AutismKB 2.0

Annotation Detail for BTG1


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Basic Information Top
Gene Symbol:BTG1 ( - )
Gene Full Name: B-cell translocation gene 1, anti-proliferative
Band: 12q21.33
Quick LinksEntrez ID:694; OMIM: 109580; Uniprot ID:BTG1_HUMAN; ENSEMBL ID: ENSG00000133639; HGNC ID: 1130
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst5 / 6231980
fetus100 / 564012177
neonate2 / 3109764
infant3 / 23620127
juvenile10 / 55556179
adult267 / 1939121137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma33 / 82823398
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor16 / 119369134
germ cell tumor16 / 26384560
glioma28 / 106883261
head and neck tumor6 / 13630244
kidney tumor5 / 6895972
leukemia31 / 95842323
liver tumor5 / 9635951
lung tumor10 / 10312796
lymphoma21 / 71755292
non-neoplasia26 / 97250267
normal483 / 3360307143
ovarian tumor7 / 7668291
pancreatic tumor45 / 104616430
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer7 / 10268068
retinoblastoma3 / 4635664
skin tumor13 / 124949104
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites6 / 40015149
bladder3 / 29757100
blood21 / 123478170
bone24 / 71655334
bone marrow2 / 4880140
brain89 / 110098980
cervix7 / 48171145
connective tissue46 / 149255308
ear5 / 16212308
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye41 / 211054194
heart26 / 89626290
intestine27 / 234472115
kidney30 / 211777141
larynx0 / 241450 
liver24 / 207743115
lung97 / 336974287
lymph2 / 4427045
lymph node38 / 91610414
mammary gland11 / 15327171
mouth2 / 6705229
muscle3 / 10771527
nerve4 / 15768253
ovary6 / 10205158
pancreas96 / 214812446
parathyroid9 / 20539438
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta30 / 280825106
prostate13 / 18934568
salivary gland4 / 20155198
skin25 / 210574118
spleen11 / 53952203
stomach16 / 96619165
testis19 / 33044257
thymus9 / 81131110
thyroid0 / 474730 
tonsil8 / 16999470
trachea0 / 524130 
umbilical cord0 / 136800 
uterus32 / 232878137
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200920_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts922.25
Adipocyte704.65
AdrenalCortex315.4
Adrenalgland425.45
Amygdala152.65
Appendix261.9
AtrioventricularNode59.95
BDCA4+_DentriticCells2433.7
Bonemarrow1358.75
BronchialEpithelialCells497.35
CD105+_Endothelial217
CD14+_Monocytes2911.65
CD19+_BCells(neg._sel.)6541.55
CD33+_Myeloid3174.25
CD34+585.45
CD4+_Tcells5630.75
CD56+_NKCells4970.55
CD71+_EarlyErythroid35.6
CD8+_Tcells4839.65
CardiacMyocytes173.1
Caudatenucleus31.9
Cerebellum612.9
CerebellumPeduncles759.05
CiliaryGanglion177.45
CingulateCortex23.8
Colorectaladenocarcinoma119.75
DorsalRootGanglion129.4
FetalThyroid147.25
Fetalbrain157.7
Fetalliver287.25
Fetallung765.4
GlobusPallidus17.2
Heart254.15
Hypothalamus47.4
Kidney328.2
Leukemia_chronicMyelogenousK-56255.6
Leukemia_promyelocytic-HL-6079.2
Leukemialymphoblastic(MOLT-4)108.45
Liver570.2
Lung4268.65
Lymphnode1293.65
Lymphoma_burkitts(Daudi)367.75
Lymphoma_burkitts(Raji)789.5
MedullaOblongata23.7
OccipitalLobe40.85
OlfactoryBulb447.4
Ovary378
Pancreas393.2
PancreaticIslet813.9
ParietalLobe22.65
Pituitary394.7
Placenta707.95
Pons34.3
PrefrontalCortex118.9
Prostate2233.25
Salivarygland420
SkeletalMuscle27.4
Skin671.75
SmoothMuscle203.05
Spinalcord111.9
SubthalamicNucleus25.2
SuperiorCervicalGanglion49.3
TemporalLobe61.05
Testis199.35
TestisGermCell179.1
TestisIntersitial121.15
TestisLeydigCell63.55
TestisSeminiferousTubule135.35
Thalamus30
Thymus2121.85
Thyroid524.6
Tongue99.8
Tonsil1245.65
Trachea500.65
TrigeminalGanglion77.95
Uterus1561.45
UterusCorpus320.3
WholeBlood2801.5
Wholebrain126.05
colon884.75
pineal_day636.9
pineal_night629.68
retina421.025
small_intestine608.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P225870
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.88 ± 1.1
Basal Forebrain2.42 ± 0.39
Basal Part of Pons2.12 ± 0.69
Cerebellar Cortex3.3 ± 0.45
Cerebellar Nuclei2.73 ± 0.74
Claustrum3.17 ± 0.77
Epithalamus2.19 ± 0.66
Frontal Lobe2.25 ± 0.75
Globus Pallidus2.49 ± 0.75
Hypothalamus2.69 ± 1.01
Insula2.36 ± 0.59
Limbic Lobe2.48 ± 0.69
Mesencephalon2.63 ± 0.77
Myelencephalon2.47 ± 0.67
Occipital Lobe2.78 ± 0.79
Parietal Lobe2.47 ± 0.74
Pontine Tegmentum2.55 ± 0.78
Striatum2.28 ± 0.8
Subthalamus2.65 ± 0.73
Temporal Lobe2.34 ± 0.71
Thalamus2.39 ± 0.68
White Matter2.7 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Btg1CBCerebellum100
100
Btg1CTXCerebral cortex18.69
14.31
Btg1HIPHippocampal region62.58
93.7
Btg1HPFHippocampal formation51.97
67.23
Btg1HYHypothalamus19.09
16.8
Btg1LSXLateral septal complex27.01
34.9
Btg1MBMidbrain16.41
14.76
Btg1MYMedulla35.46
43.81
Btg1OLFOlfactory bulb48.23
64
Btg1PPons17.66
17.48
Btg1PALPallidum22.18
24.86
Btg1RHPRetrohippocampal region37.79
33.87
Btg1sAMYStriatum-like amygdalar nuclei36.95
30.85
Btg1STRStriatum32.66
30.76
Btg1STRdStriatum dorsal region20
17.57
Btg1STRvStriatum ventral region68.41
61.54
Btg1THThalamus11.61
12.82
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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