AutismKB 2.0

Annotation Detail for TGFB1I1


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Basic Information Top
Gene Symbol:TGFB1I1 ( ARA55,HIC-5,HIC5,TSC-5 )
Gene Full Name: transforming growth factor beta 1 induced transcript 1
Band: 16p11.2
Quick LinksEntrez ID:7041; OMIM: 602353; Uniprot ID:TGFI1_HUMAN; ENSEMBL ID: ENSG00000140682; HGNC ID: 11767
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus18 / 56401231
neonate8 / 31097257
infant2 / 2362084
juvenile2 / 5555635
adult114 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor3 / 17290173
gastrointestinal tumor4 / 11936933
germ cell tumor5 / 26384518
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal220 / 336030765
ovarian tumor8 / 76682104
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor28 / 125191223
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone6 / 7165583
bone marrow0 / 488010 
brain41 / 110098937
cervix2 / 4817141
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus5 / 20209247
eye13 / 21105461
heart3 / 8962633
intestine21 / 23447289
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth1 / 6705214
muscle14 / 107715129
nerve0 / 157680 
ovary17 / 102051166
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta36 / 280825128
prostate9 / 18934547
salivary gland0 / 201550 
skin11 / 21057452
spleen7 / 53952129
stomach10 / 96619103
testis8 / 33044224
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord8 / 13680584
uterus59 / 232878253
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209651_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.45
Adipocyte34.95
AdrenalCortex11.05
Adrenalgland18.3
Amygdala8.45
Appendix38.65
AtrioventricularNode6.2
BDCA4+_DentriticCells7.15
Bonemarrow8.2
BronchialEpithelialCells8.5
CD105+_Endothelial8.7
CD14+_Monocytes7.5
CD19+_BCells(neg._sel.)8.3
CD33+_Myeloid8.4
CD34+11.05
CD4+_Tcells7.8
CD56+_NKCells8.85
CD71+_EarlyErythroid7.9
CD8+_Tcells6.2
CardiacMyocytes91.5
Caudatenucleus7.5
Cerebellum6.9
CerebellumPeduncles9.55
CiliaryGanglion5.75
CingulateCortex8.65
Colorectaladenocarcinoma14
DorsalRootGanglion6.3
FetalThyroid22.55
Fetalbrain7.9
Fetalliver7.25
Fetallung58.35
GlobusPallidus6
Heart56.45
Hypothalamus9.25
Kidney15.5
Leukemia_chronicMyelogenousK-5627.55
Leukemia_promyelocytic-HL-607.15
Leukemialymphoblastic(MOLT-4)6.3
Liver10.95
Lung176.6
Lymphnode11.85
Lymphoma_burkitts(Daudi)10.5
Lymphoma_burkitts(Raji)11.45
MedullaOblongata7.5
OccipitalLobe7.35
OlfactoryBulb15.75
Ovary6.6
Pancreas7.05
PancreaticIslet9.05
ParietalLobe8.8
Pituitary9.25
Placenta60.85
Pons7.7
PrefrontalCortex10.85
Prostate196.95
Salivarygland6.7
SkeletalMuscle9.3
Skin6.3
SmoothMuscle237.25
Spinalcord9.1
SubthalamicNucleus7.4
SuperiorCervicalGanglion9.45
TemporalLobe7.7
Testis23.85
TestisGermCell9.45
TestisIntersitial7
TestisLeydigCell8.35
TestisSeminiferousTubule7.35
Thalamus8.6
Thymus6.85
Thyroid23.15
Tongue8.75
Tonsil8.05
Trachea14.95
TrigeminalGanglion8.15
Uterus594.75
UterusCorpus28.6
WholeBlood9.25
Wholebrain7.1
colon82.55
pineal_day9.8
pineal_night9.4
retina21.45
small_intestine73.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9453_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.83 ± 0.93
Basal Forebrain2.16 ± 0.26
Basal Part of Pons1.97 ± 0.53
Cerebellar Cortex2.18 ± 0.68
Cerebellar Nuclei2.62 ± 0.73
Claustrum3.13 ± 0.78
Epithalamus2.22 ± 0.76
Frontal Lobe2.2 ± 0.76
Globus Pallidus3.02 ± 0.69
Hypothalamus2.31 ± 0.83
Insula2.03 ± 0.51
Limbic Lobe2.28 ± 0.65
Mesencephalon2.49 ± 0.6
Myelencephalon2.41 ± 0.7
Occipital Lobe2.25 ± 0.65
Parietal Lobe2.35 ± 0.76
Pontine Tegmentum2.3 ± 0.75
Striatum2.66 ± 0.63
Subthalamus2.52 ± 0.66
Temporal Lobe2.24 ± 0.62
Thalamus2.36 ± 0.58
White Matter2.76 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tgfb1i1CBCerebellum0.36
0.9
Tgfb1i1CTXCerebral cortex0.43
0.63
Tgfb1i1HIPHippocampal region0.34
0.65
Tgfb1i1HPFHippocampal formation0.64
0.82
Tgfb1i1HYHypothalamus1.62
5.14
Tgfb1i1LSXLateral septal complex0.56
0.9
Tgfb1i1MBMidbrain0.55
1.75
Tgfb1i1MYMedulla1.52
3.56
Tgfb1i1OLFOlfactory bulb1.45
3.47
Tgfb1i1PPons1.29
4.71
Tgfb1i1PALPallidum0.38
0.57
Tgfb1i1RHPRetrohippocampal region1.35
1.16
Tgfb1i1sAMYStriatum-like amygdalar nuclei0
0
Tgfb1i1STRStriatum0.19
0.33
Tgfb1i1STRdStriatum dorsal region0.08
0.11
Tgfb1i1STRvStriatum ventral region0.37
0.79
Tgfb1i1THThalamus0.32
0.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00484248 20 209 228 GLCGSCNKPIAGQVVTALGR Peptide Atlas
TGFI1_HUMAN_148 21 148 168 ASATSATLELDRLMASLSDFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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