AutismKB 2.0

Annotation Detail for TCEB2


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Basic Information Top
Gene Symbol:TCEB2 ( ELOB,SIII )
Gene Full Name: transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
Band: 16p12.3
Quick LinksEntrez ID:6923; OMIM: 600787; Uniprot ID:ELOB_HUMAN; ENSEMBL ID: ENSG00000103363; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus46 / 56401281
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult154 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma13 / 106883121
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia11 / 95842114
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal319 / 336030794
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer9 / 10268087
retinoblastoma4 / 4635686
skin tumor5 / 12494940
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood16 / 123478129
bone4 / 7165555
bone marrow8 / 48801163
brain47 / 110098942
cervix0 / 481710 
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye21 / 21105499
heart14 / 89626156
intestine14 / 23447259
kidney12 / 21177756
larynx2 / 2414582
liver29 / 207743139
lung19 / 33697456
lymph1 / 4427022
lymph node2 / 9161021
mammary gland8 / 15327152
mouth2 / 6705229
muscle46 / 107715427
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid9 / 20539438
pharynx1 / 4132824
pituitary gland3 / 16585180
placenta9 / 28082532
prostate20 / 189345105
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach1 / 9661910
testis18 / 33044254
thymus0 / 811310 
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord2 / 13680146
uterus7 / 23287830
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213877_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts55.35
Adipocyte67.1
AdrenalCortex73.25
Adrenalgland50.85
Amygdala73.45
Appendix72.05
AtrioventricularNode60
BDCA4+_DentriticCells54.85
Bonemarrow71.35
BronchialEpithelialCells66.55
CD105+_Endothelial77.9
CD14+_Monocytes72.65
CD19+_BCells(neg._sel.)60.1
CD33+_Myeloid68.7
CD34+66.7
CD4+_Tcells63.5
CD56+_NKCells70.55
CD71+_EarlyErythroid98.4
CD8+_Tcells51.15
CardiacMyocytes94.5
Caudatenucleus61.6
Cerebellum66.5
CerebellumPeduncles96.15
CiliaryGanglion49.05
CingulateCortex72.4
Colorectaladenocarcinoma86.2
DorsalRootGanglion62.95
FetalThyroid69.05
Fetalbrain169.7
Fetalliver67.05
Fetallung59.75
GlobusPallidus49.7
Heart99.9
Hypothalamus59.7
Kidney56.3
Leukemia_chronicMyelogenousK-56274.05
Leukemia_promyelocytic-HL-6074.25
Leukemialymphoblastic(MOLT-4)68.25
Liver101.8
Lung78.15
Lymphnode57.5
Lymphoma_burkitts(Daudi)90.45
Lymphoma_burkitts(Raji)117.9
MedullaOblongata55.05
OccipitalLobe59.85
OlfactoryBulb51.6
Ovary51.8
Pancreas57.4
PancreaticIslet73
ParietalLobe74.6
Pituitary90.25
Placenta54.45
Pons65
PrefrontalCortex80.65
Prostate75.75
Salivarygland51.15
SkeletalMuscle84.25
Skin54.6
SmoothMuscle79.05
Spinalcord70.75
SubthalamicNucleus60.7
SuperiorCervicalGanglion82.95
TemporalLobe62.05
Testis67.9
TestisGermCell66.55
TestisIntersitial88.05
TestisLeydigCell69.4
TestisSeminiferousTubule71.6
Thalamus61.55
Thymus54.25
Thyroid87.6
Tongue68.55
Tonsil72.45
Trachea53.6
TrigeminalGanglion70.75
Uterus71.45
UterusCorpus69.8
WholeBlood74.4
Wholebrain61.15
colon67.75
pineal_day84.04
pineal_night81.86
retina77
small_intestine58.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P312181
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.67 ± 0.17
Basal Forebrain13.55 ± 0.17
Basal Part of Pons13.69 ± 0.18
Cerebellar Cortex13.36 ± 0.18
Cerebellar Nuclei13.81 ± 0.18
Claustrum13.6 ± 0.14
Epithalamus13.42 ± 0.15
Frontal Lobe13.62 ± 0.24
Globus Pallidus13.84 ± 0.23
Hypothalamus13.81 ± 0.22
Insula13.62 ± 0.3
Limbic Lobe13.51 ± 0.34
Mesencephalon13.55 ± 0.27
Myelencephalon13.55 ± 0.26
Occipital Lobe13.24 ± 0.24
Parietal Lobe13.54 ± 0.25
Pontine Tegmentum13.6 ± 0.27
Striatum13.74 ± 0.19
Subthalamus13.73 ± 0.1
Temporal Lobe13.63 ± 0.3
Thalamus13.54 ± 0.2
White Matter13.72 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tceb2CBCerebellum28.68
75.08
Tceb2CTXCerebral cortex100
100
Tceb2HIPHippocampal region75.3
100
Tceb2HPFHippocampal formation83.77
100
Tceb2HYHypothalamus84.09
85.33
Tceb2LSXLateral septal complex100
100
Tceb2MBMidbrain71.16
82.79
Tceb2MYMedulla69.25
100
Tceb2OLFOlfactory bulb99.05
100
Tceb2PPons64.97
92.42
Tceb2PALPallidum77.3
91.66
Tceb2RHPRetrohippocampal region99.58
100
Tceb2sAMYStriatum-like amygdalar nuclei87.55
85.19
Tceb2STRStriatum83.27
75.94
Tceb2STRdStriatum dorsal region80.53
71.69
Tceb2STRvStriatum ventral region77.64
69.97
Tceb2THThalamus95.04
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ELOB_HUMAN_0 0 0 0 LYKDDQLLDDGK PRIDE
ELOB_HUMAN_1 8 1 8 MDVFLMIR PRIDE
ELOB_HUMAN_19 10 19 28 ESSTVFELKR PRIDE
ELOB_HUMAN_43 12 43 54 LYKDDQLLDDGK PRIDE
ELOB_HUMAN_69 12 69 80 PQAPATVGLAFR PRIDE
PAp00007826 25 56 80 TLGECGFTSQTARPQAPATVGLAFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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