AutismKB 2.0

Annotation Detail for TCF7


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Basic Information Top
Gene Symbol:TCF7 ( FLJ36364,MGC47735,TCF-1 )
Gene Full Name: transcription factor 7 (T-cell specific, HMG-box)
Band: 5q31.1
Quick LinksEntrez ID:6932; OMIM: 189908; Uniprot ID:TCF7_HUMAN; ENSEMBL ID: ENSG00000081059; HGNC ID: 11639
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile10 / 55556179
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia19 / 95842198
liver tumor13 / 96359134
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal60 / 336030717
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood13 / 123478105
bone4 / 7165555
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine7 / 23447229
kidney3 / 21177714
larynx0 / 241450 
liver16 / 20774377
lung0 / 3369740 
lymph0 / 442700 
lymph node14 / 91610152
mammary gland8 / 15327152
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland3 / 20155148
skin1 / 2105744
spleen6 / 53952111
stomach1 / 9661910
testis2 / 3304426
thymus125 / 811311540
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205255_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts255.65
Adipocyte189.85
AdrenalCortex343.55
Adrenalgland147.55
Amygdala293.6
Appendix389.45
AtrioventricularNode335.15
BDCA4+_DentriticCells509.95
Bonemarrow205.35
BronchialEpithelialCells111.6
CD105+_Endothelial211
CD14+_Monocytes215.5
CD19+_BCells(neg._sel.)348
CD33+_Myeloid285.4
CD34+264.35
CD4+_Tcells2781.85
CD56+_NKCells850.15
CD71+_EarlyErythroid155.75
CD8+_Tcells2609.55
CardiacMyocytes258.8
Caudatenucleus189.55
Cerebellum166.2
CerebellumPeduncles289.75
CiliaryGanglion182.7
CingulateCortex276.45
Colorectaladenocarcinoma385.4
DorsalRootGanglion214.55
FetalThyroid224.05
Fetalbrain371.9
Fetalliver165.2
Fetallung184.5
GlobusPallidus222.4
Heart195.6
Hypothalamus258.9
Kidney165.75
Leukemia_chronicMyelogenousK-562177.3
Leukemia_promyelocytic-HL-60140.3
Leukemialymphoblastic(MOLT-4)1264.5
Liver256.7
Lung272.6
Lymphnode489.15
Lymphoma_burkitts(Daudi)263.3
Lymphoma_burkitts(Raji)311.95
MedullaOblongata230.9
OccipitalLobe295.3
OlfactoryBulb200.7
Ovary129.25
Pancreas217.45
PancreaticIslet250.5
ParietalLobe355.95
Pituitary274.9
Placenta196.35
Pons401
PrefrontalCortex284.1
Prostate1792.6
Salivarygland161.5
SkeletalMuscle232.45
Skin330.15
SmoothMuscle170.6
Spinalcord218.4
SubthalamicNucleus259.15
SuperiorCervicalGanglion600.45
TemporalLobe199.2
Testis200.35
TestisGermCell209.05
TestisIntersitial226.9
TestisLeydigCell274.5
TestisSeminiferousTubule284.95
Thalamus210.6
Thymus2136.55
Thyroid462.2
Tongue319.45
Tonsil476.35
Trachea172.7
TrigeminalGanglion379.65
Uterus180.55
UterusCorpus184.1
WholeBlood169.9
Wholebrain144.65
colon279.15
pineal_day306.9
pineal_night326.26
retina310.85
small_intestine318.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1208_PI416379584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.45 ± 1.16
Basal Forebrain2.04 ± 0.49
Basal Part of Pons1.64 ± 0.32
Cerebellar Cortex1.89 ± 0.87
Cerebellar Nuclei2.27 ± 0.8
Claustrum2.75 ± 0.8
Epithalamus2.26 ± 0.76
Frontal Lobe1.81 ± 0.61
Globus Pallidus2.63 ± 0.57
Hypothalamus1.92 ± 0.66
Insula1.82 ± 0.54
Limbic Lobe2.06 ± 0.66
Mesencephalon2.18 ± 0.76
Myelencephalon2.04 ± 0.8
Occipital Lobe2.02 ± 0.59
Parietal Lobe2.12 ± 1.08
Pontine Tegmentum2.05 ± 0.72
Striatum2.11 ± 0.56
Subthalamus2.1 ± 0.7
Temporal Lobe1.91 ± 0.78
Thalamus1.88 ± 0.61
White Matter3.38 ± 1.01
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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