Annotation Detail for TFAM
Basic Information Top
| Gene Symbol: | TFAM ( MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA ) |
|---|---|
| Gene Full Name: | transcription factor A, mitochondrial |
| Band: | 10q21.1 |
| Quick Links | Entrez ID:7019; OMIM: 600438; Uniprot ID:TFAM_HUMAN; ENSEMBL ID: ENSG00000108064; HGNC ID: 11741 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.642966
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 29 / 564012 | 51 | |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 64 / 1939121 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 4 / 17290 | 231 |  |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 18 / 263845 | 68 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 10 / 95842 | 104 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 157 / 3360307 | 46 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 2 / 29757 | 67 | |
| blood | 14 / 123478 | 113 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 31 / 1100989 | 28 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 4 / 20209 | 197 | |
| eye | 3 / 211054 | 14 | |
| heart | 8 / 89626 | 89 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 12 / 207743 | 57 | |
| lung | 8 / 336974 | 23 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 7 / 91610 | 76 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 4 / 41328 | 96 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 14 / 280825 | 49 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 27 / 330442 | 81 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 208541_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 127.15 | |
| Adipocyte | 8.85 | |
| AdrenalCortex | 10 | |
| Adrenalgland | 7.75 | |
| Amygdala | 6.6 | |
| Appendix | 7.4 | |
| AtrioventricularNode | 7.75 | |
| BDCA4+_DentriticCells | 52.75 | |
| Bonemarrow | 11.2 | |
| BronchialEpithelialCells | 7.5 | |
| CD105+_Endothelial | 59.95 | |
| CD14+_Monocytes | 29.25 | |
| CD19+_BCells(neg._sel.) | 100.35 | |
| CD33+_Myeloid | 72.05 | |
| CD34+ | 94.1 | |
| CD4+_Tcells | 42.1 | |
| CD56+_NKCells | 90.8 | |
| CD71+_EarlyErythroid | 16.4 | |
| CD8+_Tcells | 33 | |
| CardiacMyocytes | 15.95 | |
| Caudatenucleus | 7.85 | |
| Cerebellum | 7.25 | |
| CerebellumPeduncles | 14.25 | |
| CiliaryGanglion | 7.85 | |
| CingulateCortex | 11.25 | |
| Colorectaladenocarcinoma | 12.6 | |
| DorsalRootGanglion | 7.4 | |
| FetalThyroid | 10.45 | |
| Fetalbrain | 10.25 | |
| Fetalliver | 7.85 | |
| Fetallung | 5.15 | |
| GlobusPallidus | 8.7 | |
| Heart | 10.5 | |
| Hypothalamus | 8.05 | |
| Kidney | 8.65 | |
| Leukemia_chronicMyelogenousK-562 | 11.65 | |
| Leukemia_promyelocytic-HL-60 | 23 | |
| Leukemialymphoblastic(MOLT-4) | 11.8 | |
| Liver | 10.35 | |
| Lung | 12.8 | |
| Lymphnode | 9.1 | |
| Lymphoma_burkitts(Daudi) | 14.45 | |
| Lymphoma_burkitts(Raji) | 14.55 | |
| MedullaOblongata | 6.6 | |
| OccipitalLobe | 9.5 | |
| OlfactoryBulb | 7.1 | |
| Ovary | 7.95 | |
| Pancreas | 7.1 | |
| PancreaticIslet | 11.05 | |
| ParietalLobe | 9.7 | |
