AutismKB 2.0

Annotation Detail for SYN2


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Basic Information Top
Gene Symbol:SYN2 ( SYNII,SYNIIa,SYNIIb )
Gene Full Name: synapsin II
Band: 3p25.2
Quick LinksEntrez ID:6854; OMIM: 600755; Uniprot ID:Q86VA8_HUMAN; ENSEMBL ID: ENSG00000157152; HGNC ID: 11495
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate2 / 3109764
infant1 / 2362042
juvenile4 / 5555671
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal101 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain100 / 110098990
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve3 / 15768190
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210247_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte36.35
AdrenalCortex6.15
Adrenalgland4.8
Amygdala121.15
Appendix6.15
AtrioventricularNode4.55
BDCA4+_DentriticCells5.4
Bonemarrow5.75
BronchialEpithelialCells5.45
CD105+_Endothelial5.45
CD14+_Monocytes5.8
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid6.85
CD34+6.85
CD4+_Tcells5.75
CD56+_NKCells6.75
CD71+_EarlyErythroid5.3
CD8+_Tcells4.9
CardiacMyocytes7.55
Caudatenucleus8.85
Cerebellum54.9
CerebellumPeduncles19.25
CiliaryGanglion5
CingulateCortex27.1
Colorectaladenocarcinoma5.75
DorsalRootGanglion6.1
FetalThyroid5.5
Fetalbrain5.95
Fetalliver5
Fetallung4.4
GlobusPallidus9
Heart7.55
Hypothalamus13.35
Kidney4.7
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)4.6
Liver7.6
Lung6.25
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)8.1
MedullaOblongata11.2
OccipitalLobe25.4
OlfactoryBulb4.6
Ovary3.8
Pancreas4.6
PancreaticIslet6.1
ParietalLobe14
Pituitary7.65
Placenta5.8
Pons5.7
PrefrontalCortex40
Prostate7
Salivarygland4.8
SkeletalMuscle6.85
Skin4.35
SmoothMuscle5.95
Spinalcord12.25
SubthalamicNucleus15.5
SuperiorCervicalGanglion6.9
TemporalLobe21.25
Testis9.5
TestisGermCell7
TestisIntersitial4.9
TestisLeydigCell5.7
TestisSeminiferousTubule5.35
Thalamus13.7
Thymus4.3
Thyroid7.25
Tongue5.6
Tonsil5.55
Trachea4.8
TrigeminalGanglion6.5
Uterus4.5
UterusCorpus5.15
WholeBlood6.2
Wholebrain52.85
colon5.75
pineal_day6.98
pineal_night6.6
retina7
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_620_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.1 ± 0.41
Basal Forebrain7.71 ± 0.41
Basal Part of Pons8.99 ± 0.25
Cerebellar Cortex7.9 ± 0.32
Cerebellar Nuclei7.18 ± 0.48
Claustrum8.59 ± 0.31
Epithalamus6.6 ± 0.93
Frontal Lobe8.16 ± 0.54
Globus Pallidus5.94 ± 0.87
Hypothalamus7.54 ± 0.55
Insula8.43 ± 0.34
Limbic Lobe8.62 ± 0.7
Mesencephalon7.62 ± 0.87
Myelencephalon8.01 ± 0.76
Occipital Lobe7.69 ± 0.92
Parietal Lobe8.21 ± 0.78
Pontine Tegmentum8.01 ± 0.6
Striatum7.25 ± 1.02
Subthalamus7.89 ± 0.35
Temporal Lobe8.52 ± 0.42
Thalamus7.9 ± 0.47
White Matter5.6 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Syn2CBCerebellum60.54
91.99
Syn2CTXCerebral cortex100
100
Syn2HIPHippocampal region100
100
Syn2HPFHippocampal formation100
100
Syn2HYHypothalamus100
100
Syn2LSXLateral septal complex88.1
89.52
Syn2MBMidbrain94.3
100
Syn2MYMedulla74.47
100
Syn2OLFOlfactory bulb100
100
Syn2PPons79.87
100
Syn2PALPallidum87.36
100
Syn2RHPRetrohippocampal region100
100
Syn2sAMYStriatum-like amygdalar nuclei100
100
Syn2STRStriatum97.55
100
Syn2STRdStriatum dorsal region78.69
73.89
Syn2STRvStriatum ventral region100
100
Syn2THThalamus76.39
99.66
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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