AutismKB 2.0

Annotation Detail for SUPT6H


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Basic Information Top
Gene Symbol:SUPT6H ( KIAA0162,MGC87943,SPT6,SPT6H,emb-5 )
Gene Full Name: suppressor of Ty 6 homolog (S. cerevisiae)
Band: 17q11.2
Quick LinksEntrez ID:6830; OMIM: 601333; Uniprot ID:SPT6H_HUMAN; ENSEMBL ID: ENSG00000109111; HGNC ID: 11470
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst8 / 62319128
fetus38 / 56401267
neonate2 / 3109764
infant0 / 236200 
juvenile5 / 5555689
adult203 / 1939121104
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor19 / 94178201
cervical tumor4 / 34366116
chondrosarcoma14 / 82823169
colorectal tumor25 / 114246218
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor16 / 26384560
glioma9 / 10688384
head and neck tumor11 / 13630280
kidney tumor8 / 68959116
leukemia11 / 95842114
liver tumor9 / 9635993
lung tumor24 / 103127232
lymphoma5 / 7175569
non-neoplasia6 / 9725061
normal228 / 336030767
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma8 / 46356172
skin tumor21 / 124949168
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood9 / 12347872
bone5 / 7165569
bone marrow1 / 4880120
brain80 / 110098972
cervix4 / 4817183
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye29 / 211054137
heart4 / 8962644
intestine35 / 234472149
kidney30 / 211777141
larynx1 / 2414541
liver11 / 20774352
lung55 / 336974163
lymph3 / 4427067
lymph node8 / 9161087
mammary gland22 / 153271143
mouth7 / 67052104
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta17 / 28082560
prostate7 / 18934536
salivary gland1 / 2015549
skin24 / 210574113
spleen3 / 5395255
stomach3 / 9661931
testis15 / 33044245
thymus7 / 8113186
thyroid5 / 47473105
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord8 / 13680584
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208830_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.4
Adipocyte42.4
AdrenalCortex29.75
Adrenalgland30.1
Amygdala18.5
Appendix14.75
AtrioventricularNode14.05
BDCA4+_DentriticCells37.6
Bonemarrow16.95
BronchialEpithelialCells15.4
CD105+_Endothelial22.15
CD14+_Monocytes17.1
CD19+_BCells(neg._sel.)23.5
CD33+_Myeloid32.8
CD34+16.65
CD4+_Tcells42.5
CD56+_NKCells17.6
CD71+_EarlyErythroid16.9
CD8+_Tcells21.45
CardiacMyocytes21.35
Caudatenucleus20.3
Cerebellum19.15
CerebellumPeduncles19
CiliaryGanglion10.3
CingulateCortex19.15
Colorectaladenocarcinoma37.75
DorsalRootGanglion13.65
FetalThyroid33.95
Fetalbrain15.45
Fetalliver16.65
Fetallung12.3
GlobusPallidus18.2
Heart17.95
Hypothalamus16.7
Kidney29.45
Leukemia_chronicMyelogenousK-56234.85
Leukemia_promyelocytic-HL-6018.6
Leukemialymphoblastic(MOLT-4)55.8
Liver18.45
Lung48.8
Lymphnode18.55
Lymphoma_burkitts(Daudi)18.3
Lymphoma_burkitts(Raji)30
MedullaOblongata16.75
OccipitalLobe13.45
OlfactoryBulb13
Ovary10
Pancreas10
PancreaticIslet31.8
ParietalLobe39.85
Pituitary57.35
Placenta52.55
Pons18.55
PrefrontalCortex22.7
Prostate28.25
Salivarygland13.4
SkeletalMuscle24.35
Skin20.05
SmoothMuscle76.85
Spinalcord15.9
SubthalamicNucleus18.15
SuperiorCervicalGanglion19.65
TemporalLobe12.85
Testis13
TestisGermCell16.3
TestisIntersitial11.95
TestisLeydigCell14.05
TestisSeminiferousTubule12.25
Thalamus14.45
Thymus38.95
Thyroid36.3
Tongue14.6
Tonsil15.8
Trachea21.85
TrigeminalGanglion13.85
Uterus30.15
UterusCorpus27.35
WholeBlood30.9
Wholebrain16.5
colon14.45
pineal_day36.96
pineal_night31.08
retina49.4
small_intestine13.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P126873
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.31 ± 0.7
Basal Forebrain3.06 ± 0.43
Basal Part of Pons3.05 ± 0.51
Cerebellar Cortex3.42 ± 0.44
Cerebellar Nuclei3.16 ± 0.44
Claustrum3.23 ± 0.63
Epithalamus3.02 ± 0.67
Frontal Lobe3.2 ± 0.62
Globus Pallidus3.5 ± 0.61
Hypothalamus3.05 ± 0.5
Insula3.21 ± 0.47
Limbic Lobe3.14 ± 0.55
Mesencephalon3.34 ± 0.63
Myelencephalon3.22 ± 0.51
Occipital Lobe3.12 ± 0.51
Parietal Lobe3.19 ± 0.51
Pontine Tegmentum3.24 ± 0.57
Striatum3.21 ± 0.61
Subthalamus3.45 ± 0.29
Temporal Lobe3.19 ± 0.51
Thalamus3.26 ± 0.57
White Matter3.12 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Supt6hCBCerebellum30.62
62.49
Supt6hCTXCerebral cortex100
100
Supt6hHIPHippocampal region100
100
Supt6hHPFHippocampal formation100
100
Supt6hHYHypothalamus72.01
63.14
Supt6hLSXLateral septal complex100
100
Supt6hMBMidbrain54.82
55.26
Supt6hMYMedulla55.36
67.68
Supt6hOLFOlfactory bulb100
100
Supt6hPPons52.52
62.37
Supt6hPALPallidum64.78
63.16
Supt6hRHPRetrohippocampal region100
100
Supt6hsAMYStriatum-like amygdalar nuclei84.63
71.09
Supt6hSTRStriatum97.35
82.08
Supt6hSTRdStriatum dorsal region90.76
76.91
Supt6hSTRvStriatum ventral region100
96.19
Supt6hTHThalamus77.55
74.1
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024109 20 976 995 AIAHPYSQALIQYVCGLGPR Peptide Atlas
SPT6H_HUMAN_1346 17 1346 1362 MMETMDQGDVIIRPSSK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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