AutismKB 2.0

Annotation Detail for VAMP1


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Basic Information Top
Gene Symbol:VAMP1 ( DKFZp686H12131,SYB1,VAMP-1 )
Gene Full Name: vesicle-associated membrane protein 1 (synaptobrevin 1)
Band: 12p13.31
Quick LinksEntrez ID:6843; OMIM: 185880; Uniprot ID:VAMP1_HUMAN; ENSEMBL ID: ENSG00000139190; HGNC ID: 12642
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus28 / 56401249
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult92 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor20 / 26384575
glioma6 / 10688356
head and neck tumor5 / 13630236
kidney tumor24 / 68959348
leukemia22 / 95842229
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia15 / 97250154
normal286 / 336030785
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder1 / 2975733
blood15 / 123478121
bone3 / 7165541
bone marrow0 / 488010 
brain186 / 1100989168
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye9 / 21105442
heart8 / 8962689
intestine6 / 23447225
kidney25 / 211777118
larynx1 / 2414541
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node16 / 91610174
mammary gland2 / 15327113
mouth3 / 6705244
muscle0 / 1077150 
nerve4 / 15768253
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin4 / 21057418
spleen13 / 53952240
stomach3 / 9661931
testis18 / 33044254
thymus90 / 811311109
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207101_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.15
Adipocyte9.35
AdrenalCortex11.2
Adrenalgland8.55
Amygdala11.4
Appendix11.55
AtrioventricularNode9.95
BDCA4+_DentriticCells9.55
Bonemarrow9.9
BronchialEpithelialCells9.15
CD105+_Endothelial10
CD14+_Monocytes10.5
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid10.75
CD34+13.9
CD4+_Tcells17.15
CD56+_NKCells10.35
CD71+_EarlyErythroid9.45
CD8+_Tcells10.85
CardiacMyocytes22.55
Caudatenucleus8.9
Cerebellum8
CerebellumPeduncles12.2
CiliaryGanglion6.85
CingulateCortex10.35
Colorectaladenocarcinoma10
DorsalRootGanglion9.05
FetalThyroid9.6
Fetalbrain9.5
Fetalliver8.9
Fetallung7.15
GlobusPallidus7.45
Heart21.65
Hypothalamus9.35
Kidney9.1
Leukemia_chronicMyelogenousK-5628.45
Leukemia_promyelocytic-HL-6012.1
Leukemialymphoblastic(MOLT-4)7.35
Liver13.25
Lung10.75
Lymphnode7.8
Lymphoma_burkitts(Daudi)20.2
Lymphoma_burkitts(Raji)17.5
MedullaOblongata8.75
OccipitalLobe9.2
OlfactoryBulb7.05
Ovary7.4
Pancreas7.9
PancreaticIslet10.55
ParietalLobe16.8
Pituitary11.6
Placenta9.45
Pons9.7
PrefrontalCortex12
Prostate11.6
Salivarygland8.05
SkeletalMuscle17.15
Skin9.15
SmoothMuscle10.95
Spinalcord10.35
SubthalamicNucleus9.7
SuperiorCervicalGanglion16.8
TemporalLobe8.95
Testis7.8
TestisGermCell7.95
TestisIntersitial8.25
TestisLeydigCell10.15
TestisSeminiferousTubule8.3
Thalamus10.2
Thymus6.8
Thyroid12.65
Tongue10.95
Tonsil9.55
Trachea7.8
TrigeminalGanglion11.05
Uterus7.8
UterusCorpus8.85
WholeBlood10.15
Wholebrain8.2
colon10
pineal_day12.42
pineal_night12.74
retina11.65
small_intestine9.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10885_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.33 ± 0.56
Basal Forebrain7.84 ± 0.54
Basal Part of Pons8.52 ± 0.49
Cerebellar Cortex7.27 ± 0.53
Cerebellar Nuclei9.71 ± 0.41
Claustrum7.86 ± 0.64
Epithalamus6.75 ± 0.74
Frontal Lobe7.88 ± 0.93
Globus Pallidus9.74 ± 0.44
Hypothalamus7.91 ± 0.74
Insula7.15 ± 0.42
Limbic Lobe7.58 ± 0.73
Mesencephalon8.24 ± 0.86
Myelencephalon7.96 ± 0.75
Occipital Lobe8.84 ± 0.66
Parietal Lobe8.42 ± 0.71
Pontine Tegmentum8.2 ± 0.72
Striatum7.32 ± 0.75
Subthalamus8.79 ± 0.15
Temporal Lobe7.47 ± 0.72
Thalamus8.2 ± 0.81
White Matter8.44 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Vamp1CBCerebellum92.08
100
Vamp1CTXCerebral cortex98.22
99.75
Vamp1HIPHippocampal region58.43
90.87
Vamp1HPFHippocampal formation72.1
86.19
Vamp1HYHypothalamus87.46
100
Vamp1LSXLateral septal complex57.32
33.2
Vamp1MBMidbrain100
100
Vamp1MYMedulla100
100
Vamp1OLFOlfactory bulb82.86
69.84
Vamp1PPons99.68
100
Vamp1PALPallidum77.6
100
Vamp1RHPRetrohippocampal region91.67
81.71
Vamp1sAMYStriatum-like amygdalar nuclei73.64
63.57
Vamp1STRStriatum29.75
21.96
Vamp1STRdStriatum dorsal region19.11
13.27
Vamp1STRvStriatum ventral region34.25
26.85
Vamp1THThalamus88.06
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
VAMP1_HUMAN_49 12 49 60 VNVDKVLERDQK PRIDE
VAMP1_HUMAN_49 9 49 57 VNVDKVLER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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