AutismKB 2.0

Annotation Detail for TG


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Basic Information Top
Gene Symbol:TG ( AITD3,TGN )
Gene Full Name: thyroglobulin
Band: 8q24.22
Quick LinksEntrez ID:7038; OMIM: 188450; Uniprot ID:THYG_HUMAN; ENSEMBL ID: ENSG00000042832; HGNC ID: 11764
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult914 / 1939121471
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor482 / 1363023536
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia90 / 97250925
normal1070 / 3360307318
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine3 / 23447212
kidney1 / 2117774
larynx14 / 24145579
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth6 / 6705289
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate9 / 18934547
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid1585 / 4747333387
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203673_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.45
Adipocyte7.5
AdrenalCortex6.1
Adrenalgland6.5
Amygdala5.3
Appendix6.7
AtrioventricularNode9.5
BDCA4+_DentriticCells5.05
Bonemarrow5.65
BronchialEpithelialCells5.4
CD105+_Endothelial5.2
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.55
CD33+_Myeloid6.25
CD34+6.05
CD4+_Tcells5.75
CD56+_NKCells6.45
CD71+_EarlyErythroid5.25
CD8+_Tcells5
CardiacMyocytes7.65
Caudatenucleus7.4
Cerebellum5.45
CerebellumPeduncles7.4
CiliaryGanglion6.5
CingulateCortex12.15
Colorectaladenocarcinoma5.45
DorsalRootGanglion5.35
FetalThyroid10350.1
Fetalbrain5.45
Fetalliver4.9
Fetallung4.5
GlobusPallidus6.55
Heart7.55
Hypothalamus5.9
Kidney7.9
Leukemia_chronicMyelogenousK-5624.95
Leukemia_promyelocytic-HL-604.95
Leukemialymphoblastic(MOLT-4)4.45
Liver7.7
Lung5.4
Lymphnode271.25
Lymphoma_burkitts(Daudi)7.2
Lymphoma_burkitts(Raji)7.6
MedullaOblongata5.55
OccipitalLobe6.65
OlfactoryBulb6.85
Ovary3.75
Pancreas4.55
PancreaticIslet6.35
ParietalLobe9.3
Pituitary6.75
Placenta5.65
Pons13.55
PrefrontalCortex6.85
Prostate5.85
Salivarygland6.2
SkeletalMuscle19.8
Skin5.3
SmoothMuscle5.95
Spinalcord6
SubthalamicNucleus5.15
SuperiorCervicalGanglion10.05
TemporalLobe8.9
Testis5.15
TestisGermCell4.55
TestisIntersitial5.2
TestisLeydigCell6.2
TestisSeminiferousTubule7.45
Thalamus5.8
Thymus4.35
Thyroid18902.4
Tongue5.6
Tonsil5.75
Trachea40.1
TrigeminalGanglion5.8
Uterus4
UterusCorpus16.65
WholeBlood6
Wholebrain4.5
colon5.5
pineal_day6.58
pineal_night6.32
retina7.2
small_intestine5.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14018_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.5 ± 0.74
Basal Forebrain1.4 ± 0.18
Basal Part of Pons1.43 ± 0.48
Cerebellar Cortex1.49 ± 0.71
Cerebellar Nuclei1.91 ± 0.69
Claustrum2.62 ± 1.34
Epithalamus1.67 ± 0.94
Frontal Lobe1.79 ± 0.79
Globus Pallidus2.12 ± 0.33
Hypothalamus1.78 ± 1.03
Insula1.79 ± 0.74
Limbic Lobe2.07 ± 0.83
Mesencephalon1.92 ± 0.8
Myelencephalon1.82 ± 0.77
Occipital Lobe1.59 ± 0.6
Parietal Lobe1.63 ± 0.86
Pontine Tegmentum1.84 ± 0.75
Striatum1.93 ± 0.76
Subthalamus1.81 ± 0.71
Temporal Lobe1.79 ± 0.84
Thalamus1.63 ± 0.7
White Matter1.9 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TgnCBCerebellum1.77
1.85
TgnCTXCerebral cortex1.57
2.42
TgnHIPHippocampal region0.84
0.76
TgnHPFHippocampal formation0.82
0.7
TgnHYHypothalamus0.05
0.07
TgnLSXLateral septal complex0.45
0.66
TgnMBMidbrain0.42
0.59
TgnMYMedulla1.01
1.1
TgnOLFOlfactory bulb1.59
1.24
TgnPPons0.38
0.39
TgnPALPallidum0.29
0.26
TgnRHPRetrohippocampal region0.86
0.66
TgnsAMYStriatum-like amygdalar nuclei0.18
0.29
TgnSTRStriatum0.2
0.21
TgnSTRdStriatum dorsal region0.2
0.17
TgnSTRvStriatum ventral region0.11
0.06
TgnTHThalamus0.48
0.57
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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