AutismKB 2.0

Annotation Detail for TARS


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TARS ( MGC9344,ThrRS )
Gene Full Name: threonyl-tRNA synthetase
Band: 5p13.3
Quick LinksEntrez ID:6897; OMIM: 187790; Uniprot ID:SYTC_HUMAN; ENSEMBL ID: ENSG00000113407; HGNC ID: 11572
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst12 / 62319192
fetus75 / 564012132
neonate8 / 31097257
infant2 / 2362084
juvenile7 / 55556125
adult255 / 1939121131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma4 / 17475228
breast (mammary gland) tumor18 / 94178191
cervical tumor16 / 34366465
chondrosarcoma20 / 82823241
colorectal tumor13 / 114246113
esophageal tumor4 / 17290231
gastrointestinal tumor28 / 119369234
germ cell tumor59 / 263845223
glioma13 / 106883121
head and neck tumor60 / 136302440
kidney tumor17 / 68959246
leukemia8 / 9584283
liver tumor14 / 96359145
lung tumor14 / 103127135
lymphoma22 / 71755306
non-neoplasia5 / 9725051
normal358 / 3360307106
ovarian tumor2 / 7668226
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer16 / 102680155
retinoblastoma8 / 46356172
skin tumor11 / 12494988
soft tissue/muscle tissue tumor22 / 125191175
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland4 / 33197120
ascites15 / 40015374
bladder8 / 29757268
blood21 / 123478170
bone14 / 71655195
bone marrow9 / 48801184
brain111 / 1100989100
cervix16 / 48171332
connective tissue26 / 149255174
ear1 / 1621261
embryonic tissue34 / 215722157
esophagus4 / 20209197
eye18 / 21105485
heart7 / 8962678
intestine26 / 234472110
kidney47 / 211777221
larynx4 / 24145165
liver36 / 207743173
lung34 / 336974100
lymph20 / 44270451
lymph node2 / 9161021
mammary gland21 / 153271137
mouth31 / 67052462
muscle19 / 107715176
nerve0 / 157680 
ovary6 / 10205158
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta47 / 280825167
prostate23 / 189345121
salivary gland2 / 2015599
skin32 / 210574151
spleen4 / 5395274
stomach8 / 9661982
testis32 / 33044296
thymus8 / 8113198
thyroid27 / 47473568
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus23 / 23287898
vascular11 / 51780212
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201263_at
Cell line Expression level Expression bar
721_B_lymphoblasts895.15
Adipocyte67.35
AdrenalCortex40.2
Adrenalgland14.25
Amygdala25.15
Appendix20.3
AtrioventricularNode22.35
BDCA4+_DentriticCells81.75
Bonemarrow21.5
BronchialEpithelialCells265.85
CD105+_Endothelial220
CD14+_Monocytes82
CD19+_BCells(neg._sel.)78.1
CD33+_Myeloid95.85
CD34+211
CD4+_Tcells44.65
CD56+_NKCells108.15
CD71+_EarlyErythroid101.85
CD8+_Tcells42.25
CardiacMyocytes254.8
Caudatenucleus25.2
Cerebellum14.6
CerebellumPeduncles30.45
CiliaryGanglion20.8
CingulateCortex29.65
Colorectaladenocarcinoma84.1
DorsalRootGanglion18.9
FetalThyroid29.2
Fetalbrain40.4
Fetalliver31.15
Fetallung37.3
GlobusPallidus19.8
Heart15.5
Hypothalamus40.85
Kidney16.4
Leukemia_chronicMyelogenousK-562569.35
Leukemia_promyelocytic-HL-60114.6
Leukemialymphoblastic(MOLT-4)135.95
Liver16.7
Lung15.55
Lymphnode23.2
Lymphoma_burkitts(Daudi)198.15
Lymphoma_burkitts(Raji)97.7
MedullaOblongata19.2
OccipitalLobe23.9
OlfactoryBulb23.45
Ovary18.3
Pancreas79.1
PancreaticIslet62.55
ParietalLobe28.15
Pituitary43.75
Placenta21
Pons23.85
PrefrontalCortex25.85
Prostate29.6
Salivarygland29.25
SkeletalMuscle31.3
Skin21.35
SmoothMuscle389.4
Spinalcord29.95
SubthalamicNucleus24.95
SuperiorCervicalGanglion17.45
TemporalLobe25.6
Testis18.5
TestisGermCell22.65
TestisIntersitial16.1
TestisLeydigCell26.15
TestisSeminiferousTubule20.5
Thalamus31.9
Thymus15.05
Thyroid35.3
Tongue40.75
Tonsil36.3
Trachea19.55
TrigeminalGanglion29
Uterus18.45
UterusCorpus23.85
WholeBlood24.8
Wholebrain11.8
colon65.75
pineal_day67.26
pineal_night63.72
retina29.925
small_intestine30.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7698_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.06 ± 0.24
Basal Forebrain6.87 ± 0.29
Basal Part of Pons7.29 ± 0.16
Cerebellar Cortex7.19 ± 0.2
Cerebellar Nuclei7.26 ± 0.19
Claustrum6.77 ± 0.47
Epithalamus7.08 ± 0.21
Frontal Lobe7.01 ± 0.31
Globus Pallidus7.21 ± 0.22
Hypothalamus7.2 ± 0.25
Insula6.97 ± 0.2
Limbic Lobe6.96 ± 0.31
Mesencephalon7.01 ± 0.37
Myelencephalon7.02 ± 0.28
Occipital Lobe7.09 ± 0.21
Parietal Lobe7.02 ± 0.28
Pontine Tegmentum7 ± 0.27
Striatum7.02 ± 0.3
Subthalamus7.46 ± 0.15
Temporal Lobe6.97 ± 0.25
Thalamus7.13 ± 0.27
White Matter7.8 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TarsCBCerebellum9.39
11.52
TarsCTXCerebral cortex12.93
9.9
TarsHIPHippocampal region24.53
24.92
TarsHPFHippocampal formation22.73
21.43
TarsHYHypothalamus13.82
10.55
TarsLSXLateral septal complex4.58
3.83
TarsMBMidbrain8.96
8.54
TarsMYMedulla10.19
14.62
TarsOLFOlfactory bulb26.67
23.42
TarsPPons15.08
18.86
TarsPALPallidum8.12
7.41
TarsRHPRetrohippocampal region19.48
16.23
TarssAMYStriatum-like amygdalar nuclei13.04
9.39
TarsSTRStriatum5.23
3.77
TarsSTRdStriatum dorsal region3.73
2.54
TarsSTRvStriatum ventral region6.78
5.05
TarsTHThalamus24.03
19.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001772 20 329 348 DQELYFFHELSPGSCFFLPK Peptide Atlas
SYTC_HUMAN_1 44 1 44 MFEEKASSPSGKMGGEEKPIGAGEEKQKEGGKKKNKEGSGDGGR PRIDE
SYTC_HUMAN_223 9 223 231 KETLLAMFK PRIDE
SYTC_HUMAN_254 9 254 262 CGPLIDLCR PRIDE
SYTC_HUMAN_296 10 296 305 IYGISFPDPK PRIDE
SYTC_HUMAN_328 20 328 347 DQELYFFHELSPGSCFFLPK PRIDE
SYTC_HUMAN_348 13 348 360 GAYIYNALIEFIR PRIDE
SYTC_HUMAN_442 12 442 453 NELSGALTGLTR PRIDE
SYTC_HUMAN_58 8 58 65 LEMYNILK PRIDE
SYTC_HUMAN_599 20 599 618 MIAILTENYGGKWPFWLSPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved