AutismKB 2.0

Annotation Detail for STAT4


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Basic Information Top
Gene Symbol:STAT4 ( SLEB11 )
Gene Full Name: signal transducer and activator of transcription 4
Band: 2q32.2-q32.3
Quick LinksEntrez ID:6775; OMIM: 600558; Uniprot ID:STAT4_HUMAN; ENSEMBL ID: ENSG00000138378; HGNC ID: 11365
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal66 / 336030719
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone0 / 716550 
bone marrow1 / 4880120
brain21 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine2 / 2344728
kidney1 / 2117774
larynx2 / 2414582
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen5 / 5395292
stomach0 / 966190 
testis16 / 33044248
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206118_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.45
Adipocyte4.8
AdrenalCortex5.2
Adrenalgland4.25
Amygdala5.25
Appendix5.55
AtrioventricularNode3.9
BDCA4+_DentriticCells6.45
Bonemarrow4.9
BronchialEpithelialCells4.75
CD105+_Endothelial4.9
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.1
CD34+6.1
CD4+_Tcells326.9
CD56+_NKCells583.5
CD71+_EarlyErythroid4.55
CD8+_Tcells583.3
CardiacMyocytes6.4
Caudatenucleus4.5
Cerebellum4
CerebellumPeduncles5.6
CiliaryGanglion3.45
CingulateCortex6.05
Colorectaladenocarcinoma4.85
DorsalRootGanglion3.75
FetalThyroid4.8
Fetalbrain5.05
Fetalliver4.3
Fetallung4.15
GlobusPallidus6
Heart6.3
Hypothalamus6.5
Kidney4.05
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)4.05
Liver6.55
Lung5.35
Lymphnode36.4
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)6.95
MedullaOblongata25.25
OccipitalLobe4.55
OlfactoryBulb3.9
Ovary3.3
Pancreas4
PancreaticIslet5.75
ParietalLobe5.25
Pituitary28.75
Placenta4.9
Pons7.7
PrefrontalCortex10.3
Prostate5.75
Salivarygland3.95
SkeletalMuscle6.25
Skin3.75
SmoothMuscle5.4
Spinalcord5.3
SubthalamicNucleus7.7
SuperiorCervicalGanglion6.55
TemporalLobe8.95
Testis5.35
TestisGermCell42.75
TestisIntersitial102.75
TestisLeydigCell19.5
TestisSeminiferousTubule28.75
Thalamus5.05
Thymus3.8
Thyroid5.95
Tongue4.8
Tonsil4.85
Trachea4.15
TrigeminalGanglion5.25
Uterus4
UterusCorpus7
WholeBlood67.7
Wholebrain5.7
colon5
pineal_day6.16
pineal_night6.24
retina5.975
small_intestine4.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P305198
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.71 ± 0.85
Basal Forebrain6.84 ± 0.26
Basal Part of Pons6.99 ± 0.36
Cerebellar Cortex5.33 ± 0.66
Cerebellar Nuclei6.85 ± 0.51
Claustrum6.85 ± 0.47
Epithalamus5.86 ± 0.64
Frontal Lobe6.12 ± 0.72
Globus Pallidus5.68 ± 1.37
Hypothalamus7.07 ± 0.39
Insula6.12 ± 0.49
Limbic Lobe5.91 ± 1.12
Mesencephalon6.57 ± 0.83
Myelencephalon6.29 ± 0.79
Occipital Lobe7.4 ± 0.51
Parietal Lobe6.83 ± 0.59
Pontine Tegmentum6.22 ± 0.98
Striatum5.91 ± 1.26
Subthalamus7.08 ± 0.22
Temporal Lobe6.29 ± 0.85
Thalamus6.31 ± 0.67
White Matter4.12 ± 1.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Stat4CBCerebellum1.47
2.9
Stat4CTXCerebral cortex1.63
2.12
Stat4HIPHippocampal region0.51
0.43
Stat4HPFHippocampal formation0.62
0.52
Stat4HYHypothalamus0.12
0.35
Stat4LSXLateral septal complex0.04
0
Stat4MBMidbrain0.55
0.99
Stat4MYMedulla1.28
1.38
Stat4OLFOlfactory bulb1.98
2.14
Stat4PPons0.47
0.67
Stat4PALPallidum0.12
0.18
Stat4RHPRetrohippocampal region0.86
0.7
Stat4sAMYStriatum-like amygdalar nuclei0.19
0.19
Stat4STRStriatum0.35
0.37
Stat4STRdStriatum dorsal region0.33
0.41
Stat4STRvStriatum ventral region0.42
0.3
Stat4THThalamus0.48
0.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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