AutismKB 2.0

Annotation Detail for TACC1


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Basic Information Top
Gene Symbol:TACC1 ( DKFZp686K18126,FLJ42304,Ga55,KIAA1103 )
Gene Full Name: transforming, acidic coiled-coil containing protein 1
Band: 8p11.22
Quick LinksEntrez ID:6867; OMIM: 605301; Uniprot ID:TACC1_HUMAN; ENSEMBL ID: ENSG00000147526; HGNC ID: 11522
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus72 / 564012127
neonate4 / 31097128
infant3 / 23620127
juvenile15 / 55556269
adult227 / 1939121117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor3 / 3436687
chondrosarcoma15 / 82823181
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor12 / 26384545
glioma3 / 10688328
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia9 / 9584293
liver tumor13 / 96359134
lung tumor1 / 1031279
lymphoma7 / 7175597
non-neoplasia3 / 9725030
normal456 / 3360307135
ovarian tumor8 / 76682104
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites5 / 40015124
bladder4 / 29757134
blood10 / 12347880
bone8 / 71655111
bone marrow3 / 4880161
brain110 / 110098999
cervix3 / 4817162
connective tissue16 / 149255107
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye22 / 211054104
heart16 / 89626178
intestine29 / 234472123
kidney23 / 211777108
larynx0 / 241450 
liver21 / 207743101
lung40 / 336974118
lymph4 / 4427090
lymph node30 / 91610327
mammary gland14 / 15327191
mouth3 / 6705244
muscle6 / 10771555
nerve4 / 15768253
ovary12 / 102051117
pancreas25 / 214812116
parathyroid6 / 20539292
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta25 / 28082589
prostate22 / 189345116
salivary gland0 / 201550 
skin19 / 21057490
spleen13 / 53952240
stomach7 / 9661972
testis27 / 33044281
thymus6 / 8113173
thyroid4 / 4747384
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord2 / 13680146
uterus33 / 232878141
vascular19 / 51780366
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200911_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1742.6
Adipocyte311
AdrenalCortex223.85
Adrenalgland141.5
Amygdala612.5
Appendix353.45
AtrioventricularNode294.45
BDCA4+_DentriticCells1435.2
Bonemarrow183.75
BronchialEpithelialCells100
CD105+_Endothelial691.5
CD14+_Monocytes614.4
CD19+_BCells(neg._sel.)383.55
CD33+_Myeloid920.6
CD34+588.45
CD4+_Tcells363.45
CD56+_NKCells827.95
CD71+_EarlyErythroid462.6
CD8+_Tcells675.7
CardiacMyocytes54.15
Caudatenucleus424.95
Cerebellum100.65
CerebellumPeduncles174.1
CiliaryGanglion179.1
CingulateCortex563.55
Colorectaladenocarcinoma117.15
DorsalRootGanglion300.85
FetalThyroid303.2
Fetalbrain139.75
Fetalliver138.35
Fetallung577.35
GlobusPallidus226.8
Heart36.5
Hypothalamus775.9
Kidney99.3
Leukemia_chronicMyelogenousK-562190.75
Leukemia_promyelocytic-HL-60190.8
Leukemialymphoblastic(MOLT-4)281.8
Liver29.95
Lung359
Lymphnode449.15
Lymphoma_burkitts(Daudi)332
Lymphoma_burkitts(Raji)23.25
MedullaOblongata416.55
OccipitalLobe548.8
OlfactoryBulb808.15
Ovary225.15
Pancreas111.7
PancreaticIslet325
ParietalLobe412.65
Pituitary271.05
Placenta438.9
Pons242.9
PrefrontalCortex1470.45
Prostate455.8
Salivarygland206.45
SkeletalMuscle10.25
Skin126.45
SmoothMuscle175.8
Spinalcord610.6
SubthalamicNucleus368.1
SuperiorCervicalGanglion174.8
TemporalLobe315.25
Testis185.65
TestisGermCell606.45
TestisIntersitial197.95
TestisLeydigCell157.15
TestisSeminiferousTubule232.7
Thalamus418
Thymus146.95
Thyroid434.5
Tongue224.25
Tonsil286.4
Trachea247.95
TrigeminalGanglion165.75
Uterus1132.45
UterusCorpus374.3
WholeBlood666.25
Wholebrain338.95
colon526.75
pineal_day211.14
pineal_night238.48
retina851.775
small_intestine313
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P60047
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.37 ± 0.11
Basal Forebrain12.12 ± 0.2
Basal Part of Pons12.08 ± 0.2
Cerebellar Cortex11.99 ± 0.17
Cerebellar Nuclei12.32 ± 0.26
Claustrum12.66 ± 0.25
Epithalamus11.97 ± 0.35
Frontal Lobe12.25 ± 0.25
Globus Pallidus12.53 ± 0.19
Hypothalamus11.99 ± 0.19
Insula12.27 ± 0.24
Limbic Lobe12.3 ± 0.3
Mesencephalon12.38 ± 0.23
Myelencephalon12.29 ± 0.28
Occipital Lobe12.59 ± 0.28
Parietal Lobe12.37 ± 0.25
Pontine Tegmentum12.33 ± 0.29
Striatum12.31 ± 0.24
Subthalamus12.34 ± 0.3
Temporal Lobe12.31 ± 0.23
Thalamus12.3 ± 0.24
White Matter12.71 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tacc1CBCerebellum28.07
92.33
Tacc1CTXCerebral cortex100
100
Tacc1HIPHippocampal region87.2
100
Tacc1HPFHippocampal formation96.94
100
Tacc1HYHypothalamus53.9
48.18
Tacc1LSXLateral septal complex87.55
75.22
Tacc1MBMidbrain55.67
57.43
Tacc1MYMedulla57.95
75.86
Tacc1OLFOlfactory bulb100
100
Tacc1PPons47.55
58.93
Tacc1PALPallidum53.66
55.29
Tacc1RHPRetrohippocampal region100
100
Tacc1sAMYStriatum-like amygdalar nuclei77.32
69.75
Tacc1STRStriatum100
100
Tacc1STRdStriatum dorsal region100
100
Tacc1STRvStriatum ventral region100
100
Tacc1THThalamus57.07
54.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499968 22 262 283 ASYHFSPEELDENTSPLLGDAR Peptide Atlas
TACC1_HUMAN_648 11 648 658 TIAQMIEDEQR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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