AutismKB 2.0

Annotation Detail for STRN


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Basic Information Top
Gene Symbol:STRN ( MGC125642,SG2NA )
Gene Full Name: striatin, calmodulin binding protein
Band: 2p22.2
Quick LinksEntrez ID:6801; OMIM: NA; Uniprot ID:STRN_HUMAN; ENSEMBL ID: ENSG00000115808; HGNC ID: 11424
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal36 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone0 / 716550 
bone marrow1 / 4880120
brain8 / 11009897
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye3 / 21105414
heart2 / 8962622
intestine6 / 23447225
kidney1 / 2117774
larynx1 / 2414541
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205520_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.95
Adipocyte4.05
AdrenalCortex4.35
Adrenalgland3.5
Amygdala4.25
Appendix4.5
AtrioventricularNode3.55
BDCA4+_DentriticCells4.5
Bonemarrow4.2
BronchialEpithelialCells4.05
CD105+_Endothelial4.15
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.3
CD34+5.2
CD4+_Tcells4.4
CD56+_NKCells4.95
CD71+_EarlyErythroid3.85
CD8+_Tcells3.9
CardiacMyocytes5.25
Caudatenucleus3.7
Cerebellum3.3
CerebellumPeduncles4.65
CiliaryGanglion4.05
CingulateCortex4.2
Colorectaladenocarcinoma4.15
DorsalRootGanglion3.55
FetalThyroid4
Fetalbrain4.05
Fetalliver3.65
Fetallung3.35
GlobusPallidus3.05
Heart5.7
Hypothalamus4.4
Kidney3.55
Leukemia_chronicMyelogenousK-5623.7
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.25
Liver5.5
Lung4.55
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.35
Lymphoma_burkitts(Raji)5.9
MedullaOblongata3.7
OccipitalLobe3.65
OlfactoryBulb3.25
Ovary2.9
Pancreas3.3
PancreaticIslet4.4
ParietalLobe4.4
Pituitary4.75
Placenta4.2
Pons3.9
PrefrontalCortex5.2
Prostate4.75
Salivarygland3.35
SkeletalMuscle5.05
Skin3.5
SmoothMuscle4.65
Spinalcord4.4
SubthalamicNucleus3.75
SuperiorCervicalGanglion6
TemporalLobe3.85
Testis3.5
TestisGermCell3.4
TestisIntersitial4.4
TestisLeydigCell4.1
TestisSeminiferousTubule3.55
Thalamus4.2
Thymus3.2
Thyroid5.15
Tongue4.1
Tonsil4
Trachea3.4
TrigeminalGanglion5.3
Uterus3.35
UterusCorpus3.8
WholeBlood4.5
Wholebrain3.4
colon4.15
pineal_day5.12
pineal_night5.04
retina4.95
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P120863
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.89 ± 0.38
Basal Forebrain6.7 ± 0.12
Basal Part of Pons6.93 ± 0.24
Cerebellar Cortex6.66 ± 0.1
Cerebellar Nuclei6.75 ± 0.4
Claustrum6.94 ± 0.37
Epithalamus6.45 ± 0.53
Frontal Lobe6.73 ± 0.32
Globus Pallidus6.79 ± 0.27
Hypothalamus6.45 ± 0.31
Insula6.66 ± 0.26
Limbic Lobe6.98 ± 0.33
Mesencephalon6.81 ± 0.39
Myelencephalon6.78 ± 0.37
Occipital Lobe6.99 ± 0.29
Parietal Lobe6.84 ± 0.37
Pontine Tegmentum6.86 ± 0.42
Striatum8.03 ± 0.56
Subthalamus6.91 ± 0.36
Temporal Lobe6.71 ± 0.25
Thalamus6.71 ± 0.31
White Matter7.28 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
StrnCBCerebellum13.12
16.36
StrnCTXCerebral cortex41.69
33.97
StrnHIPHippocampal region36.44
58.89
StrnHPFHippocampal formation35.02
45.08
StrnHYHypothalamus5.59
4.81
StrnLSXLateral septal complex23.86
23.31
StrnMBMidbrain14.58
14.84
StrnMYMedulla16.91
22.12
StrnOLFOlfactory bulb29.38
25.21
StrnPPons16.04
19.26
StrnPALPallidum19.99
22.39
StrnRHPRetrohippocampal region34.32
30.64
StrnsAMYStriatum-like amygdalar nuclei12.89
10.72
StrnSTRStriatum100
100
StrnSTRdStriatum dorsal region100
100
StrnSTRvStriatum ventral region100
100
StrnTHThalamus10.29
9.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009762 13 765 777 CYIASAGADALAK Peptide Atlas
STRN_HUMAN_354 9 354 362 LQDMLANLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018