AutismKB 2.0

Annotation Detail for TAF5


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Basic Information Top
Gene Symbol:TAF5 ( TAF2D,TAFII100 )
Gene Full Name: TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
Band: 10q24.33
Quick LinksEntrez ID:6877; OMIM: 601787; Uniprot ID:TAF5_HUMAN; ENSEMBL ID: ENSG00000148835; HGNC ID: 11539
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus6 / 56401210
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal23 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210053_at
Cell line Expression level Expression bar
721_B_lymphoblasts54.25
Adipocyte6.55
AdrenalCortex7.05
Adrenalgland5.55
Amygdala6.8
Appendix7.25
AtrioventricularNode6.05
BDCA4+_DentriticCells12.4
Bonemarrow6.7
BronchialEpithelialCells6.05
CD105+_Endothelial98.4
CD14+_Monocytes15.8
CD19+_BCells(neg._sel.)8.35
CD33+_Myeloid16
CD34+69.55
CD4+_Tcells17
CD56+_NKCells51.9
CD71+_EarlyErythroid44.45
CD8+_Tcells14.25
CardiacMyocytes10.2
Caudatenucleus5.95
Cerebellum5.4
CerebellumPeduncles9.55
CiliaryGanglion5.1
CingulateCortex6.75
Colorectaladenocarcinoma6.15
DorsalRootGanglion5.3
FetalThyroid7.15
Fetalbrain7.1
Fetalliver5.85
Fetallung5.55
GlobusPallidus4.8
Heart8.8
Hypothalamus7.4
Kidney5.35
Leukemia_chronicMyelogenousK-5628.65
Leukemia_promyelocytic-HL-6014.15
Leukemialymphoblastic(MOLT-4)25.95
Liver8.6
Lung6.5
Lymphnode6
Lymphoma_burkitts(Daudi)23.95
Lymphoma_burkitts(Raji)9.25
MedullaOblongata6
OccipitalLobe5.8
OlfactoryBulb5.25
Ovary4.45
Pancreas4.9
PancreaticIslet7.15
ParietalLobe7
Pituitary7.8
Placenta6.75
Pons6.4
PrefrontalCortex8.45
Prostate7.7
Salivarygland5.5
SkeletalMuscle8.75
Skin5.35
SmoothMuscle6.65
Spinalcord7.1
SubthalamicNucleus5.75
SuperiorCervicalGanglion11.5
TemporalLobe6.05
Testis5.9
TestisGermCell38.9
TestisIntersitial14.15
TestisLeydigCell10.4
TestisSeminiferousTubule25.25
Thalamus6.7
Thymus5.4
Thyroid7.95
Tongue6.55
Tonsil6.5
Trachea5.6
TrigeminalGanglion6.65
Uterus5.25
UterusCorpus6.05
WholeBlood9.45
Wholebrain5.2
colon6.75
pineal_day8.22
pineal_night7.82
retina7.875
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10571_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.21 ± 0.99
Basal Forebrain2.47 ± 0.28
Basal Part of Pons2.54 ± 0.37
Cerebellar Cortex3.43 ± 0.37
Cerebellar Nuclei3.14 ± 0.74
Claustrum3.26 ± 0.55
Epithalamus2.66 ± 0.75
Frontal Lobe2.91 ± 0.63
Globus Pallidus2.35 ± 0.68
Hypothalamus2.94 ± 0.72
Insula2.61 ± 0.65
Limbic Lobe2.78 ± 0.64
Mesencephalon2.97 ± 0.72
Myelencephalon2.85 ± 0.6
Occipital Lobe2.82 ± 0.63
Parietal Lobe2.9 ± 0.65
Pontine Tegmentum2.99 ± 0.66
Striatum2.39 ± 0.64
Subthalamus3.07 ± 0.64
Temporal Lobe2.91 ± 0.59
Thalamus2.77 ± 0.62
White Matter2.66 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Taf5CBCerebellum3.32
3.69
Taf5CTXCerebral cortex1.94
1.55
Taf5HIPHippocampal region1.5
1.35
Taf5HPFHippocampal formation1.39
1.17
Taf5HYHypothalamus0.51
0.54
Taf5LSXLateral septal complex0.22
0.24
Taf5MBMidbrain2.17
2.38
Taf5MYMedulla7.49
7.97
Taf5OLFOlfactory bulb1.21
1.3
Taf5PPons3.82
4.33
Taf5PALPallidum0.86
0.85
Taf5RHPRetrohippocampal region1.23
0.92
Taf5sAMYStriatum-like amygdalar nuclei0.35
0.43
Taf5STRStriatum0.56
0.53
Taf5STRdStriatum dorsal region0.63
0.59
Taf5STRvStriatum ventral region0.55
0.47
Taf5THThalamus1.76
1.59
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010436 13 622 634 IFAGHLADVNCTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018