AutismKB 2.0

Annotation Detail for SYP


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Basic Information Top
Gene Symbol:SYP ( MRXSYP )
Gene Full Name: synaptophysin
Band: Xp11.23
Quick LinksEntrez ID:6855; OMIM: 313475; Uniprot ID:SYPH_HUMAN; ENSEMBL ID: ENSG00000102003; HGNC ID: 11506
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor15 / 26384556
glioma8 / 10688374
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia14 / 97250143
normal263 / 336030778
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer1 / 1026809
retinoblastoma9 / 46356194
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain254 / 1100989230
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye28 / 211054132
heart0 / 896260 
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213200_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.6
Adipocyte14.8
AdrenalCortex22.7
Adrenalgland14.35
Amygdala33.6
Appendix15.2
AtrioventricularNode12.95
BDCA4+_DentriticCells12.9
Bonemarrow15.1
BronchialEpithelialCells9.55
CD105+_Endothelial13.2
CD14+_Monocytes14.1
CD19+_BCells(neg._sel.)14.25
CD33+_Myeloid17.7
CD34+13.85
CD4+_Tcells16.25
CD56+_NKCells17.15
CD71+_EarlyErythroid13.9
CD8+_Tcells11.55
CardiacMyocytes20.1
Caudatenucleus27.3
Cerebellum57.4
CerebellumPeduncles48.7
CiliaryGanglion11.75
CingulateCortex65.2
Colorectaladenocarcinoma15.1
DorsalRootGanglion16.3
FetalThyroid13.55
Fetalbrain28.1
Fetalliver12.35
Fetallung12.2
GlobusPallidus42.9
Heart18.2
Hypothalamus60.55
Kidney12.45
Leukemia_chronicMyelogenousK-56213.6
Leukemia_promyelocytic-HL-6012.7
Leukemialymphoblastic(MOLT-4)11.75
Liver19.3
Lung14.05
Lymphnode11.45
Lymphoma_burkitts(Daudi)18.8
Lymphoma_burkitts(Raji)21.4
MedullaOblongata36.4
OccipitalLobe69.65
OlfactoryBulb11.85
Ovary9.95
Pancreas12.85
PancreaticIslet19.85
ParietalLobe75.95
Pituitary25.2
Placenta14.8
Pons39.45
PrefrontalCortex155.8
Prostate15.4
Salivarygland12.45
SkeletalMuscle19.9
Skin14.7
SmoothMuscle15.15
Spinalcord32
SubthalamicNucleus45.4
SuperiorCervicalGanglion17.4
TemporalLobe69.95
Testis12.7
TestisGermCell11.3
TestisIntersitial14
TestisLeydigCell14.6
TestisSeminiferousTubule13
Thalamus88
Thymus8.95
Thyroid16.15
Tongue15.55
Tonsil14.3
Trachea11.75
TrigeminalGanglion15.55
Uterus10.2
UterusCorpus13.6
WholeBlood11.9
Wholebrain98.7
colon13.7
pineal_day1231.72
pineal_night1331.72
retina26.9
small_intestine13.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14348_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.37 ± 0.4
Basal Forebrain7.68 ± 0.43
Basal Part of Pons8.48 ± 0.53
Cerebellar Cortex8.26 ± 0.24
Cerebellar Nuclei7.41 ± 0.6
Claustrum8.17 ± 0.49
Epithalamus6.17 ± 0.94
Frontal Lobe7.93 ± 0.5
Globus Pallidus6.84 ± 0.41
Hypothalamus7.4 ± 0.54
Insula7.94 ± 0.44
Limbic Lobe8.32 ± 0.48
Mesencephalon7.79 ± 0.6
Myelencephalon7.84 ± 0.66
Occipital Lobe7.77 ± 0.39
Parietal Lobe8.09 ± 0.68
Pontine Tegmentum7.64 ± 0.41
Striatum6.68 ± 0.6
Subthalamus7.73 ± 0.46
Temporal Lobe8.17 ± 0.39
Thalamus7.73 ± 0.43
White Matter6.21 ± 0.74
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00073120 12 77 88 LHQVYFDAPTCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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