AutismKB 2.0

Annotation Detail for TGFB1


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Basic Information Top
Gene Symbol:TGFB1 ( CED,DPD1,LAP,TGFB,TGFbeta )
Gene Full Name: transforming growth factor, beta 1
Band: 19q13.1
Quick LinksEntrez ID:7040; OMIM: 190180; Uniprot ID:TGFB1_HUMAN; ENSEMBL ID: ENSG00000105329; HGNC ID: 11766
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus7 / 56401212
neonate2 / 3109764
infant0 / 236200 
juvenile5 / 5555689
adult207 / 1939121106
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma20 / 82823241
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor11 / 26384541
glioma9 / 10688384
head and neck tumor26 / 136302190
kidney tumor7 / 68959101
leukemia23 / 95842239
liver tumor15 / 96359155
lung tumor3 / 10312729
lymphoma9 / 71755125
non-neoplasia5 / 9725051
normal173 / 336030751
ovarian tumor0 / 766820 
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor11 / 12494988
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood36 / 123478291
bone19 / 71655265
bone marrow4 / 4880181
brain29 / 110098926
cervix2 / 4817141
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye18 / 21105485
heart2 / 8962622
intestine9 / 23447238
kidney13 / 21177761
larynx1 / 2414541
liver15 / 20774372
lung17 / 33697450
lymph4 / 4427090
lymph node3 / 9161032
mammary gland11 / 15327171
mouth5 / 6705274
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta29 / 280825103
prostate8 / 18934542
salivary gland13 / 20155645
skin13 / 21057461
spleen10 / 53952185
stomach5 / 9661951
testis3 / 3304429
thymus0 / 811310 
thyroid4 / 4747384
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord2 / 13680146
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219766_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte4.6
AdrenalCortex4.85
Adrenalgland3.9
Amygdala4.8
Appendix4.65
AtrioventricularNode3.75
BDCA4+_DentriticCells5.35
Bonemarrow4.75
BronchialEpithelialCells4.5
CD105+_Endothelial4.7
CD14+_Monocytes5.05
CD19+_BCells(neg._sel.)5
CD33+_Myeloid6.05
CD34+10.5
CD4+_Tcells5.2
CD56+_NKCells5.7
CD71+_EarlyErythroid4.95
CD8+_Tcells5.2
CardiacMyocytes5.85
Caudatenucleus4.3
Cerebellum3.75
CerebellumPeduncles5.25
CiliaryGanglion4.6
CingulateCortex4.75
Colorectaladenocarcinoma4.65
DorsalRootGanglion3.65
FetalThyroid4.5
Fetalbrain4.75
Fetalliver4
Fetallung3.9
GlobusPallidus9
Heart5.8
Hypothalamus5.1
Kidney3.7
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.8
Liver6.05
Lung5.05
Lymphnode4.85
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)6.5
MedullaOblongata4.3
OccipitalLobe4.2
OlfactoryBulb3.65
Ovary3.05
Pancreas3.85
PancreaticIslet4.85
ParietalLobe4.85
Pituitary5.45
Placenta4.9
Pons5.1
PrefrontalCortex5.45
Prostate5.15
Salivarygland3.7
SkeletalMuscle6.7
Skin3.7
SmoothMuscle5.3
Spinalcord5.05
SubthalamicNucleus6.75
SuperiorCervicalGanglion6.6
TemporalLobe4.25
Testis4.1
TestisGermCell4.05
TestisIntersitial4.1
TestisLeydigCell11.15
TestisSeminiferousTubule4.15
Thalamus5.9
Thymus3.8
Thyroid5.65
Tongue5.5
Tonsil4.85
Trachea4.15
TrigeminalGanglion10.85
Uterus3.7
UterusCorpus4.15
WholeBlood5.15
Wholebrain4
colon4.6
pineal_day7.78
pineal_night6.28
retina5.75
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_651_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.21 ± 0.72
Basal Forebrain4.3 ± 0.49
Basal Part of Pons3.43 ± 0.63
Cerebellar Cortex3.46 ± 0.61
Cerebellar Nuclei4.68 ± 0.63
Claustrum4.36 ± 0.68
Epithalamus4.62 ± 0.55
Frontal Lobe3.8 ± 0.78
Globus Pallidus5.78 ± 0.59
Hypothalamus4.31 ± 0.96
Insula3.83 ± 0.7
Limbic Lobe3.67 ± 0.82
Mesencephalon4.26 ± 0.75
Myelencephalon4.02 ± 0.7
Occipital Lobe3.85 ± 0.76
Parietal Lobe3.93 ± 0.84
Pontine Tegmentum4.22 ± 0.74
Striatum4.42 ± 0.7
Subthalamus3.85 ± 0.4
Temporal Lobe3.93 ± 0.62
Thalamus4.09 ± 0.66
White Matter4.95 ± 0.51
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026375 27 59 85 LASPPSQGEVPPGPLPEAVLALYNSTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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