AutismKB 2.0

Annotation Detail for STAT1


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Basic Information Top
Gene Symbol:STAT1 ( DKFZp686B04100,ISGF-3,STAT91 )
Gene Full Name: signal transducer and activator of transcription 1, 91kDa
Band: 2q32.2
Quick LinksEntrez ID:6772; OMIM: 600555; Uniprot ID:STAT1_HUMAN; ENSEMBL ID: ENSG00000115415; HGNC ID: 11362
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor43 / 119369360
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal44 / 336030713
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach43 / 96619445
testis6 / 33044218
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus11 / 23287847
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: AFFX-HUMISGF3A/M97935_MA_at
Cell line Expression level Expression bar
721_B_lymphoblasts65.9
Adipocyte6.45
AdrenalCortex5.3
Adrenalgland4.75
Amygdala5.05
Appendix5.2
AtrioventricularNode4.45
BDCA4+_DentriticCells53.35
Bonemarrow5.2
BronchialEpithelialCells5.1
CD105+_Endothelial5.15
CD14+_Monocytes11.15
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid18.4
CD34+6.75
CD4+_Tcells62
CD56+_NKCells20.55
CD71+_EarlyErythroid5
CD8+_Tcells47.95
CardiacMyocytes42.55
Caudatenucleus4.9
Cerebellum4.65
CerebellumPeduncles5.5
CiliaryGanglion4.4
CingulateCortex5.2
Colorectaladenocarcinoma5.1
DorsalRootGanglion4.5
FetalThyroid5.05
Fetalbrain5.05
Fetalliver4.75
Fetallung4.7
GlobusPallidus4.4
Heart5.45
Hypothalamus5.35
Kidney4.6
Leukemia_chronicMyelogenousK-5624.95
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)4.6
Liver5.8
Lung5.4
Lymphnode6.8
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)5.75
MedullaOblongata4.9
OccipitalLobe4.9
OlfactoryBulb4.55
Ovary4.15
Pancreas4.55
PancreaticIslet5.45
ParietalLobe5.3
Pituitary5.7
Placenta5.25
Pons5
PrefrontalCortex5.45
Prostate5.55
Salivarygland5.05
SkeletalMuscle5.55
Skin4.55
SmoothMuscle27.95
Spinalcord5.25
SubthalamicNucleus4.95
SuperiorCervicalGanglion5.65
TemporalLobe4.9
Testis4.8
TestisGermCell4.7
TestisIntersitial4.7
TestisLeydigCell5.1
TestisSeminiferousTubule4.65
Thalamus5.2
Thymus4.7
Thyroid5.6
Tongue5.1
Tonsil11.05
Trachea5.4
TrigeminalGanglion5.15
Uterus4.6
UterusCorpus4.95
WholeBlood5.95
Wholebrain4.75
colon5.5
pineal_day5.68
pineal_night5.6
retina5.525
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16759_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.21 ± 0.28
Basal Forebrain6.24 ± 0.13
Basal Part of Pons6.23 ± 0.26
Cerebellar Cortex6.19 ± 0.23
Cerebellar Nuclei6.62 ± 0.23
Claustrum6.43 ± 0.48
Epithalamus6.36 ± 0.14
Frontal Lobe6.23 ± 0.31
Globus Pallidus6.64 ± 0.28
Hypothalamus6.45 ± 0.32
Insula6.21 ± 0.24
Limbic Lobe6.35 ± 0.27
Mesencephalon6.32 ± 0.32
Myelencephalon6.38 ± 0.32
Occipital Lobe6.51 ± 0.26
Parietal Lobe6.25 ± 0.27
Pontine Tegmentum6.29 ± 0.33
Striatum6.41 ± 0.48
Subthalamus6.42 ± 0.24
Temporal Lobe6.25 ± 0.27
Thalamus6.24 ± 0.29
White Matter6.72 ± 0.06
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007249 14 162 175 SLEDLQDEYDFKCK Peptide Atlas
STAT1_HUMAN_13 18 13 30 FLEQVHQLYDDSFPMEIR PRIDE
STAT1_HUMAN_14 18 14 31 FLEQVHQLYDDSFPMEIR PRIDE
STAT1_HUMAN_161 12 161 172 SLEDLQDEYDFK PRIDE
STAT1_HUMAN_304 17 304 320 TFSLFQQLIQSSFVVER PRIDE
STAT1_HUMAN_31 25 31 55 QYLAQWLEKQDWEHAANDVSFATIR PRIDE
STAT1_HUMAN_350 9 350 358 LQELNYNLK PRIDE
STAT1_HUMAN_389 17 389 405 VMNMEESTNGSLAAEFR PRIDE
STAT1_HUMAN_482 12 482 493 NLSFFLTPPCAR PRIDE
STAT1_HUMAN_512 13 512 524 GLNVDQLNMLGEK PRIDE
STAT1_HUMAN_525 16 525 540 LLGPNASPDGLIPWTR PRIDE
STAT1_HUMAN_56 14 56 69 FHDLLSQLDDQYSR PRIDE
STAT1_HUMAN_637 12 637 648 ELSAVTFPDIIR PRIDE
STAT1_HUMAN_652 13 652 664 VMAAENIPENPLK PRIDE
STAT1_HUMAN_665 14 665 678 YLYPNIDKDHAFGK PRIDE
STAT1_HUMAN_685 12 685 696 EAPEPMELDGPK PRIDE
STAT1_HUMAN_686 12 686 697 EAPEPMELDGPK PRIDE
STAT1_HUMAN_70 14 70 83 FSLENNFLLQHNIR PRIDE
STAT1_HUMAN_703 13 703 715 TELISVSEVHPSR PRIDE
STAT1_HUMAN_717 20 717 736 LQTTDNLLPMSPEEFDEVSR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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