AutismKB 2.0

Annotation Detail for C2orf3


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Basic Information Top
Gene Symbol:C2orf3 ( DNABF,GCF,TCF9 )
Gene Full Name: chromosome 2 open reading frame 3
Band: 2p11.2-p11.1
Quick LinksEntrez ID:6936; OMIM: 189901; Uniprot ID:GCF_HUMAN; ENSEMBL ID: ENSG00000005436; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal96 / 336030728
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow2 / 4880140
brain21 / 110098919
cervix2 / 4817141
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine8 / 23447234
kidney9 / 21177742
larynx0 / 241450 
liver7 / 20774333
lung4 / 33697411
lymph0 / 442700 
lymph node8 / 9161087
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve2 / 15768126
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate5 / 18934526
salivary gland1 / 2015549
skin7 / 21057433
spleen2 / 5395237
stomach0 / 966190 
testis12 / 33044236
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216305_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts40.25
Adipocyte6.4
AdrenalCortex10.35
Adrenalgland5.85
Amygdala5.95
Appendix7.7
AtrioventricularNode5.1
BDCA4+_DentriticCells24.7
Bonemarrow6.25
BronchialEpithelialCells6
CD105+_Endothelial18.25
CD14+_Monocytes8.4
CD19+_BCells(neg._sel.)8.3
CD33+_Myeloid8.45
CD34+8.75
CD4+_Tcells7.1
CD56+_NKCells11.85
CD71+_EarlyErythroid6.05
CD8+_Tcells14.15
CardiacMyocytes9.1
Caudatenucleus5.3
Cerebellum5.1
CerebellumPeduncles7.35
CiliaryGanglion5.35
CingulateCortex6.55
Colorectaladenocarcinoma6.25
DorsalRootGanglion6.85
FetalThyroid6.7
Fetalbrain6.1
Fetalliver9.65
Fetallung6
GlobusPallidus6.2
Heart8.2
Hypothalamus6.65
Kidney5.7
Leukemia_chronicMyelogenousK-5625.9
Leukemia_promyelocytic-HL-6013.1
Leukemialymphoblastic(MOLT-4)12.15
Liver8.45
Lung6.2
Lymphnode6.05
Lymphoma_burkitts(Daudi)8.3
Lymphoma_burkitts(Raji)8.55
MedullaOblongata9.95
OccipitalLobe5.8
OlfactoryBulb5.05
Ovary4.55
Pancreas5.95
PancreaticIslet9.5
ParietalLobe6.7
Pituitary7.4
Placenta5.6
Pons6.15
PrefrontalCortex8.1
Prostate6.75
Salivarygland5.25
SkeletalMuscle9.55
Skin5.05
SmoothMuscle7.3
Spinalcord6.15
SubthalamicNucleus5.95
SuperiorCervicalGanglion11.2
TemporalLobe5.7
Testis5.05
TestisGermCell7.55
TestisIntersitial6.4
TestisLeydigCell6.35
TestisSeminiferousTubule5.25
Thalamus6.25
Thymus4.35
Thyroid7.7
Tongue6.25
Tonsil6.1
Trachea5.15
TrigeminalGanglion6.4
Uterus11.2
UterusCorpus5.85
WholeBlood6.95
Wholebrain4.55
colon6.3
pineal_day9.34
pineal_night7.28
retina7.375
small_intestine5.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8935_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.72 ± 0.33
Basal Forebrain5.79 ± 0.34
Basal Part of Pons5.23 ± 0.36
Cerebellar Cortex5.62 ± 0.33
Cerebellar Nuclei5.65 ± 0.48
Claustrum5.22 ± 0.48
Epithalamus6.08 ± 0.34
Frontal Lobe5.4 ± 0.38
Globus Pallidus6.04 ± 0.33
Hypothalamus5.63 ± 0.27
Insula5.42 ± 0.29
Limbic Lobe5.6 ± 0.45
Mesencephalon5.7 ± 0.31
Myelencephalon5.54 ± 0.44
Occipital Lobe5.9 ± 0.34
Parietal Lobe5.58 ± 0.33
Pontine Tegmentum5.6 ± 0.39
Striatum5.7 ± 0.36
Subthalamus5.46 ± 0.32
Temporal Lobe5.53 ± 0.36
Thalamus5.41 ± 0.35
White Matter6.74 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AW146020CBCerebellum1.9
2.31
AW146020CTXCerebral cortex2.35
3.32
AW146020HIPHippocampal region0.72
1.23
AW146020HPFHippocampal formation0.65
1.07
AW146020HYHypothalamus0.09
0.1
AW146020LSXLateral septal complex0.11
0.19
AW146020MBMidbrain0.29
0.45
AW146020MYMedulla0.44
0.48
AW146020OLFOlfactory bulb2.72
3.24
AW146020PPons0.19
0.18
AW146020PALPallidum0.19
0.21
AW146020RHPRetrohippocampal region0.51
0.76
AW146020sAMYStriatum-like amygdalar nuclei0.11
0.06
AW146020STRStriatum0.23
0.28
AW146020STRdStriatum dorsal region0.25
0.34
AW146020STRvStriatum ventral region0.25
0.21
AW146020THThalamus0.43
0.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GCF_HUMAN_67 6 67 72 LLSLGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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