AutismKB 2.0

Annotation Detail for TERT


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Basic Information Top
Gene Symbol:TERT ( EST2,TCS1,TP2,TRT,hEST2 )
Gene Full Name: telomerase reverse transcriptase
Band: 5p15.33
Quick LinksEntrez ID:7015; OMIM: 187270; Uniprot ID:TERT_HUMAN; ENSEMBL ID: ENSG00000164362; HGNC ID: 11730
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal4 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph5 / 44270112
lymph node3 / 9161032
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207199_at
Cell line Expression level Expression bar
721_B_lymphoblasts78.55
Adipocyte48.1
AdrenalCortex57.65
Adrenalgland45.4
Amygdala55.65
Appendix53.8
AtrioventricularNode55.15
BDCA4+_DentriticCells48.95
Bonemarrow60.4
BronchialEpithelialCells44.15
CD105+_Endothelial51
CD14+_Monocytes54.35
CD19+_BCells(neg._sel.)55.7
CD33+_Myeloid61.1
CD34+67.5
CD4+_Tcells58.8
CD56+_NKCells52.85
CD71+_EarlyErythroid49.25
CD8+_Tcells50.6
CardiacMyocytes67.65
Caudatenucleus68
Cerebellum42.5
CerebellumPeduncles64.1
CiliaryGanglion68.9
CingulateCortex54
Colorectaladenocarcinoma53.7
DorsalRootGanglion44.75
FetalThyroid51.1
Fetalbrain57.6
Fetalliver50.25
Fetallung43.05
GlobusPallidus46.55
Heart97.4
Hypothalamus51.85
Kidney43.6
Leukemia_chronicMyelogenousK-56248.4
Leukemia_promyelocytic-HL-6047.5
Leukemialymphoblastic(MOLT-4)39.9
Liver75.15
Lung73.05
Lymphnode46.3
Lymphoma_burkitts(Daudi)68.4
Lymphoma_burkitts(Raji)82.05
MedullaOblongata47.1
OccipitalLobe48.15
OlfactoryBulb42.55
Ovary40.5
Pancreas42.9
PancreaticIslet57.25
ParietalLobe75.3
Pituitary62.1
Placenta47.8
Pons53.6
PrefrontalCortex64.15
Prostate57.9
Salivarygland44.7
SkeletalMuscle108.1
Skin55.25
SmoothMuscle49.55
Spinalcord57
SubthalamicNucleus58.8
SuperiorCervicalGanglion71.2
TemporalLobe47.75
Testis46.05
TestisGermCell42.5
TestisIntersitial44.55
TestisLeydigCell55.3
TestisSeminiferousTubule45.5
Thalamus53.85
Thymus43.6
Thyroid65.5
Tongue69.25
Tonsil52.2
Trachea44.75
TrigeminalGanglion73.6
Uterus44.2
UterusCorpus52.75
WholeBlood52.6
Wholebrain45.7
colon54.2
pineal_day80.26
pineal_night91.48
retina65.125
small_intestine52.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16205_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 0.94
Basal Forebrain1.7 ± 0.18
Basal Part of Pons1.49 ± 0.43
Cerebellar Cortex1.58 ± 0.67
Cerebellar Nuclei2.05 ± 0.73
Claustrum2.65 ± 0.9
Epithalamus1.43 ± 0.75
Frontal Lobe1.62 ± 0.62
Globus Pallidus2.33 ± 0.3
Hypothalamus1.92 ± 0.57
Insula1.54 ± 0.43
Limbic Lobe1.84 ± 0.73
Mesencephalon1.97 ± 0.76
Myelencephalon1.85 ± 0.71
Occipital Lobe1.93 ± 0.66
Parietal Lobe1.86 ± 0.81
Pontine Tegmentum1.86 ± 0.71
Striatum2.09 ± 0.9
Subthalamus1.94 ± 0.74
Temporal Lobe1.72 ± 0.66
Thalamus1.72 ± 0.59
White Matter2.22 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TertCBCerebellum17.32
22.84
TertCTXCerebral cortex23.22
16.16
TertHIPHippocampal region13.86
12.99
TertHPFHippocampal formation19.23
16.33
TertHYHypothalamus6.71
4.79
TertLSXLateral septal complex5.12
3.52
TertMBMidbrain4.25
3.84
TertMYMedulla8.02
8.55
TertOLFOlfactory bulb19.53
14.25
TertPPons8.92
10.73
TertPALPallidum12.25
10.91
TertRHPRetrohippocampal region30.25
22.29
TertsAMYStriatum-like amygdalar nuclei25.78
18
TertSTRStriatum11.28
7.98
TertSTRdStriatum dorsal region10.8
7.77
TertSTRvStriatum ventral region9.69
6.66
TertTHThalamus13.27
11.83
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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