AutismKB 2.0

Annotation Detail for TECTA


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Basic Information Top
Gene Symbol:TECTA ( DFNA12,DFNA8,DFNB21 )
Gene Full Name: tectorin alpha
Band: 11q23.3
Quick LinksEntrez ID:7007; OMIM: 602574; Uniprot ID:TECTA_HUMAN; ENSEMBL ID: ENSG00000109927; HGNC ID: 11720
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal14 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221296_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.4
AdrenalCortex4.85
Adrenalgland3.8
Amygdala4.65
Appendix4.55
AtrioventricularNode3.45
BDCA4+_DentriticCells4.85
Bonemarrow4.55
BronchialEpithelialCells4.35
CD105+_Endothelial4.5
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)4.75
CD33+_Myeloid5.7
CD34+5.65
CD4+_Tcells4.8
CD56+_NKCells5.25
CD71+_EarlyErythroid4.15
CD8+_Tcells4.25
CardiacMyocytes5.9
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5.15
CiliaryGanglion3.2
CingulateCortex4.55
Colorectaladenocarcinoma4.45
DorsalRootGanglion3.4
FetalThyroid4.3
Fetalbrain4.4
Fetalliver3.85
Fetallung3.6
GlobusPallidus3.4
Heart5.85
Hypothalamus4.85
Kidney3.65
Leukemia_chronicMyelogenousK-5624
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.55
Liver6
Lung4.8
Lymphnode3.75
Lymphoma_burkitts(Daudi)5.7
Lymphoma_burkitts(Raji)6.3
MedullaOblongata4.1
OccipitalLobe3.95
OlfactoryBulb3.55
Ovary2.95
Pancreas3.6
PancreaticIslet4.7
ParietalLobe4.85
Pituitary5.2
Placenta4.55
Pons4.3
PrefrontalCortex5.5
Prostate5.2
Salivarygland3.6
SkeletalMuscle5.7
Skin3.45
SmoothMuscle5
Spinalcord4.75
SubthalamicNucleus4.05
SuperiorCervicalGanglion5.15
TemporalLobe4.1
Testis3.8
TestisGermCell3.7
TestisIntersitial3.75
TestisLeydigCell4.4
TestisSeminiferousTubule3.85
Thalamus4.55
Thymus3.5
Thyroid5.55
Tongue4.4
Tonsil4.35
Trachea3.7
TrigeminalGanglion4.55
Uterus3.65
UterusCorpus4.05
WholeBlood4.8
Wholebrain3.7
colon4.5
pineal_day5.52
pineal_night5.42
retina5.375
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12339_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.59 ± 1.36
Basal Forebrain1.99 ± 0.72
Basal Part of Pons2.09 ± 0.79
Cerebellar Cortex1.66 ± 0.64
Cerebellar Nuclei2.28 ± 0.67
Claustrum2.46 ± 0.79
Epithalamus1.72 ± 0.88
Frontal Lobe2.18 ± 0.76
Globus Pallidus1.7 ± 0.56
Hypothalamus1.9 ± 0.53
Insula1.94 ± 0.8
Limbic Lobe2.15 ± 0.79
Mesencephalon2.2 ± 0.75
Myelencephalon2.1 ± 0.75
Occipital Lobe2.19 ± 0.82
Parietal Lobe2.03 ± 0.86
Pontine Tegmentum2.1 ± 0.84
Striatum3.13 ± 0.61
Subthalamus2.18 ± 0.66
Temporal Lobe1.82 ± 0.77
Thalamus1.95 ± 0.76
White Matter1.58 ± 0.11
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018