921_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.75
Adipocyte8
AdrenalCortex11.2
Adrenalgland9.25
Amygdala560.7
Appendix9
AtrioventricularNode12.75
BDCA4+_DentriticCells5.95
Bonemarrow8.5
BronchialEpithelialCells7.45
CD105+_Endothelial7.55
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)8.05
CD33+_Myeloid8.9
CD34+7.8
CD4+_Tcells7.7
CD56+_NKCells8.05
CD71+_EarlyErythroid7.45
CD8+_Tcells6.75
CardiacMyocytes12.1
Caudatenucleus100.25
Cerebellum7.45
CerebellumPeduncles9.6
CiliaryGanglion30.45
CingulateCortex53.95
Colorectaladenocarcinoma7.35
DorsalRootGanglion34.1
FetalThyroid7.7
Fetalbrain126.9
Fetalliver9.15
Fetallung6.35
GlobusPallidus35.95
Heart12.25
Hypothalamus522.5
Kidney7.05
Leukemia_chronicMyelogenousK-5627.1
Leukemia_promyelocytic-HL-607.15
Leukemialymphoblastic(MOLT-4)7.25
Liver10.9
Lung8.55
Lymphnode6.75
Lymphoma_burkitts(Daudi)10.4
Lymphoma_burkitts(Raji)14.25
MedullaOblongata25.5
OccipitalLobe133.5
OlfactoryBulb6.75
Ovary5.7
Pancreas156.2
PancreaticIslet6858.55
ParietalLobe82
Pituitary17.25
Placenta7.8
Pons53.95
PrefrontalCortex10
Prostate9.7
Salivarygland6.55
SkeletalMuscle10.8
Skin7.5
SmoothMuscle8.75
Spinalcord43.3
SubthalamicNucleus23
SuperiorCervicalGanglion11.15
TemporalLobe56.4
Testis6.75
TestisGermCell6.5
TestisIntersitial6.9
TestisLeydigCell8.35
TestisSeminiferousTubule6.75
Thalamus34.75
Thymus6.1
Thyroid9.75
Tongue8.6
Tonsil8.7
Trachea6.7
TrigeminalGanglion13.8
Uterus6.25
UterusCorpus7.75
WholeBlood8.4
Wholebrain587.25
colon12.85
pineal_day400.84
pineal_night588.32
retina8.8
small_intestine76.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14458_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.95 ± 0.42
Basal Forebrain8.83 ± 0.22
Basal Part of Pons8.24 ± 0.28
Cerebellar Cortex7.84 ± 0.46
Cerebellar Nuclei8.6 ± 1.16
Claustrum8.75 ± 0.41
Epithalamus10.08 ± 1.05
Frontal Lobe9.07 ± 0.7
Globus Pallidus9.9 ± 0.92
Hypothalamus9.84 ± 1.13
Insula9.32 ± 0.45
Limbic Lobe8.6 ± 0.82
Mesencephalon8.84 ± 0.89
Myelencephalon9.02 ± 0.87
Occipital Lobe7.43 ± 0.93
Parietal Lobe8.57 ± 0.57
Pontine Tegmentum8.55 ± 0.88
Striatum8.67 ± 0.89
Subthalamus8.58 ± 0.67
Temporal Lobe8.82 ± 0.68
Thalamus8.45 ± 0.88
White Matter7.35 ± 0.87
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SstCBCerebellum9.17
12.74
SstCTXCerebral cortex26.27
49.71
SstHIPHippocampal region46.68
68.39
SstHPFHippocampal formation44.78
69.4
SstHYHypothalamus27.72
47.91
SstLSXLateral septal complex69.93
100
SstMBMidbrain30.18
39.84
SstMYMedulla41.1
55.94
SstOLFOlfactory bulb21.55
34.4
SstPPons28.92
40.32
SstPALPallidum26.79
43.71
SstRHPRetrohippocampal region42.37
71.57
SstsAMYStriatum-like amygdalar nuclei40.7
67.01
SstSTRStriatum22.02
36.2
SstSTRdStriatum dorsal region8.41
18.33
SstSTRvStriatum ventral region37.36
44.6
SstTHThalamus23.77
35.43
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00136447 13 38 50 SLAAAAGKQELAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018