AutismKB 2.0

Annotation Detail for SYT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SYT1 ( DKFZp781D2042,P65,SVP65,SYT )
Gene Full Name: synaptotagmin I
Band: 12q21.2
Quick LinksEntrez ID:6857; OMIM: 185605; Uniprot ID:SYT1_HUMAN; ENSEMBL ID: ENSG00000067715; HGNC ID: 11509
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus58 / 564012102
neonate0 / 310970 
infant3 / 23620127
juvenile9 / 55556161
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor14 / 68959203
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia15 / 97250154
normal334 / 336030799
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain326 / 1100989296
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye21 / 21105499
heart0 / 896260 
intestine1 / 2344724
kidney14 / 21177766
larynx2 / 2414582
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle4 / 10771537
nerve9 / 15768570
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203998_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.1
Adipocyte7.3
AdrenalCortex9.5
Adrenalgland6.65
Amygdala1522.75
Appendix9.15
AtrioventricularNode7.8
BDCA4+_DentriticCells7.3
Bonemarrow8.4
BronchialEpithelialCells7.1
CD105+_Endothelial7.4
CD14+_Monocytes7.95
CD19+_BCells(neg._sel.)7.6
CD33+_Myeloid9.05
CD34+8.95
CD4+_Tcells7.6
CD56+_NKCells8.3
CD71+_EarlyErythroid7.15
CD8+_Tcells6.65
CardiacMyocytes15.55
Caudatenucleus23.3
Cerebellum88.4
CerebellumPeduncles343.6
CiliaryGanglion7
CingulateCortex826.85
Colorectaladenocarcinoma7.45
DorsalRootGanglion6.9
FetalThyroid7.45
Fetalbrain127.6
Fetalliver6.6
Fetallung5.55
GlobusPallidus421.85
Heart12.75
Hypothalamus355.15
Kidney6.75
Leukemia_chronicMyelogenousK-5626.6
Leukemia_promyelocytic-HL-606.55
Leukemialymphoblastic(MOLT-4)5.7
Liver11.8
Lung8.1
Lymphnode6
Lymphoma_burkitts(Daudi)9.9
Lymphoma_burkitts(Raji)11.9
MedullaOblongata324
OccipitalLobe1395.85
OlfactoryBulb5.75
Ovary5.6
Pancreas6.6
PancreaticIslet8.05
ParietalLobe812.9
Pituitary8.7
Placenta7.3
Pons221.05
PrefrontalCortex318.65
Prostate8.4
Salivarygland6.3
SkeletalMuscle11.35
Skin7.25
SmoothMuscle8.4
Spinalcord8
SubthalamicNucleus584.75
SuperiorCervicalGanglion13.65
TemporalLobe224.5
Testis6.35
TestisGermCell5.95
TestisIntersitial6.4
TestisLeydigCell7.85
TestisSeminiferousTubule6.3
Thalamus57.55
Thymus5.45
Thyroid8.85
Tongue8.4
Tonsil7.45
Trachea6.1
TrigeminalGanglion9.7
Uterus11.4
UterusCorpus7.75
WholeBlood7.95
Wholebrain896.6
colon7.35
pineal_day615.68
pineal_night693.66
retina9.075
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_631_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.4 ± 0.51
Basal Forebrain11.91 ± 0.31
Basal Part of Pons13.42 ± 0.32
Cerebellar Cortex12.53 ± 0.23
Cerebellar Nuclei10.13 ± 0.93
Claustrum12.86 ± 0.28
Epithalamus10.87 ± 1.05
Frontal Lobe12.56 ± 0.6
Globus Pallidus9.87 ± 1
Hypothalamus11.76 ± 0.88
Insula12.6 ± 0.38
Limbic Lobe12.6 ± 0.73
Mesencephalon11.94 ± 1.02
Myelencephalon12.12 ± 0.99
Occipital Lobe11.69 ± 0.94
Parietal Lobe12.39 ± 0.7
Pontine Tegmentum11.84 ± 0.83
Striatum10.66 ± 0.91
Subthalamus11.85 ± 0.4
Temporal Lobe12.67 ± 0.47
Thalamus12.5 ± 0.44
White Matter9.61 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Syt1CBCerebellum100
100
Syt1CTXCerebral cortex100
100
Syt1HIPHippocampal region100
100
Syt1HPFHippocampal formation100
100
Syt1HYHypothalamus100
100
Syt1LSXLateral septal complex100
100
Syt1MBMidbrain100
100
Syt1MYMedulla100
100
Syt1OLFOlfactory bulb100
100
Syt1PPons100
100
Syt1PALPallidum100
100
Syt1RHPRetrohippocampal region100
100
Syt1sAMYStriatum-like amygdalar nuclei100
100
Syt1STRStriatum100
100
Syt1STRdStriatum dorsal region100
100
Syt1STRvStriatum ventral region100
100
Syt1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072908 9 274 282 LGDICFSLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved