AutismKB 2.0

Annotation Detail for TFPI


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Basic Information Top
Gene Symbol:TFPI ( EPI,LACI,TFI,TFPI1 )
Gene Full Name: tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Band: 2q32.1
Quick LinksEntrez ID:7035; OMIM: 152310; Uniprot ID:TFPI1_HUMAN; ENSEMBL ID: ENSG00000003436; HGNC ID: 11760
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus39 / 56401269
neonate5 / 31097160
infant0 / 236200 
juvenile2 / 5555635
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma12 / 82823144
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma9 / 10688384
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor13 / 96359134
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal281 / 336030783
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone13 / 71655181
bone marrow2 / 4880140
brain16 / 110098914
cervix0 / 481710 
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye4 / 21105418
heart10 / 89626111
intestine5 / 23447221
kidney14 / 21177766
larynx0 / 241450 
liver32 / 207743154
lung21 / 33697462
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle7 / 10771564
nerve0 / 157680 
ovary1 / 1020519
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta149 / 280825530
prostate8 / 18934542
salivary gland1 / 2015549
skin1 / 2105744
spleen1 / 5395218
stomach3 / 9661931
testis3 / 3304429
thymus4 / 8113149
thyroid5 / 47473105
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord4 / 13680292
uterus5 / 23287821
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210664_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.2
Adipocyte29.5
AdrenalCortex24.55
Adrenalgland18.75
Amygdala16.05
Appendix40.4
AtrioventricularNode41.85
BDCA4+_DentriticCells13.95
Bonemarrow21.2
BronchialEpithelialCells19.6
CD105+_Endothelial20.3
CD14+_Monocytes13
CD19+_BCells(neg._sel.)16.9
CD33+_Myeloid19.65
CD34+22.1
CD4+_Tcells15.7
CD56+_NKCells16.1
CD71+_EarlyErythroid29.15
CD8+_Tcells10.9
CardiacMyocytes353.6
Caudatenucleus12.85
Cerebellum15.65
CerebellumPeduncles28.1
CiliaryGanglion30.05
CingulateCortex20.75
Colorectaladenocarcinoma17.9
DorsalRootGanglion28.5
FetalThyroid32.2
Fetalbrain14.55
Fetalliver110.4
Fetallung245.8
GlobusPallidus20
Heart35.25
Hypothalamus16.4
Kidney20.35
Leukemia_chronicMyelogenousK-562668.5
Leukemia_promyelocytic-HL-6015
Leukemialymphoblastic(MOLT-4)13.4
Liver76.85
Lung36.3
Lymphnode49.7
Lymphoma_burkitts(Daudi)20.75
Lymphoma_burkitts(Raji)27.45
MedullaOblongata13.15
OccipitalLobe13.6
OlfactoryBulb23.4
Ovary29.85
Pancreas21.9
PancreaticIslet91.15
ParietalLobe22.75
Pituitary21.65
Placenta1003.35
Pons22
PrefrontalCortex19.1
Prostate21.95
Salivarygland21.95
SkeletalMuscle69.7
Skin35.05
SmoothMuscle462.45
Spinalcord20.65
SubthalamicNucleus20.6
SuperiorCervicalGanglion72.5
TemporalLobe19.25
Testis14.25
TestisGermCell15.85
TestisIntersitial17.55
TestisLeydigCell19.9
TestisSeminiferousTubule17.45
Thalamus17.65
Thymus12.55
Thyroid33.25
Tongue54.1
Tonsil20.25
Trachea16.55
TrigeminalGanglion50.5
Uterus35
UterusCorpus46
WholeBlood18
Wholebrain11.5
colon19.3
pineal_day20.16
pineal_night18.56
retina20.125
small_intestine74.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P17095
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.65 ± 0.63
Basal Forebrain6.16 ± 0.34
Basal Part of Pons5.43 ± 0.33
Cerebellar Cortex5.73 ± 0.34
Cerebellar Nuclei6.73 ± 0.51
Claustrum5.25 ± 0.78
Epithalamus5.97 ± 0.45
Frontal Lobe5.84 ± 0.51
Globus Pallidus7.18 ± 0.41
Hypothalamus5.77 ± 0.35
Insula5.92 ± 0.48
Limbic Lobe5.85 ± 0.63
Mesencephalon5.97 ± 0.52
Myelencephalon6.17 ± 0.59
Occipital Lobe5.95 ± 0.57
Parietal Lobe5.87 ± 0.48
Pontine Tegmentum6.07 ± 0.46
Striatum6.86 ± 0.55
Subthalamus6.46 ± 0.25
Temporal Lobe5.8 ± 0.46
Thalamus6.13 ± 0.52
White Matter6.05 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TfpiCBCerebellum12.14
13.25
TfpiCTXCerebral cortex14.92
10.17
TfpiHIPHippocampal region10.85
10.49
TfpiHPFHippocampal formation11.77
11.02
TfpiHYHypothalamus25.52
18
TfpiLSXLateral septal complex20.49
13.57
TfpiMBMidbrain20.33
17.65
TfpiMYMedulla32.73
30.29
TfpiOLFOlfactory bulb27.77
19.86
TfpiPPons33.46
30.72
TfpiPALPallidum19.02
14.41
TfpiRHPRetrohippocampal region13.2
11.71
TfpisAMYStriatum-like amygdalar nuclei9
6.67
TfpiSTRStriatum12.61
8.5
TfpiSTRdStriatum dorsal region8.61
5.66
TfpiSTRvStriatum ventral region24.4
15.86
TfpiTHThalamus23.69
16.76
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010806 9 49 57 LMHSFCAFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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