AutismKB 2.0

Annotation Detail for ST14


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Basic Information Top
Gene Symbol:ST14 ( HAI,MT-SP1,MTSP1,PRSS14,SNC19,TADG15,TMPRSS14 )
Gene Full Name: suppression of tumorigenicity 14 (colon carcinoma)
Band: 11q24.3
Quick LinksEntrez ID:6768; OMIM: 606797; Uniprot ID:ST14_HUMAN; ENSEMBL ID: ENSG00000149418; HGNC ID: 11344
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult158 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor70 / 114246612
esophageal tumor1 / 1729057
gastrointestinal tumor42 / 119369351
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor17 / 136302124
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor11 / 103127106
lymphoma13 / 71755181
non-neoplasia7 / 9725071
normal104 / 336030730
ovarian tumor12 / 76682156
pancreatic tumor24 / 104616229
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites7 / 40015174
bladder6 / 29757201
blood5 / 12347840
bone2 / 7165527
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus2 / 2020998
eye2 / 2110549
heart9 / 89626100
intestine87 / 234472371
kidney10 / 21177747
larynx1 / 2414541
liver4 / 20774319
lung35 / 336974103
lymph7 / 44270158
lymph node11 / 91610120
mammary gland12 / 15327178
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary14 / 102051137
pancreas34 / 214812158
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta13 / 28082546
prostate15 / 18934579
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach30 / 96619310
testis2 / 3304426
thymus2 / 8113124
thyroid12 / 47473252
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202005_at
Cell line Expression level Expression bar
721_B_lymphoblasts65.5
Adipocyte77.2
AdrenalCortex113.75
Adrenalgland64.1
Amygdala60.8
Appendix65.25
AtrioventricularNode57.45
BDCA4+_DentriticCells471.35
Bonemarrow73.9
BronchialEpithelialCells280.45
CD105+_Endothelial61.55
CD14+_Monocytes139.6
CD19+_BCells(neg._sel.)84.6
CD33+_Myeloid102.3
CD34+72.5
CD4+_Tcells68.8
CD56+_NKCells61.45
CD71+_EarlyErythroid70.6
CD8+_Tcells56.05
CardiacMyocytes353.05
Caudatenucleus69.8
Cerebellum62.05
CerebellumPeduncles101
CiliaryGanglion55.5
CingulateCortex97.35
Colorectaladenocarcinoma211.25
DorsalRootGanglion68.05
FetalThyroid197.65
Fetalbrain63.6
Fetalliver65.65
Fetallung68.65
GlobusPallidus74.2
Heart90.55
Hypothalamus59.85
Kidney91.45
Leukemia_chronicMyelogenousK-56271.4
Leukemia_promyelocytic-HL-6096.35
Leukemialymphoblastic(MOLT-4)52.45
Liver174.15
Lung257.7
Lymphnode64.1
Lymphoma_burkitts(Daudi)248.5
Lymphoma_burkitts(Raji)106.6
MedullaOblongata66.5
OccipitalLobe97.8
OlfactoryBulb51.3
Ovary47.7
Pancreas308.6
PancreaticIslet85.6
ParietalLobe82.05
Pituitary111.9
Placenta96.15
Pons115.9
PrefrontalCortex96.55
Prostate364.75
Salivarygland96.3
SkeletalMuscle91.5
Skin60.7
SmoothMuscle71.55
Spinalcord92.55
SubthalamicNucleus69.75
SuperiorCervicalGanglion78.8
TemporalLobe78.1
Testis65.7
TestisGermCell56.3
TestisIntersitial64.15
TestisLeydigCell71.45
TestisSeminiferousTubule65
Thalamus131.5
Thymus77.15
Thyroid320.8
Tongue97.55
Tonsil89.25
Trachea133.25
TrigeminalGanglion84.8
Uterus41.95
UterusCorpus43.35
WholeBlood45.85
Wholebrain37.75
colon361
pineal_day69.98
pineal_night71.44
retina91.025
small_intestine356.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14329_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.54 ± 0.94
Basal Forebrain2.05 ± 0.42
Basal Part of Pons2.15 ± 0.59
Cerebellar Cortex2.32 ± 0.63
Cerebellar Nuclei2.31 ± 0.63
Claustrum2.69 ± 0.8
Epithalamus1.87 ± 0.91
Frontal Lobe2.24 ± 0.7
Globus Pallidus2.1 ± 0.53
Hypothalamus2.06 ± 0.58
Insula2.2 ± 0.65
Limbic Lobe2.2 ± 0.64
Mesencephalon2.28 ± 0.66
Myelencephalon2.25 ± 0.58
Occipital Lobe2.25 ± 0.71
Parietal Lobe2.24 ± 0.71
Pontine Tegmentum2.18 ± 0.72
Striatum2 ± 0.78
Subthalamus2.36 ± 0.53
Temporal Lobe2.2 ± 0.62
Thalamus2.16 ± 0.66
White Matter1.47 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
St14CBCerebellum15.01
16.53
St14CTXCerebral cortex25.95
18.1
St14HIPHippocampal region19.87
18.99
St14HPFHippocampal formation18.99
16.91
St14HYHypothalamus0.84
0.72
St14LSXLateral septal complex2.79
1.6
St14MBMidbrain3.84
3.45
St14MYMedulla6.68
7.25
St14OLFOlfactory bulb22.11
16.77
St14PPons3.89
4.08
St14PALPallidum2.16
1.71
St14RHPRetrohippocampal region17.76
14.22
St14sAMYStriatum-like amygdalar nuclei16.79
11.29
St14STRStriatum7.05
4.52
St14STRdStriatum dorsal region6.37
4.02
St14STRvStriatum ventral region6.03
3.74
St14THThalamus14.04
11.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002432 32 429 460 FHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018