Annotation Detail for STX4
Basic Information Top
| Gene Symbol: | STX4 ( STX4A,p35-2 ) |
|---|---|
| Gene Full Name: | syntaxin 4 |
| Band: | 16p11.2 |
| Quick Links | Entrez ID:6810; OMIM: 186591; Uniprot ID:STX4_HUMAN; ENSEMBL ID: ENSG00000103496; HGNC ID: 11439 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.83734
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 14 / 564012 | 24 | |
| neonate | 2 / 31097 | 64 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 120 / 1939121 | 61 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 10 / 82823 | 120 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 8 / 119369 | 67 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 13 / 136302 | 95 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 10 / 103127 | 96 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 1 / 97250 | 10 |  |
| normal | 118 / 3360307 | 35 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 15 / 125191 | 119 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 10 / 123478 | 80 | |
| bone | 9 / 71655 | 125 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 28 / 1100989 | 25 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 9 / 215722 | 41 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 12 / 211054 | 56 | |
| heart | 1 / 89626 | 11 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 10 / 24145 | 414 |  |
| liver | 9 / 207743 | 43 | |
| lung | 39 / 336974 | 115 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 13 / 189345 | 68 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 8 / 210574 | 37 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 4 / 96619 | 41 | |
| testis | 2 / 330442 | 6 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203530_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 34.2 | |
| Adipocyte | 5.8 | |
| AdrenalCortex | 10.95 | |
| Adrenalgland | 5.7 | |
| Amygdala | 5.7 | |
| Appendix | 5.2 | |
| AtrioventricularNode | 3.95 | |
| BDCA4+_DentriticCells | 46.35 | |
| Bonemarrow | 5.7 | |
| BronchialEpithelialCells | 17.55 | |
| CD105+_Endothelial | 12.8 | |
| CD14+_Monocytes | 28.25 | |
| CD19+_BCells(neg._sel.) | 25.9 | |
| CD33+_Myeloid | 42.6 | |
| CD34+ | 17.3 | |
| CD4+_Tcells | 51.65 | |
| CD56+_NKCells | 114.85 | |
| CD71+_EarlyErythroid | 18.05 | |
| CD8+_Tcells | 51.3 | |
| CardiacMyocytes | 8.5 | |
| Caudatenucleus | 4.85 | |
| Cerebellum | 4.05 | |
| CerebellumPeduncles | 5.75 | |
| CiliaryGanglion | 3.8 | |
| CingulateCortex | 5.9 | |
| Colorectaladenocarcinoma | 8.15 | |
| DorsalRootGanglion | 3.65 | |
| FetalThyroid | 6.6 | |
| Fetalbrain | 5.8 | |
| Fetalliver | 4.6 | |
| Fetallung | 6.7 | |
| GlobusPallidus | 3.9 | |
| Heart | 7.3 | |
| Hypothalamus | 12.95 | |
| Kidney | 4.3 | |
| Leukemia_chronicMyelogenousK-562 | 5.3 | |
| Leukemia_promyelocytic-HL-60 | 4.7 | |
| Leukemialymphoblastic(MOLT-4) | 4.9 | |
| Liver | 7.6 | |
| Lung | 49.3 | |
| Lymphnode | 10.3 | |
| Lymphoma_burkitts(Daudi) | 6.9 | |
| Lymphoma_burkitts(Raji) | 8.1 | |
| MedullaOblongata | 5.5 | |
| OccipitalLobe | 5.3 | |
| OlfactoryBulb | 7.1 | |
| Ovary | 3.7 | |
| Pancreas | 4.7 | |
| PancreaticIslet | 6.3 | |
| ParietalLobe | 6.1 | |
| Pituitary | 5.7 | |
| Placenta | 15.65 | |
| Pons | 5.5 | |
| PrefrontalCortex | 7.35 | |
| Prostate | 8.9 | |
| Salivarygland | 3.5 | |
| SkeletalMuscle | 6.3 | |
| Skin | 3.9 | |
| SmoothMuscle | 10.2 | |
| Spinalcord | 7.4 | |
| SubthalamicNucleus | 4.85 | |
| SuperiorCervicalGanglion | 6.2 | |
| TemporalLobe | 5.15 | |
| Testis | 5.05 | |
| TestisGermCell | 4.95 | |
| TestisIntersitial | 4.2 | |
| TestisLeydigCell | 5.25 | |
| TestisSeminiferousTubule | 4.45 | |
| Thalamus | 5.95 | |
| Thymus | 6.1 | |
| Thyroid | 8.9 | |
| Tongue | 5.6 | |
| Tonsil | 5.8 | |
| Trachea | 4.85 | |
| TrigeminalGanglion | 5.35 | |
| Uterus | 4.95 | |
| UterusCorpus | 5.15 | |
| WholeBlood | 27.6 | |
| Wholebrain | 5.3 | |
| colon | 11.05 | |
| pineal_day | 17.28 | |
| pineal_night | 22 | |
| retina | 8.425 | |
| small_intestine | 10.15 | |
- Probe name: A_23_P61646
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.3 ± 0.44 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.25 ± 0.35 | |
| Basal Part of Pons | 5.42 ± 0.45 | |
| Cerebellar Cortex | 4.89 ± 0.41 | |
| Cerebellar Nuclei | 5.41 ± 0.5 | |
| Claustrum | 5.14 ± 0.83 | |
| Epithalamus | 5.03 ± 0.43 | |
| Frontal Lobe | 5.24 ± 0.43 | |
| Globus Pallidus | 5.78 ± 0.36 | |
| Hypothalamus | 5.06 ± 0.34 | |
| Insula | 5.24 ± 0.33 | |
| Limbic Lobe | 5.09 ± 0.52 | |
| Mesencephalon | 5.09 ± 0.49 | |
| Myelencephalon | 5.09 ± 0.49 | |
| Occipital Lobe | 4.63 ± 0.39 | |
| Parietal Lobe | 4.99 ± 0.39 | |
| Pontine Tegmentum | 5.03 ± 0.5 | |
| Striatum | 4.9 ± 0.43 | |
| Subthalamus | 4.89 ± 0.54 | |
| Temporal Lobe | 5.21 ± 0.41 | |
| Thalamus | 4.99 ± 0.46 | |
| White Matter | 6.4 ± 0.18 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Stx4a | CB | Cerebellum | 35.64 | |
| 68.69 | | |||
| Stx4a | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Stx4a | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Stx4a | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Stx4a | HY | Hypothalamus | 69.4 | |
| 75.96 | | |||
| Stx4a | LSX | Lateral septal complex | 100 | |
| 95.34 | | |||
| Stx4a | MB | Midbrain | 55.89 | |
| 68.08 | | |||
| Stx4a | MY | Medulla | 34.61 | |
| 55.67 | | |||
| Stx4a | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Stx4a | P | Pons | 40.64 | |
| 64.49 | | |||
| Stx4a | PAL | Pallidum | 85.68 | |
| 97.62 | | |||
| Stx4a | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Stx4a | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Stx4a | STR | Striatum | 100 | |
| 100 | | |||
| Stx4a | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Stx4a | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Stx4a | TH | Thalamus | 84.73 | |
| 95.09 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00032319 | 19 | 103 | 121 | AIEPQKEEADENYNSVNTR | Peptide Atlas |
| STX4_HUMAN_102 | 19 | 102 | 120 | AIEPQKEEADENYNSVNTR | PRIDE |
| STX4_HUMAN_198 | 9 | 198 | 206 | QALNEISAR | PRIDE |