AutismKB 2.0

Annotation Detail for TBXAS1


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Basic Information Top
Gene Symbol:TBXAS1 ( CYP5,CYP5A1,FLJ52771,GHOSAL,THAS,TS,TXAS,TXS )
Gene Full Name: thromboxane A synthase 1 (platelet)
Band: 7q34
Quick LinksEntrez ID:6916; OMIM: 274180; Uniprot ID:THAS_HUMAN; ENSEMBL ID: ENSG00000059377; HGNC ID: 11609
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate4 / 31097128
infant0 / 236200 
juvenile1 / 5555617
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma7 / 10688365
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal138 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood16 / 123478129
bone2 / 7165527
bone marrow4 / 4880181
brain27 / 110098924
cervix2 / 4817141
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine16 / 23447268
kidney12 / 21177756
larynx0 / 241450 
liver7 / 20774333
lung14 / 33697441
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas11 / 21481251
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin0 / 2105740 
spleen15 / 53952278
stomach1 / 9661910
testis2 / 3304426
thymus7 / 8113186
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208130_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.8
Adipocyte4.4
AdrenalCortex4.65
Adrenalgland3.8
Amygdala4.8
Appendix4.5
AtrioventricularNode3.35
BDCA4+_DentriticCells31.75
Bonemarrow5.75
BronchialEpithelialCells4.45
CD105+_Endothelial4.6
CD14+_Monocytes231.35
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid132.6
CD34+15.25
CD4+_Tcells5
CD56+_NKCells26.4
CD71+_EarlyErythroid4.15
CD8+_Tcells4.4
CardiacMyocytes5.5
Caudatenucleus4.05
Cerebellum3.65
CerebellumPeduncles5.05
CiliaryGanglion3.2
CingulateCortex4.5
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.85
FetalThyroid4.3
Fetalbrain4.4
Fetalliver3.85
Fetallung3.8
GlobusPallidus3.25
Heart6.65
Hypothalamus5.3
Kidney3.6
Leukemia_chronicMyelogenousK-5624.05
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.45
Liver5.9
Lung25.75
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.7
Lymphoma_burkitts(Raji)6.3
MedullaOblongata4.1
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary2.95
Pancreas3.55
PancreaticIslet4.8
ParietalLobe4.7
Pituitary5.25
Placenta4.55
Pons4.3
PrefrontalCortex5.5
Prostate5.45
Salivarygland3.6
SkeletalMuscle5.2
Skin3.35
SmoothMuscle5.1
Spinalcord4.85
SubthalamicNucleus4.05
SuperiorCervicalGanglion5
TemporalLobe4.05
Testis3.7
TestisGermCell3.45
TestisIntersitial3.65
TestisLeydigCell4.3
TestisSeminiferousTubule3.8
Thalamus4.55
Thymus5.95
Thyroid5.55
Tongue4.4
Tonsil4.35
Trachea3.8
TrigeminalGanglion4.3
Uterus3.75
UterusCorpus4
WholeBlood72.95
Wholebrain3.75
colon4.65
pineal_day5.5
pineal_night5.54
retina5.725
small_intestine5.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16570_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.99 ± 0.97
Basal Forebrain1.56 ± 0.17
Basal Part of Pons1.26 ± 0.3
Cerebellar Cortex1.35 ± 0.53
Cerebellar Nuclei1.88 ± 0.77
Claustrum2.37 ± 0.8
Epithalamus1.54 ± 0.62
Frontal Lobe1.42 ± 0.63
Globus Pallidus2.37 ± 0.69
Hypothalamus1.74 ± 0.74
Insula1.43 ± 0.51
Limbic Lobe1.54 ± 0.59
Mesencephalon1.72 ± 0.69
Myelencephalon1.61 ± 0.64
Occipital Lobe1.73 ± 0.84
Parietal Lobe1.56 ± 0.64
Pontine Tegmentum1.56 ± 0.62
Striatum1.79 ± 0.61
Subthalamus1.73 ± 0.59
Temporal Lobe1.45 ± 0.59
Thalamus1.54 ± 0.6
White Matter1.97 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tbxas1CBCerebellum3.49
3.8
Tbxas1CTXCerebral cortex1.46
1.12
Tbxas1HIPHippocampal region3.24
2.65
Tbxas1HPFHippocampal formation3.46
2.62
Tbxas1HYHypothalamus0.65
0.49
Tbxas1LSXLateral septal complex0.23
0.15
Tbxas1MBMidbrain0.79
0.81
Tbxas1MYMedulla5.61
5.57
Tbxas1OLFOlfactory bulb6.31
3.99
Tbxas1PPons4.49
4.2
Tbxas1PALPallidum1.56
1.27
Tbxas1RHPRetrohippocampal region4.1
2.79
Tbxas1sAMYStriatum-like amygdalar nuclei3.27
2.14
Tbxas1STRStriatum1.48
1.06
Tbxas1STRdStriatum dorsal region0.66
0.65
Tbxas1STRvStriatum ventral region3.95
2.21
Tbxas1THThalamus1.09
0.74
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00487532 12 170 181 YAESGDAFDIQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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