AutismKB 2.0

Annotation Detail for TADA2A


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Basic Information Top
Gene Symbol:TADA2A ( ADA2,ADA2A,FLJ12705,TADA2L,hADA2 )
Gene Full Name: transcriptional adaptor 2A
Band: 17q12
Quick LinksEntrez ID:6871; OMIM: 602276; Uniprot ID:TAD2A_HUMAN; ENSEMBL ID: ENSG00000108264; HGNC ID: 11531
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia0 / 972500 
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood9 / 12347872
bone1 / 7165513
bone marrow0 / 488010 
brain24 / 110098921
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta4 / 28082514
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210537_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.75
Adipocyte5.3
AdrenalCortex7.9
Adrenalgland4.55
Amygdala5.4
Appendix5.35
AtrioventricularNode4.25
BDCA4+_DentriticCells5.65
Bonemarrow5.3
BronchialEpithelialCells5
CD105+_Endothelial5.4
CD14+_Monocytes5.6
CD19+_BCells(neg._sel.)5.55
CD33+_Myeloid6.9
CD34+6.8
CD4+_Tcells5.85
CD56+_NKCells6.45
CD71+_EarlyErythroid5.05
CD8+_Tcells5.2
CardiacMyocytes6.85
Caudatenucleus4.8
Cerebellum4.3
CerebellumPeduncles6.3
CiliaryGanglion4
CingulateCortex5.55
Colorectaladenocarcinoma5.2
DorsalRootGanglion4.45
FetalThyroid5.5
Fetalbrain5.05
Fetalliver4.65
Fetallung4.2
GlobusPallidus4
Heart6.9
Hypothalamus5.85
Kidney4.55
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.85
Leukemialymphoblastic(MOLT-4)4.55
Liver7
Lung5.75
Lymphnode4.65
Lymphoma_burkitts(Daudi)6.95
Lymphoma_burkitts(Raji)7.4
MedullaOblongata4.9
OccipitalLobe4.85
OlfactoryBulb4.2
Ovary3.75
Pancreas4.4
PancreaticIslet5.75
ParietalLobe6.5
Pituitary6.25
Placenta5.45
Pons5.3
PrefrontalCortex6.25
Prostate6
Salivarygland4.35
SkeletalMuscle6.7
Skin4.25
SmoothMuscle6.1
Spinalcord5.7
SubthalamicNucleus5.05
SuperiorCervicalGanglion6
TemporalLobe5.05
Testis4.5
TestisGermCell4.5
TestisIntersitial4.5
TestisLeydigCell5.35
TestisSeminiferousTubule4.8
Thalamus5.5
Thymus4.25
Thyroid6.3
Tongue5.7
Tonsil5.2
Trachea4.45
TrigeminalGanglion5.3
Uterus4.2
UterusCorpus4.8
WholeBlood5.8
Wholebrain4.2
colon5.35
pineal_day6.38
pineal_night6.22
retina6.375
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5826_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.47 ± 0.21
Basal Forebrain9.51 ± 0.16
Basal Part of Pons9.49 ± 0.23
Cerebellar Cortex9.64 ± 0.19
Cerebellar Nuclei9.23 ± 0.26
Claustrum9.36 ± 0.35
Epithalamus9.53 ± 0.3
Frontal Lobe9.41 ± 0.28
Globus Pallidus9.44 ± 0.15
Hypothalamus9.57 ± 0.24
Insula9.45 ± 0.21
Limbic Lobe9.25 ± 0.26
Mesencephalon9.51 ± 0.23
Myelencephalon9.41 ± 0.27
Occipital Lobe9.54 ± 0.24
Parietal Lobe9.58 ± 0.21
Pontine Tegmentum9.47 ± 0.28
Striatum9.23 ± 0.22
Subthalamus9.57 ± 0.14
Temporal Lobe9.48 ± 0.23
Thalamus9.55 ± 0.24
White Matter9.76 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tada2lCBCerebellum0.77
1.22
Tada2lCTXCerebral cortex0.64
0.6
Tada2lHIPHippocampal region1.7
1.67
Tada2lHPFHippocampal formation1.41
1.3
Tada2lHYHypothalamus0.23
0.23
Tada2lLSXLateral septal complex0.25
0.47
Tada2lMBMidbrain0.18
0.31
Tada2lMYMedulla0.67
0.9
Tada2lOLFOlfactory bulb2.13
3.38
Tada2lPPons0.81
1.26
Tada2lPALPallidum0.16
0.26
Tada2lRHPRetrohippocampal region0.58
0.46
Tada2lsAMYStriatum-like amygdalar nuclei0.84
0.6
Tada2lSTRStriatum0.16
0.18
Tada2lSTRdStriatum dorsal region0.01
0.04
Tada2lSTRvStriatum ventral region0.28
0.33
Tada2lTHThalamus0.43
0.37
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018