AutismKB 2.0

Annotation Detail for TAF4


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Basic Information Top
Gene Symbol:TAF4 ( FLJ41943,TAF2C,TAF2C1,TAF4A,TAFII130,TAFII135 )
Gene Full Name: TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
Band: 20q13.33
Quick LinksEntrez ID:6874; OMIM: 601796; Uniprot ID:TAF4_HUMAN; ENSEMBL ID: ENSG00000130699; HGNC ID: 11537
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal67 / 336030719
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye5 / 21105423
heart2 / 8962622
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland9 / 15327158
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach2 / 9661920
testis11 / 33044233
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213090_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.55
Adipocyte6.05
AdrenalCortex7.45
Adrenalgland6
Amygdala7.6
Appendix7.25
AtrioventricularNode5.65
BDCA4+_DentriticCells9.5
Bonemarrow6.9
BronchialEpithelialCells5.8
CD105+_Endothelial30.45
CD14+_Monocytes19.1
CD19+_BCells(neg._sel.)8.7
CD33+_Myeloid21.4
CD34+22
CD4+_Tcells11.9
CD56+_NKCells54.3
CD71+_EarlyErythroid24.9
CD8+_Tcells16.35
CardiacMyocytes9.6
Caudatenucleus6.45
Cerebellum5.75
CerebellumPeduncles7.65
CiliaryGanglion5.1
CingulateCortex6.45
Colorectaladenocarcinoma14.95
DorsalRootGanglion6.2
FetalThyroid6.65
Fetalbrain17.5
Fetalliver8.8
Fetallung5.8
GlobusPallidus5.1
Heart8.75
Hypothalamus6.95
Kidney5.65
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-606.15
Leukemialymphoblastic(MOLT-4)52.75
Liver9.1
Lung12.2
Lymphnode6.3
Lymphoma_burkitts(Daudi)8.45
Lymphoma_burkitts(Raji)10.1
MedullaOblongata5.6
OccipitalLobe5.6
OlfactoryBulb5.85
Ovary4.7
Pancreas5.3
PancreaticIslet7.15
ParietalLobe6.8
Pituitary6.9
Placenta9.3
Pons6.55
PrefrontalCortex8.1
Prostate10.05
Salivarygland5.45
SkeletalMuscle8.35
Skin5.9
SmoothMuscle7.35
Spinalcord7.55
SubthalamicNucleus5.75
SuperiorCervicalGanglion8.35
TemporalLobe6
Testis10.4
TestisGermCell6.2
TestisIntersitial6.25
TestisLeydigCell7.8
TestisSeminiferousTubule7.65
Thalamus6.55
Thymus7.65
Thyroid9
Tongue6.75
Tonsil6.6
Trachea5.5
TrigeminalGanglion6.95
Uterus7.1
UterusCorpus6.35
WholeBlood13.05
Wholebrain7.65
colon7.15
pineal_day8.12
pineal_night8.52
retina8.5
small_intestine8.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10422_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.58 ± 0.43
Basal Forebrain6.36 ± 0.17
Basal Part of Pons5.91 ± 0.37
Cerebellar Cortex6.3 ± 0.37
Cerebellar Nuclei6.11 ± 0.37
Claustrum6.75 ± 0.66
Epithalamus5.93 ± 0.25
Frontal Lobe5.87 ± 0.45
Globus Pallidus6.66 ± 0.35
Hypothalamus5.79 ± 0.37
Insula5.98 ± 0.46
Limbic Lobe6.46 ± 0.51
Mesencephalon6.26 ± 0.48
Myelencephalon6.22 ± 0.53
Occipital Lobe6.68 ± 0.59
Parietal Lobe6.21 ± 0.51
Pontine Tegmentum6.11 ± 0.49
Striatum6.56 ± 0.62
Subthalamus5.68 ± 0.23
Temporal Lobe6.11 ± 0.44
Thalamus6.1 ± 0.43
White Matter7.21 ± 0.49
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010648 30 1019 1048 KVDCPGPGSGAEGSGPGSVVPGSSGVGTPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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