AutismKB 2.0

Annotation Detail for NR2F2


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Basic Information Top
Gene Symbol:NR2F2 ( ARP1,COUPTFB,COUPTFII,MGC117452,SVP40,TFCOUP2 )
Gene Full Name: nuclear receptor subfamily 2, group F, member 2
Band: 15q26.2
Quick LinksEntrez ID:7026; OMIM: 107773; Uniprot ID:COT2_HUMAN; ENSEMBL ID: ENSG00000185551; HGNC ID: 7976
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body28 / 70761395
blastocyst1 / 6231916
fetus60 / 564012106
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult109 / 193912156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor4 / 26384515
glioma10 / 10688393
head and neck tumor3 / 13630222
kidney tumor9 / 68959130
leukemia1 / 9584210
liver tumor6 / 9635962
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal239 / 336030771
ovarian tumor2 / 7668226
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain48 / 110098943
cervix5 / 48171103
connective tissue13 / 14925587
ear7 / 16212431
embryonic tissue43 / 215722199
esophagus0 / 202090 
eye7 / 21105433
heart6 / 8962666
intestine3 / 23447212
kidney24 / 211777113
larynx0 / 241450 
liver9 / 20774343
lung24 / 33697471
lymph0 / 442700 
lymph node1 / 9161010
mammary gland14 / 15327191
mouth1 / 6705214
muscle5 / 10771546
nerve2 / 15768126
ovary4 / 10205139
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta19 / 28082567
prostate13 / 18934568
salivary gland0 / 201550 
skin7 / 21057433
spleen4 / 5395274
stomach8 / 9661982
testis7 / 33044221
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus15 / 23287864
vascular3 / 5178057
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209120_at
Cell line Expression level Expression bar
721_B_lymphoblasts145.8
Adipocyte157.55
AdrenalCortex39.2
Adrenalgland203.8
Amygdala312.9
Appendix89.05
AtrioventricularNode47.65
BDCA4+_DentriticCells8.55
Bonemarrow13.85
BronchialEpithelialCells91.85
CD105+_Endothelial16.4
CD14+_Monocytes13.4
CD19+_BCells(neg._sel.)11.85
CD33+_Myeloid14.35
CD34+12.05
CD4+_Tcells8.1
CD56+_NKCells10.25
CD71+_EarlyErythroid10.9
CD8+_Tcells8.85
CardiacMyocytes97.7
Caudatenucleus13.45
Cerebellum21.05
CerebellumPeduncles20.8
CiliaryGanglion29
CingulateCortex13.55
Colorectaladenocarcinoma83.9
DorsalRootGanglion90.55
FetalThyroid50.95
Fetalbrain62.9
Fetalliver88.8
Fetallung263.05
GlobusPallidus9.8
Heart46.05
Hypothalamus114.75
Kidney146.6
Leukemia_chronicMyelogenousK-562165.7
Leukemia_promyelocytic-HL-609.35
Leukemialymphoblastic(MOLT-4)6.8
Liver70.85
Lung258.9
Lymphnode202.5
Lymphoma_burkitts(Daudi)15.75
Lymphoma_burkitts(Raji)17.5
MedullaOblongata9.25
OccipitalLobe15.8
OlfactoryBulb205.7
Ovary158.7
Pancreas42.6
PancreaticIslet101.5
ParietalLobe14
Pituitary59
Placenta251
Pons12.95
PrefrontalCortex20.3
Prostate508.95
Salivarygland40.25
SkeletalMuscle23.2
Skin32.8
SmoothMuscle162.75
Spinalcord88.7
SubthalamicNucleus16.3
SuperiorCervicalGanglion58.45
TemporalLobe12.35
Testis117.35
TestisGermCell158.6
TestisIntersitial62.65
TestisLeydigCell85.15
TestisSeminiferousTubule40.45
Thalamus56.2
Thymus28.3
Thyroid290.65
Tongue50.95
Tonsil23.95
Trachea262
TrigeminalGanglion39.75
Uterus1429.4
UterusCorpus42.9
WholeBlood12.65
Wholebrain23.65
colon365.15
pineal_day25.5
pineal_night37.72
retina723.125
small_intestine517.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_480_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.28 ± 0.82
Basal Forebrain6.59 ± 0.58
Basal Part of Pons5.76 ± 0.49
Cerebellar Cortex6.83 ± 0.68
Cerebellar Nuclei7 ± 0.54
Claustrum8.75 ± 0.8
Epithalamus7.35 ± 0.2
Frontal Lobe6.7 ± 0.65
Globus Pallidus8.27 ± 0.48
Hypothalamus7.33 ± 0.65
Insula7.03 ± 0.46
Limbic Lobe6.8 ± 0.84
Mesencephalon7.43 ± 0.76
Myelencephalon7.18 ± 0.72
Occipital Lobe7.47 ± 0.78
Parietal Lobe6.93 ± 0.62
Pontine Tegmentum7.65 ± 0.45
Striatum6.87 ± 0.56
Subthalamus6.5 ± 0.29
Temporal Lobe7.57 ± 0.73
Thalamus7.85 ± 0.63
White Matter6.1 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nr2f2CBCerebellum0
0
Nr2f2CTXCerebral cortex0
0
Nr2f2HIPHippocampal region0
0
Nr2f2HPFHippocampal formation0
0
Nr2f2HYHypothalamus0
0
Nr2f2LSXLateral septal complex0
0
Nr2f2MBMidbrain0
0
Nr2f2MYMedulla0
0
Nr2f2OLFOlfactory bulb0
0
Nr2f2PPons0
0
Nr2f2PALPallidum0
0
Nr2f2RHPRetrohippocampal region0
0
Nr2f2sAMYStriatum-like amygdalar nuclei0
0
Nr2f2STRStriatum0
0
Nr2f2STRdStriatum dorsal region0
0
Nr2f2STRvStriatum ventral region0
0
Nr2f2THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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