AutismKB 2.0

Annotation Detail for STAT5A


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Basic Information Top
Gene Symbol:STAT5A ( MGF,STAT5 )
Gene Full Name: signal transducer and activator of transcription 5A
Band: 17q21.2
Quick LinksEntrez ID:6776; OMIM: 601511; Uniprot ID:STA5A_HUMAN; ENSEMBL ID: ENSG00000126561; HGNC ID: 11366
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia8 / 9584283
liver tumor6 / 9635962
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia7 / 9725071
normal119 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood9 / 12347872
bone7 / 7165597
bone marrow0 / 488010 
brain12 / 110098910
cervix4 / 4817183
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye9 / 21105442
heart4 / 8962644
intestine11 / 23447246
kidney6 / 21177728
larynx0 / 241450 
liver10 / 20774348
lung15 / 33697444
lymph0 / 442700 
lymph node16 / 91610174
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen4 / 5395274
stomach6 / 9661962
testis2 / 3304426
thymus16 / 81131197
thyroid2 / 4747342
tonsil4 / 16999235
trachea2 / 5241338
umbilical cord0 / 136800 
uterus13 / 23287855
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203010_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.2
Adipocyte7.2
AdrenalCortex3.7
Adrenalgland3.1
Amygdala3.9
Appendix3.65
AtrioventricularNode2.75
BDCA4+_DentriticCells4.25
Bonemarrow3.65
BronchialEpithelialCells3.65
CD105+_Endothelial10.75
CD14+_Monocytes16.85
CD19+_BCells(neg._sel.)9.85
CD33+_Myeloid11.2
CD34+41.85
CD4+_Tcells11.5
CD56+_NKCells5.2
CD71+_EarlyErythroid3.45
CD8+_Tcells10.5
CardiacMyocytes4.6
Caudatenucleus3.3
Cerebellum2.95
CerebellumPeduncles4.1
CiliaryGanglion2.55
CingulateCortex3.7
Colorectaladenocarcinoma3.7
DorsalRootGanglion2.8
FetalThyroid3.55
Fetalbrain3.65
Fetalliver3.15
Fetallung3.1
GlobusPallidus2.6
Heart4.6
Hypothalamus4.05
Kidney2.9
Leukemia_chronicMyelogenousK-5629.55
Leukemia_promyelocytic-HL-603.25
Leukemialymphoblastic(MOLT-4)81.25
Liver4.85
Lung4.9
Lymphnode5.65
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.1
MedullaOblongata3.35
OccipitalLobe3.3
OlfactoryBulb2.9
Ovary2.45
Pancreas2.95
PancreaticIslet3.95
ParietalLobe3.8
Pituitary4.3
Placenta3.85
Pons3.45
PrefrontalCortex4.6
Prostate4.35
Salivarygland2.9
SkeletalMuscle4.05
Skin2.95
SmoothMuscle4.15
Spinalcord3.9
SubthalamicNucleus3.3
SuperiorCervicalGanglion4
TemporalLobe3.3
Testis3.1
TestisGermCell3.05
TestisIntersitial3.05
TestisLeydigCell3.6
TestisSeminiferousTubule3.1
Thalamus3.65
Thymus3.95
Thyroid4.65
Tongue3.55
Tonsil3.6
Trachea3.1
TrigeminalGanglion3.65
Uterus3.9
UterusCorpus3.2
WholeBlood11.4
Wholebrain3.1
colon3.7
pineal_day4.58
pineal_night4.48
retina4.55
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P173088
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.32 ± 1.05
Basal Forebrain1.92 ± 0.22
Basal Part of Pons1.63 ± 0.31
Cerebellar Cortex1.94 ± 0.7
Cerebellar Nuclei2.3 ± 0.8
Claustrum2.72 ± 0.79
Epithalamus1.79 ± 0.68
Frontal Lobe1.76 ± 0.59
Globus Pallidus2.36 ± 0.52
Hypothalamus1.95 ± 0.57
Insula1.67 ± 0.45
Limbic Lobe1.87 ± 0.6
Mesencephalon2.08 ± 0.63
Myelencephalon1.99 ± 0.62
Occipital Lobe2.06 ± 0.86
Parietal Lobe1.98 ± 0.64
Pontine Tegmentum2.03 ± 0.85
Striatum2.11 ± 0.6
Subthalamus2.22 ± 0.57
Temporal Lobe1.89 ± 0.72
Thalamus1.9 ± 0.58
White Matter2.58 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Stat5aCBCerebellum16.87
29.25
Stat5aCTXCerebral cortex12.68
12.24
Stat5aHIPHippocampal region10.95
11.08
Stat5aHPFHippocampal formation11.23
10.2
Stat5aHYHypothalamus14.18
11.44
Stat5aLSXLateral septal complex1.14
1.26
Stat5aMBMidbrain11.43
12.94
Stat5aMYMedulla22.05
28.32
Stat5aOLFOlfactory bulb9.22
6.42
Stat5aPPons16.44
18.73
Stat5aPALPallidum1.69
1.64
Stat5aRHPRetrohippocampal region11.76
9
Stat5asAMYStriatum-like amygdalar nuclei8.56
5.78
Stat5aSTRStriatum3.15
2.96
Stat5aSTRdStriatum dorsal region2.49
2.77
Stat5aSTRvStriatum ventral region1.8
1.53
Stat5aTHThalamus12.06
9.72
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063139 13 72 84 AEHQVGEDGFLLK Peptide Atlas
STA5A_HUMAN_2 15 2 16 AGWIQAQQLQGDALR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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