AutismKB 2.0

Annotation Detail for SYT4


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Basic Information Top
Gene Symbol:SYT4 ( HsT1192,KIAA1342 )
Gene Full Name: synaptotagmin IV
Band: 18q12.3
Quick LinksEntrez ID:6860; OMIM: 600103; Uniprot ID:SYT4_HUMAN; ENSEMBL ID: ENSG00000132872; HGNC ID: 11512
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus132 / 564012234
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor39 / 263845147
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal557 / 3360307165
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain553 / 1100989502
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle7 / 10771564
nerve3 / 15768190
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis31 / 33044293
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10907_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.22 ± 0.44
Basal Forebrain9.94 ± 0.33
Basal Part of Pons10.24 ± 0.51
Cerebellar Cortex10.75 ± 0.18
Cerebellar Nuclei9.09 ± 0.65
Claustrum10.78 ± 0.57
Epithalamus9.73 ± 0.53
Frontal Lobe10.28 ± 0.55
Globus Pallidus8.37 ± 0.64
Hypothalamus10.86 ± 0.33
Insula10.27 ± 0.28
Limbic Lobe10.52 ± 0.53
Mesencephalon10.25 ± 0.93
Myelencephalon10.2 ± 0.69
Occipital Lobe10.39 ± 0.47
Parietal Lobe10.1 ± 0.57
Pontine Tegmentum10.15 ± 0.65
Striatum9.93 ± 0.38
Subthalamus10.15 ± 0.76
Temporal Lobe10.18 ± 0.43
Thalamus10.29 ± 0.4
White Matter7.7 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Syt4CBCerebellum0.54
0.77
Syt4CTXCerebral cortex1.26
1.5
Syt4HIPHippocampal region0.64
0.8
Syt4HPFHippocampal formation0.88
1
Syt4HYHypothalamus2.24
2.58
Syt4LSXLateral septal complex0.06
0.05
Syt4MBMidbrain1.03
1.18
Syt4MYMedulla2.96
4.97
Syt4OLFOlfactory bulb0.81
0.8
Syt4PPons1.38
2.11
Syt4PALPallidum0.86
1.06
Syt4RHPRetrohippocampal region1.26
1.23
Syt4sAMYStriatum-like amygdalar nuclei1.4
1.71
Syt4STRStriatum0.25
0.3
Syt4STRdStriatum dorsal region0.08
0.09
Syt4STRvStriatum ventral region0.09
0.08
Syt4THThalamus0.92
0.92
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018