AutismKB 2.0

Annotation Detail for STIM1


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Basic Information Top
Gene Symbol:STIM1 ( D11S4896E,GOK )
Gene Full Name: stromal interaction molecule 1
Band: 11p15.4
Quick LinksEntrez ID:6786; OMIM: 605921; Uniprot ID:STIM1_HUMAN; ENSEMBL ID: ENSG00000167323; HGNC ID: 11386
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult121 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma9 / 82823108
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor10 / 26384537
glioma10 / 10688393
head and neck tumor14 / 136302102
kidney tumor7 / 68959101
leukemia12 / 95842125
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal160 / 336030747
ovarian tumor2 / 7668226
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood12 / 12347897
bone4 / 7165555
bone marrow0 / 488010 
brain44 / 110098939
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye17 / 21105480
heart5 / 8962655
intestine11 / 23447246
kidney14 / 21177766
larynx1 / 2414541
liver4 / 20774319
lung20 / 33697459
lymph1 / 4427022
lymph node5 / 9161054
mammary gland5 / 15327132
mouth7 / 67052104
muscle3 / 10771527
nerve2 / 15768126
ovary3 / 10205129
pancreas17 / 21481279
parathyroid1 / 2053948
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta16 / 28082556
prostate10 / 18934552
salivary gland1 / 2015549
skin25 / 210574118
spleen2 / 5395237
stomach1 / 9661910
testis16 / 33044248
thymus14 / 81131172
thyroid3 / 4747363
tonsil4 / 16999235
trachea3 / 5241357
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202764_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.2
Adipocyte5.6
AdrenalCortex5.65
Adrenalgland4.55
Amygdala6.1
Appendix5.6
AtrioventricularNode4.35
BDCA4+_DentriticCells9.45
Bonemarrow6.65
BronchialEpithelialCells5.4
CD105+_Endothelial5.75
CD14+_Monocytes13.85
CD19+_BCells(neg._sel.)18.5
CD33+_Myeloid19.15
CD34+7.25
CD4+_Tcells15.7
CD56+_NKCells25.95
CD71+_EarlyErythroid6.55
CD8+_Tcells12.8
CardiacMyocytes6.9
Caudatenucleus13.5
Cerebellum5.7
CerebellumPeduncles6.3
CiliaryGanglion3.8
CingulateCortex9.35
Colorectaladenocarcinoma5.65
DorsalRootGanglion4.65
FetalThyroid5.5
Fetalbrain5.3
Fetalliver4.85
Fetallung4.75
GlobusPallidus13.55
Heart6.95
Hypothalamus5.7
Kidney5.2
Leukemia_chronicMyelogenousK-5629.3
Leukemia_promyelocytic-HL-604.85
Leukemialymphoblastic(MOLT-4)5.5
Liver7.35
Lung7
Lymphnode10.4
Lymphoma_burkitts(Daudi)8.5
Lymphoma_burkitts(Raji)12.45
MedullaOblongata4.85
OccipitalLobe5
OlfactoryBulb5
Ovary3.6
Pancreas4.45
PancreaticIslet5.95
ParietalLobe5.9
Pituitary6.4
Placenta9.6
Pons5.9
PrefrontalCortex7
Prostate5.9
Salivarygland6
SkeletalMuscle7.85
Skin4.15
SmoothMuscle6.3
Spinalcord6.1
SubthalamicNucleus5.55
SuperiorCervicalGanglion6.2
TemporalLobe5.1
Testis6.55
TestisGermCell7
TestisIntersitial4.7
TestisLeydigCell6
TestisSeminiferousTubule5.25
Thalamus5.8
Thymus8.75
Thyroid6.6
Tongue6.6
Tonsil5.2
Trachea7.65
TrigeminalGanglion5.3
Uterus4.55
UterusCorpus4.85
WholeBlood9.1
Wholebrain5.1
colon5.25
pineal_day9.58
pineal_night7.88
retina8.7
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16185_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.66 ± 1.11
Basal Forebrain2.11 ± 0.25
Basal Part of Pons2.09 ± 0.73
Cerebellar Cortex2.22 ± 0.77
Cerebellar Nuclei2.49 ± 0.7
Claustrum2.89 ± 0.72
Epithalamus2.09 ± 0.65
Frontal Lobe2.2 ± 0.72
Globus Pallidus2.37 ± 0.48
Hypothalamus2.28 ± 0.58
Insula2.24 ± 0.88
Limbic Lobe2.2 ± 0.63
Mesencephalon2.42 ± 0.75
Myelencephalon2.29 ± 0.66
Occipital Lobe2.33 ± 0.59
Parietal Lobe2.33 ± 0.81
Pontine Tegmentum2.38 ± 0.73
Striatum2.53 ± 0.79
Subthalamus2.4 ± 0.8
Temporal Lobe2.24 ± 0.68
Thalamus2.19 ± 0.68
White Matter2.57 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Stim1CBCerebellum33.11
93.82
Stim1CTXCerebral cortex100
100
Stim1HIPHippocampal region79.69
100
Stim1HPFHippocampal formation100
100
Stim1HYHypothalamus98.09
98.24
Stim1LSXLateral septal complex45.7
44.86
Stim1MBMidbrain86.64
94.68
Stim1MYMedulla61.72
92.83
Stim1OLFOlfactory bulb100
100
Stim1PPons75.19
100
Stim1PALPallidum96.37
100
Stim1RHPRetrohippocampal region100
100
Stim1sAMYStriatum-like amygdalar nuclei100
100
Stim1STRStriatum100
100
Stim1STRdStriatum dorsal region100
100
Stim1STRvStriatum ventral region100
100
Stim1THThalamus84.55
84.61
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000727 20 31 50 ATGTSSGANSEESTAAEFCR Peptide Atlas
STIM1_HUMAN_314 12 314 325 QKYAEEELEQVR PRIDE
STIM1_HUMAN_558 22 558 579 LIEGVHPGSLVEKLPDSPALAK PRIDE
STIM1_HUMAN_593 23 593 615 AHSLMELSPSAPPGGSPHLDSSR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018