AutismKB 2.0

Annotation Detail for TMBIM6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TMBIM6 ( BAXI1,BI-1,TEGT )
Gene Full Name: transmembrane BAX inhibitor motif containing 6
Band: 12q13.12
Quick LinksEntrez ID:7009; OMIM: 600748; Uniprot ID:BI1_HUMAN; ENSEMBL ID: ENSG00000139644; HGNC ID: 11723
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst12 / 62319192
fetus78 / 564012138
neonate0 / 310970 
infant5 / 23620211
juvenile13 / 55556233
adult784 / 1939121404
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor22 / 127941719
bladder carcinoma5 / 17475286
breast (mammary gland) tumor28 / 94178297
cervical tumor18 / 34366523
chondrosarcoma0 / 828230 
colorectal tumor102 / 114246892
esophageal tumor1 / 1729057
gastrointestinal tumor42 / 119369351
germ cell tumor78 / 263845295
glioma18 / 106883168
head and neck tumor66 / 136302484
kidney tumor22 / 68959319
leukemia36 / 95842375
liver tumor16 / 96359166
lung tumor39 / 103127378
lymphoma6 / 7175583
non-neoplasia104 / 972501069
normal655 / 3360307194
ovarian tumor47 / 76682612
pancreatic tumor56 / 104616535
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer44 / 102680428
retinoblastoma8 / 46356172
skin tumor30 / 124949240
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor50 / 90257553
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland31 / 33197933
ascites14 / 40015349
bladder10 / 29757336
blood19 / 123478153
bone16 / 71655223
bone marrow11 / 48801225
brain114 / 1100989103
cervix19 / 48171394
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue46 / 215722213
esophagus1 / 2020949
eye54 / 211054255
heart13 / 89626145
intestine149 / 234472635
kidney62 / 211777292
larynx3 / 24145124
liver47 / 207743226
lung89 / 336974264
lymph2 / 4427045
lymph node6 / 9161065
mammary gland65 / 153271424
mouth6 / 6705289
muscle5 / 10771546
nerve9 / 15768570
ovary52 / 102051509
pancreas100 / 214812465
parathyroid4 / 20539194
pharynx5 / 41328120
pituitary gland6 / 16585361
placenta73 / 280825259
prostate64 / 189345338
salivary gland6 / 20155297
skin51 / 210574242
spleen10 / 53952185
stomach42 / 96619434
testis78 / 330442236
thymus5 / 8113161
thyroid149 / 474733138
tonsil3 / 16999176
trachea1 / 5241319
umbilical cord0 / 136800 
uterus107 / 232878459
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200803_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts895.75
Adipocyte585.7
AdrenalCortex127.7
Adrenalgland461.5
Amygdala79.55
Appendix76.2
AtrioventricularNode44.35
BDCA4+_DentriticCells1402.5
Bonemarrow634.75
BronchialEpithelialCells1283.85
CD105+_Endothelial386.1
CD14+_Monocytes852.05
CD19+_BCells(neg._sel.)480.7
CD33+_Myeloid1160.1
CD34+476.2
CD4+_Tcells598.4
CD56+_NKCells1120.15
CD71+_EarlyErythroid783
CD8+_Tcells588.65
CardiacMyocytes678.75
Caudatenucleus77.15
Cerebellum151
CerebellumPeduncles253.45
CiliaryGanglion44.35
CingulateCortex45.25
Colorectaladenocarcinoma154.65
DorsalRootGanglion73.1
FetalThyroid228.35
Fetalbrain56.4
Fetalliver773.35
Fetallung390.7
GlobusPallidus80.25
Heart136.9
Hypothalamus235.4
Kidney1014
Leukemia_chronicMyelogenousK-562177.85
Leukemia_promyelocytic-HL-60120.25
Leukemialymphoblastic(MOLT-4)328
Liver765.85
Lung352.15
Lymphnode268.3
Lymphoma_burkitts(Daudi)179.2
Lymphoma_burkitts(Raji)33.6
MedullaOblongata131.65
OccipitalLobe251
OlfactoryBulb150.3
Ovary159.95
Pancreas486.05
PancreaticIslet764.3
ParietalLobe157.9
Pituitary194.75
Placenta1223.05
Pons44.4
PrefrontalCortex132.15
Prostate122.2
Salivarygland183.6
SkeletalMuscle8.2
Skin64.4
SmoothMuscle809.45
Spinalcord137.7
SubthalamicNucleus61.1
SuperiorCervicalGanglion74.6
TemporalLobe55.35
Testis1230.45
TestisGermCell762.55
TestisIntersitial920.4
TestisLeydigCell671.35
TestisSeminiferousTubule554.8
Thalamus43.15
Thymus519.95
Thyroid217.5
Tongue97.3
Tonsil303.6
Trachea543.1
TrigeminalGanglion5.8
Uterus56.5
UterusCorpus202.6
WholeBlood919.55
Wholebrain104.95
colon853.2
pineal_day189.72
pineal_night307.44
retina472.975
small_intestine684.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P204702
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.68 ± 0.23
Basal Forebrain9.63 ± 0.13
Basal Part of Pons9.22 ± 0.19
Cerebellar Cortex9.31 ± 0.2
Cerebellar Nuclei9.75 ± 0.5
Claustrum9.49 ± 0.34
Epithalamus9.82 ± 0.25
Frontal Lobe9.52 ± 0.32
Globus Pallidus10.37 ± 0.25
Hypothalamus9.71 ± 0.38
Insula9.39 ± 0.21
Limbic Lobe9.46 ± 0.32
Mesencephalon9.67 ± 0.27
Myelencephalon9.59 ± 0.33
Occipital Lobe9.54 ± 0.35
Parietal Lobe9.49 ± 0.25
Pontine Tegmentum9.65 ± 0.29
Striatum9.77 ± 0.34
Subthalamus9.29 ± 0.18
Temporal Lobe9.45 ± 0.26
Thalamus9.69 ± 0.24
White Matter10.59 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TegtCBCerebellum9.26
23.97
TegtCTXCerebral cortex60.42
60.57
TegtHIPHippocampal region100
100
TegtHPFHippocampal formation93.95
100
TegtHYHypothalamus100
100
TegtLSXLateral septal complex74.83
74.46
TegtMBMidbrain36.52
45.68
TegtMYMedulla13.56
24.7
TegtOLFOlfactory bulb42.45
57.2
TegtPPons36.88
52.38
TegtPALPallidum68.54
86.89
TegtRHPRetrohippocampal region58.59
64.38
TegtsAMYStriatum-like amygdalar nuclei100
100
TegtSTRStriatum69.37
73.44
TegtSTRdStriatum dorsal region67.64
70.78
TegtSTRvStriatum ventral region48.64
54.76
TegtTHThalamus69.1
77.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved