Annotation Detail for THBS3
Basic Information Top
| Gene Symbol: | THBS3 ( MGC119564,MGC119565,TSP3 ) |
|---|---|
| Gene Full Name: | thrombospondin 3 |
| Band: | 1q22 |
| Quick Links | Entrez ID:7059; OMIM: 188062; Uniprot ID:TSP3_HUMAN; ENSEMBL ID: ENSG00000169231; HGNC ID: 11787 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.169875
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 6 / 70761 | 84 |  |
| blastocyst | 3 / 62319 | 48 |  |
| fetus | 27 / 564012 | 47 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 125 / 1939121 | 64 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 10 / 82823 | 120 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 19 / 119369 | 159 | |
| germ cell tumor | 44 / 263845 | 166 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 4 / 71755 | 55 | |
| non-neoplasia | 13 / 97250 | 133 | |
| normal | 144 / 3360307 | 42 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 4 / 40015 | 99 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 31 / 1100989 | 28 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 21 / 149255 | 140 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 17 / 215722 | 78 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 6 / 89626 | 66 | |
| intestine | 9 / 234472 | 38 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 36 / 336974 | 106 | |
| lymph | 4 / 44270 | 90 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 17 / 96619 | 175 | |
| testis | 45 / 330442 | 136 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 18 / 232878 | 77 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209561_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.2 | |
| Adipocyte | 4.95 | |
| AdrenalCortex | 5.55 | |
| Adrenalgland | 4.25 | |
| Amygdala | 5.1 | |
| Appendix | 6.1 | |
| AtrioventricularNode | 4 | |
| BDCA4+_DentriticCells | 5.55 | |
| Bonemarrow | 4.85 | |
| BronchialEpithelialCells | 4.8 | |
| CD105+_Endothelial | 5 | |
| CD14+_Monocytes | 5.3 | |
| CD19+_BCells(neg._sel.) | 5.35 | |
| CD33+_Myeloid | 6.5 | |
| CD34+ | 8.95 | |
| CD4+_Tcells | 7 | |
| CD56+_NKCells | 6.1 | |
| CD71+_EarlyErythroid | 4.6 | |
| CD8+_Tcells | 4.95 | |
| CardiacMyocytes | 6.2 | |
| Caudatenucleus | 4.45 | |
| Cerebellum | 4 | |
| CerebellumPeduncles | 5.6 | |
| CiliaryGanglion | 3.55 | |
| CingulateCortex | 5.1 | |
| Colorectaladenocarcinoma | 5 | |
| DorsalRootGanglion | 3.8 | |
| FetalThyroid | 5.4 | |
| Fetalbrain | 5 | |
| Fetalliver | 4.3 | |
| Fetallung | 4.3 | |
| GlobusPallidus | 3.7 | |
| Heart | 6.35 | |
| Hypothalamus | 5.3 | |
| Kidney | 4.1 | |
| Leukemia_chronicMyelogenousK-562 | 4.5 | |
| Leukemia_promyelocytic-HL-60 | 4.4 | |
| Leukemialymphoblastic(MOLT-4) | 3.95 | |
| Liver | 6.65 | |
| Lung | 5.6 | |
| Lymphnode | 4.35 | |
| Lymphoma_burkitts(Daudi) | 6.3 | |
| Lymphoma_burkitts(Raji) | 7.1 | |
| MedullaOblongata | 4.55 | |
| OccipitalLobe | 4.4 | |
