AutismKB 2.0

Annotation Detail for TAC3


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Basic Information Top
Gene Symbol:TAC3 ( NKB,NKNB,PRO1155,ZNEUROK1 )
Gene Full Name: tachykinin 3
Band: 12q13.3
Quick LinksEntrez ID:6866; OMIM: 162330; Uniprot ID:TKNK_HUMAN; ENSEMBL ID: ENSG00000166863; HGNC ID: 11521
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal23 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219992_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.45
Adipocyte3.8
AdrenalCortex4.15
Adrenalgland3.1
Amygdala4.65
Appendix3.85
AtrioventricularNode2.6
BDCA4+_DentriticCells3.95
Bonemarrow3.75
BronchialEpithelialCells3.55
CD105+_Endothelial3.65
CD14+_Monocytes3.8
CD19+_BCells(neg._sel.)3.8
CD33+_Myeloid4.55
CD34+4.55
CD4+_Tcells3.9
CD56+_NKCells4.25
CD71+_EarlyErythroid8.15
CD8+_Tcells3.45
CardiacMyocytes4.5
Caudatenucleus5.75
Cerebellum2.95
CerebellumPeduncles4.1
CiliaryGanglion2.45
CingulateCortex5.75
Colorectaladenocarcinoma3.55
DorsalRootGanglion2.65
FetalThyroid3.95
Fetalbrain3.6
Fetalliver3.1
Fetallung3
GlobusPallidus2.7
Heart4.75
Hypothalamus5.7
Kidney4.05
Leukemia_chronicMyelogenousK-5623.25
Leukemia_promyelocytic-HL-603.15
Leukemialymphoblastic(MOLT-4)2.9
Liver6.8
Lung3.95
Lymphnode3.8
Lymphoma_burkitts(Daudi)4.55
Lymphoma_burkitts(Raji)5.05
MedullaOblongata5.6
OccipitalLobe5.2
OlfactoryBulb2.95
Ovary2.65
Pancreas2.9
PancreaticIslet3.9
ParietalLobe5.6
Pituitary4.3
Placenta588.65
Pons10.1
PrefrontalCortex4.8
Prostate4.2
Salivarygland2.9
SkeletalMuscle5.05
Skin2.65
SmoothMuscle4.05
Spinalcord3.9
SubthalamicNucleus3.35
SuperiorCervicalGanglion4.15
TemporalLobe4.3
Testis4
TestisGermCell2.95
TestisIntersitial3.05
TestisLeydigCell3.55
TestisSeminiferousTubule3.4
Thalamus3.7
Thymus2.8
Thyroid4.55
Tongue3.5
Tonsil3.5
Trachea3.15
TrigeminalGanglion3.7
Uterus2.95
UterusCorpus3.2
WholeBlood3.9
Wholebrain5.85
colon4.25
pineal_day4.5
pineal_night4.38
retina4.575
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15122_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.44 ± 0.91
Basal Forebrain6.66 ± 1.54
Basal Part of Pons4.44 ± 0.52
Cerebellar Cortex3.86 ± 0.5
Cerebellar Nuclei4.44 ± 0.64
Claustrum4.47 ± 1.59
Epithalamus5.15 ± 1.13
Frontal Lobe5.25 ± 1.01
Globus Pallidus3.35 ± 2.53
Hypothalamus5.91 ± 1.46
Insula5.48 ± 0.63
Limbic Lobe5.24 ± 1.06
Mesencephalon5.12 ± 1.3
Myelencephalon5.11 ± 1.15
Occipital Lobe4.74 ± 1.29
Parietal Lobe5.45 ± 0.96
Pontine Tegmentum5.29 ± 1.3
Striatum5.91 ± 1.37
Subthalamus4.74 ± 0.92
Temporal Lobe5.78 ± 0.77
Thalamus4.23 ± 0.86
White Matter2.89 ± 1.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tac2CBCerebellum0.68
1.37
Tac2CTXCerebral cortex4.06
4.45
Tac2HIPHippocampal region3.98
8.02
Tac2HPFHippocampal formation3.41
5.7
Tac2HYHypothalamus10.27
13.25
Tac2LSXLateral septal complex1.88
2.01
Tac2MBMidbrain2.03
2.66
Tac2MYMedulla1.46
1.52
Tac2OLFOlfactory bulb6.2
5.14
Tac2PPons1.01
0.8
Tac2PALPallidum7.36
12.11
Tac2RHPRetrohippocampal region2.55
2.89
Tac2sAMYStriatum-like amygdalar nuclei7.51
12.88
Tac2STRStriatum2.54
3.07
Tac2STRdStriatum dorsal region0.89
1.42
Tac2STRvStriatum ventral region4.83
3.28
Tac2THThalamus2.13
3.42
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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