AutismKB 2.0

Annotation Detail for TEAD1


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Basic Information Top
Gene Symbol:TEAD1 ( AA,FLJ17970,NTEF-1,REF1,TCF-13,TCF13,TEAD-1,TEF-1 )
Gene Full Name: TEA domain family member 1 (SV40 transcriptional enhancer factor)
Band: 11p15.3
Quick LinksEntrez ID:7003; OMIM: 189967; Uniprot ID:TEAD1_HUMAN; ENSEMBL ID: ENSG00000187079; HGNC ID: 11714
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst8 / 62319128
fetus54 / 56401295
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma11 / 82823132
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal196 / 336030758
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone5 / 7165569
bone marrow3 / 4880161
brain23 / 110098920
cervix5 / 48171103
connective tissue11 / 14925573
ear3 / 16212185
embryonic tissue28 / 215722129
esophagus0 / 202090 
eye11 / 21105452
heart10 / 89626111
intestine8 / 23447234
kidney9 / 21177742
larynx0 / 241450 
liver12 / 20774357
lung22 / 33697465
lymph0 / 442700 
lymph node1 / 9161010
mammary gland10 / 15327165
mouth3 / 6705244
muscle7 / 10771564
nerve1 / 1576863
ovary4 / 10205139
pancreas14 / 21481265
parathyroid7 / 20539340
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta16 / 28082556
prostate3 / 18934515
salivary gland0 / 201550 
skin27 / 210574128
spleen0 / 539520 
stomach2 / 9661920
testis9 / 33044227
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214600_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.95
AdrenalCortex10.35
Adrenalgland6.15
Amygdala6.7
Appendix8.1
AtrioventricularNode6.3
BDCA4+_DentriticCells6.4
Bonemarrow7.5
BronchialEpithelialCells6.2
CD105+_Endothelial6.35
CD14+_Monocytes6.95
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid7.7
CD34+7.5
CD4+_Tcells6.35
CD56+_NKCells6.8
CD71+_EarlyErythroid6.4
CD8+_Tcells5.55
CardiacMyocytes10
Caudatenucleus6
Cerebellum5.5
CerebellumPeduncles8.25
CiliaryGanglion5.6
CingulateCortex7.05
Colorectaladenocarcinoma6.65
DorsalRootGanglion6.2
FetalThyroid6.95
Fetalbrain6.1
Fetalliver6
Fetallung5.15
GlobusPallidus6
Heart11.4
Hypothalamus6.85
Kidney6.5
Leukemia_chronicMyelogenousK-5625.9
Leukemia_promyelocytic-HL-605.8
Leukemialymphoblastic(MOLT-4)4.85
Liver10.85
Lung7.2
Lymphnode5.4
Lymphoma_burkitts(Daudi)8.7
Lymphoma_burkitts(Raji)10.4
MedullaOblongata5.95
OccipitalLobe5.85
OlfactoryBulb5.15
Ovary5.55
Pancreas5.7
PancreaticIslet7.25
ParietalLobe8.05
Pituitary7.65
Placenta6.5
Pons7.65
PrefrontalCortex7.9
Prostate7.55
Salivarygland5.55
SkeletalMuscle12.25
Skin6
SmoothMuscle7.4
Spinalcord7.05
SubthalamicNucleus8.9
SuperiorCervicalGanglion11.9
TemporalLobe6.35
Testis5.65
TestisGermCell5.25
TestisIntersitial5.65
TestisLeydigCell6.85
TestisSeminiferousTubule5.65
Thalamus6.95
Thymus4.9
Thyroid8
Tongue8.9
Tonsil6.85
Trachea5.5
TrigeminalGanglion7.5
Uterus5.5
UterusCorpus6.55
WholeBlood6.95
Wholebrain5.25
colon12.45
pineal_day7.96
pineal_night8
retina8.55
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P362893
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.16 ± 0.25
Basal Forebrain8.27 ± 0.33
Basal Part of Pons7.37 ± 0.23
Cerebellar Cortex7.85 ± 0.25
Cerebellar Nuclei7.73 ± 0.31
Claustrum7.9 ± 0.38
Epithalamus8.98 ± 0.52
Frontal Lobe7.94 ± 0.33
Globus Pallidus9.3 ± 0.47
Hypothalamus8.43 ± 0.24
Insula7.83 ± 0.23
Limbic Lobe8.26 ± 0.48
Mesencephalon8.31 ± 0.35
Myelencephalon8.22 ± 0.49
Occipital Lobe8.4 ± 0.39
Parietal Lobe8.13 ± 0.45
Pontine Tegmentum8.19 ± 0.26
Striatum8.64 ± 0.39
Subthalamus7.8 ± 0.23
Temporal Lobe7.97 ± 0.26
Thalamus8.17 ± 0.28
White Matter8.89 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tead1CBCerebellum33.55
57.82
Tead1CTXCerebral cortex28.89
29.75
Tead1HIPHippocampal region31.41
45.13
Tead1HPFHippocampal formation29.08
35.23
Tead1HYHypothalamus9.63
8.34
Tead1LSXLateral septal complex4.89
5.39
Tead1MBMidbrain13.84
14.68
Tead1MYMedulla32.88
43.42
Tead1OLFOlfactory bulb25.6
23.83
Tead1PPons19.4
23.01
Tead1PALPallidum5.15
4.89
Tead1RHPRetrohippocampal region23.85
18.86
Tead1sAMYStriatum-like amygdalar nuclei10.64
8.53
Tead1STRStriatum4.3
3.89
Tead1STRdStriatum dorsal region3.03
2.99
Tead1STRvStriatum ventral region3.82
2.69
Tead1THThalamus12.44
14.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063699 22 103 124 ALQHMAAMSSAQIVSATAIHNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018