| OlfactoryBulb | 3.9 | |
| Ovary | 3.35 | |
| Pancreas | 4 | |
| PancreaticIslet | 5.3 | |
| ParietalLobe | 5.25 | |
| Pituitary | 5.75 | |
| Placenta | 5.6 | |
| Pons | 4.75 | |
| PrefrontalCortex | 6.15 | |
| Prostate | 5.95 | |
| Salivarygland | 4 | |
| SkeletalMuscle | 6.05 | |
| Skin | 3.85 | |
| SmoothMuscle | 5.7 | |
| Spinalcord | 5.3 | |
| SubthalamicNucleus | 4.55 | |
| SuperiorCervicalGanglion | 5.6 | |
| TemporalLobe | 4.55 | |
| Testis | 31.8 | |
| TestisGermCell | 20.2 | |
| TestisIntersitial | 16.3 | |
| TestisLeydigCell | 5.4 | |
| TestisSeminiferousTubule | 15.6 | |
| Thalamus | 5.05 | |
| Thymus | 4 | |
| Thyroid | 6.65 | |
| Tongue | 5.05 | |
| Tonsil | 4.9 | |
| Trachea | 4.2 | |
| TrigeminalGanglion | 5 | |
| Uterus | 14.5 | |
| UterusCorpus | 4.45 | |
| WholeBlood | 5.4 | |
| Wholebrain | 4.15 | |
| colon | 5 | |
| pineal_day | 6.2 | |
| pineal_night | 6.06 | |
| retina | 6.075 | |
| small_intestine | 4.8 | |
- Probe name: CUST_5518_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.01 ± 0.65 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.64 ± 0.27 | |
| Basal Part of Pons | 2.72 ± 0.62 | |
| Cerebellar Cortex | 2.91 ± 0.62 | |
| Cerebellar Nuclei | 2.67 ± 0.52 | |
| Claustrum | 3.01 ± 0.55 | |
| Epithalamus | 2.93 ± 0.52 | |
| Frontal Lobe | 2.97 ± 0.63 | |
| Globus Pallidus | 2.33 ± 0.66 | |
| Hypothalamus | 3.02 ± 0.57 | |
| Insula | 3.08 ± 0.4 | |
| Limbic Lobe | 3.02 ± 0.66 | |
| Mesencephalon | 2.9 ± 0.74 | |
| Myelencephalon | 2.92 ± 0.57 | |
| Occipital Lobe | 2.78 ± 0.83 | |
| Parietal Lobe | 2.89 ± 0.55 | |
| Pontine Tegmentum | 2.99 ± 0.56 | |
| Striatum | 3.06 ± 0.73 | |
| Subthalamus | 3.07 ± 0.29 | |
| Temporal Lobe | 3.13 ± 0.59 | |
| Thalamus | 2.72 ± 0.6 | |
| White Matter | 2.64 ± 0.61 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Thbs3 | CB | Cerebellum | 0.99 | |
| 1.21 | | |||
| Thbs3 | CTX | Cerebral cortex | 8.8 | |
| 5.73 | | |||
| Thbs3 | HIP | Hippocampal region | 30.74 | |
| 46.43 | | |||
| Thbs3 | HPF | Hippocampal formation | 23.22 | |
| 29.09 | | |||
| Thbs3 | HY | Hypothalamus | 7.16 | |
| 4.91 | | |||
| Thbs3 | LSX | Lateral septal complex | 18.11 | |
| 11.84 | | |||
| Thbs3 | MB | Midbrain | 1.05 | |
| 0.91 | | |||
| Thbs3 | MY | Medulla | 4.99 | |
| 5.37 | | |||
| Thbs3 | OLF | Olfactory bulb | 13.39 | |
| 8.82 | | |||
| Thbs3 | P | Pons | 1.83 | |
| 1.86 | | |||
| Thbs3 | PAL | Pallidum | 7.59 | |
| 5.89 | | |||
| Thbs3 | RHP | Retrohippocampal region | 11.91 | |
| 9.19 | | |||
| Thbs3 | sAMY | Striatum-like amygdalar nuclei | 35.16 | |
| 25.38 | | |||
| Thbs3 | STR | Striatum | 19.03 | |
| 12.27 | | |||
| Thbs3 | STRd | Striatum dorsal region | 19.16 | |
| 12.35 | | |||
| Thbs3 | STRv | Striatum ventral region | 10.45 | |
| 5.67 | | |||
| Thbs3 | TH | Thalamus | 2.11 | |
| 2.2 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00489906 | 7 | 804 | 810 | FYVVMWK | Peptide Atlas |