| Pituitary | 12.8 | |
| Placenta | 6.4 | |
| Pons | 10.55 | |
| PrefrontalCortex | 9.4 | |
| Prostate | 9.8 | |
| Salivarygland | 6.9 | |
| SkeletalMuscle | 10.35 | |
| Skin | 10.2 | |
| SmoothMuscle | 10.05 | |
| Spinalcord | 9.55 | |
| SubthalamicNucleus | 8.55 | |
| SuperiorCervicalGanglion | 8.1 | |
| TemporalLobe | 6.7 | |
| Testis | 8.35 | |
| TestisGermCell | 32.8 | |
| TestisIntersitial | 22.45 | |
| TestisLeydigCell | 18 | |
| TestisSeminiferousTubule | 14.05 | |
| Thalamus | 9.75 | |
| Thymus | 9.05 | |
| Thyroid | 12.55 | |
| Tongue | 9.3 | |
| Tonsil | 9.9 | |
| Trachea | 7.9 | |
| TrigeminalGanglion | 10.3 | |
| Uterus | 5.55 | |
| UterusCorpus | 7.6 | |
| WholeBlood | 9.75 | |
| Wholebrain | 5.3 | |
| colon | 12.95 | |
| pineal_day | 19.16 | |
| pineal_night | 14.56 | |
| retina | 9.725 | |
| small_intestine | 9.9 | |
- Probe name: A_23_P414771
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 9.63 ± 0.08 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 9.71 ± 0.11 | |
| Basal Part of Pons | 9.57 ± 0.17 | |
| Cerebellar Cortex | 9.91 ± 0.18 | |
| Cerebellar Nuclei | 9.91 ± 0.26 | |
| Claustrum | 9.29 ± 0.26 | |
| Epithalamus | 9.97 ± 0.13 | |
| Frontal Lobe | 9.64 ± 0.25 | |
| Globus Pallidus | 9.73 ± 0.17 | |
| Hypothalamus | 9.99 ± 0.23 | |
| Insula | 9.63 ± 0.26 | |
| Limbic Lobe | 9.58 ± 0.19 | |
| Mesencephalon | 9.7 ± 0.21 | |
| Myelencephalon | 9.66 ± 0.22 | |
| Occipital Lobe | 9.78 ± 0.18 | |
| Parietal Lobe | 9.7 ± 0.2 | |
| Pontine Tegmentum | 9.74 ± 0.22 | |
| Striatum | 9.6 ± 0.22 | |
| Subthalamus | 9.7 ± 0.19 | |
| Temporal Lobe | 9.67 ± 0.23 | |
| Thalamus | 9.63 ± 0.17 | |
| White Matter | 9.88 ± 0.18 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Tfam | CB | Cerebellum | 42.26 | |
| 77.8 | | |||
| Tfam | CTX | Cerebral cortex | 99.03 | |
| 93.01 | | |||
| Tfam | HIP | Hippocampal region | 60.09 | |
| 96.53 | | |||
| Tfam | HPF | Hippocampal formation | 74.15 | |
| 95.16 | | |||
| Tfam | HY | Hypothalamus | 44.34 | |
| 42.93 | | |||
| Tfam | LSX | Lateral septal complex | 45.99 | |
| 38.94 | | |||
| Tfam | MB | Midbrain | 53.89 | |
| 60.01 | | |||
| Tfam | MY | Medulla | 53.05 | |
| 77.34 | | |||
| Tfam | OLF | Olfactory bulb | 72.35 | |
| 70.16 | | |||
| Tfam | P | Pons | 46.73 | |
| 63.04 | | |||
| Tfam | PAL | Pallidum | 35.98 | |
| 35.24 | | |||
| Tfam | RHP | Retrohippocampal region | 91.32 | |
| 93.96 | | |||
| Tfam | sAMY | Striatum-like amygdalar nuclei | 50.19 | |
| 45.41 | | |||
| Tfam | STR | Striatum | 41.03 | |
| 34.37 | | |||
| Tfam | STRd | Striatum dorsal region | 35.41 | |
| 28.79 | | |||
| Tfam | STRv | Striatum ventral region | 50.68 | |
| 41.33 | | |||
| Tfam | TH | Thalamus | 53.86 | |
| 55.4 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00037446 | 10 | 160 | 169 | SAYNVYVAER | Peptide Atlas |
| TFAM_HUMAN_117 | 15 | 117 | 131 | FKEQLTPSQIMSLEK | PRIDE |
| TFAM_HUMAN_159 | 10 | 159 | 168 | SAYNVYVAER | PRIDE |
| TFAM_HUMAN_190 | 20 | 190 | 209 | NLSDSEKELYIQHAKEDETR | PRIDE |