AutismKB 2.0

Annotation Detail for TSPO


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Basic Information Top
Gene Symbol:TSPO ( BPBS,BZRP,DBI,IBP,MBR,PBR,PBS,PKBS,PTBR,mDRC,pk18 )
Gene Full Name: translocator protein (18kDa)
Band: 22q13.2
Quick LinksEntrez ID:706; OMIM: 109610; Uniprot ID:TSPOA_HUMAN; ENSEMBL ID: ENSG00000100300; HGNC ID: 1158
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus45 / 56401279
neonate2 / 3109764
infant1 / 2362042
juvenile1 / 5555617
adult172 / 193912188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor4 / 34366116
chondrosarcoma11 / 82823132
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor29 / 119369242
germ cell tumor2 / 2638457
glioma18 / 106883168
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia17 / 95842177
liver tumor4 / 9635941
lung tumor13 / 103127126
lymphoma5 / 7175569
non-neoplasia6 / 9725061
normal206 / 336030761
ovarian tumor5 / 7668265
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer7 / 10268068
retinoblastoma0 / 463560 
skin tumor16 / 124949128
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites16 / 40015399
bladder2 / 2975767
blood13 / 123478105
bone18 / 71655251
bone marrow2 / 4880140
brain29 / 110098926
cervix7 / 48171145
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye20 / 21105494
heart8 / 8962689
intestine28 / 234472119
kidney15 / 21177770
larynx2 / 2414582
liver9 / 20774343
lung41 / 336974121
lymph4 / 4427090
lymph node16 / 91610174
mammary gland13 / 15327184
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary7 / 10205168
pancreas20 / 21481293
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta19 / 28082567
prostate20 / 189345105
salivary gland4 / 20155198
skin36 / 210574170
spleen3 / 5395255
stomach11 / 96619113
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus16 / 23287868
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202096_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts15
Adipocyte275.6
AdrenalCortex14.5
Adrenalgland26.2
Amygdala16.75
Appendix24.55
AtrioventricularNode12.4
BDCA4+_DentriticCells359
Bonemarrow543.35
BronchialEpithelialCells962.5
CD105+_Endothelial435.7
CD14+_Monocytes3255.9
CD19+_BCells(neg._sel.)262.85
CD33+_Myeloid3859.35
CD34+644.6
CD4+_Tcells147.35
CD56+_NKCells308.2
CD71+_EarlyErythroid387.05
CD8+_Tcells74.9
CardiacMyocytes248.7
Caudatenucleus10.35
Cerebellum9.3
CerebellumPeduncles14.8
CiliaryGanglion7.85
CingulateCortex11.75
Colorectaladenocarcinoma119.95
DorsalRootGanglion9.4
FetalThyroid38
Fetalbrain35.05
Fetalliver9.3
Fetallung105.25
GlobusPallidus7.95
Heart680.95
Hypothalamus16.6
Kidney10.5
Leukemia_chronicMyelogenousK-56226.55
Leukemia_promyelocytic-HL-6038.2
Leukemialymphoblastic(MOLT-4)9
Liver54.35
Lung1466.8
Lymphnode29.6
Lymphoma_burkitts(Daudi)13.9
Lymphoma_burkitts(Raji)16.2
MedullaOblongata10.5
OccipitalLobe10.45
OlfactoryBulb14.3
Ovary8.25
Pancreas49.3
PancreaticIslet30.95
ParietalLobe11.95
Pituitary15.1
Placenta41.55
Pons10.85
PrefrontalCortex16.7
Prostate944.65
Salivarygland10.6
SkeletalMuscle12.65
Skin64.3
SmoothMuscle464.3
Spinalcord20.05
SubthalamicNucleus9.35
SuperiorCervicalGanglion12.7
TemporalLobe10.45
Testis10.6
TestisGermCell9.45
TestisIntersitial9.65
TestisLeydigCell11.25
TestisSeminiferousTubule9.95
Thalamus12.15
Thymus33.35
Thyroid182.75
Tongue325.05
Tonsil63.8
Trachea24.15
TrigeminalGanglion14.5
Uterus76.3
UterusCorpus19.3
WholeBlood1092.1
Wholebrain16.9
colon246.55
pineal_day15.3
pineal_night14.02
retina75.025
small_intestine109.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11234_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.52 ± 0.6
Basal Forebrain5.45 ± 0.4
Basal Part of Pons5.39 ± 0.44
Cerebellar Cortex5.06 ± 0.39
Cerebellar Nuclei5.48 ± 0.41
Claustrum5.97 ± 0.55
Epithalamus4.8 ± 0.47
Frontal Lobe5.44 ± 0.53
Globus Pallidus5.78 ± 0.44
Hypothalamus5.58 ± 0.42
Insula5.21 ± 0.48
Limbic Lobe5.46 ± 0.52
Mesencephalon5.46 ± 0.5
Myelencephalon5.43 ± 0.5
Occipital Lobe5.37 ± 0.45
Parietal Lobe5.37 ± 0.49
Pontine Tegmentum5.37 ± 0.42
Striatum5.54 ± 0.5
Subthalamus5.35 ± 0.39
Temporal Lobe5.4 ± 0.54
Thalamus5.41 ± 0.44
White Matter5.72 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TspoCBCerebellum9.1
7.38
TspoCTXCerebral cortex6.82
4.08
TspoHIPHippocampal region6.95
3.72
TspoHPFHippocampal formation6.53
3.76
TspoHYHypothalamus6.4
3.93
TspoLSXLateral septal complex2.06
3.44
TspoMBMidbrain3.5
3.15
TspoMYMedulla8.57
6.99
TspoOLFOlfactory bulb12.16
7.38
TspoPPons6.41
4.9
TspoPALPallidum2.99
2.52
TspoRHPRetrohippocampal region5.98
3.84
TsposAMYStriatum-like amygdalar nuclei4.98
2.97
TspoSTRStriatum3.25
1.84
TspoSTRdStriatum dorsal region1.46
0.87
TspoSTRvStriatum ventral region7.75
3.38
TspoTHThalamus6.45
3.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009300 23 2 24 APPWVPAMGFTLAPSLGCFVGSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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