Annotation Detail for THBS4
Basic Information Top
| Gene Symbol: | THBS4 ( TSP4 ) |
|---|---|
| Gene Full Name: | thrombospondin 4 |
| Band: | 5q14.1 |
| Quick Links | Entrez ID:7060; OMIM: 600715; Uniprot ID:TSP4_HUMAN; ENSEMBL ID: ENSG00000113296; HGNC ID: 11788 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.211426
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 27 / 564012 | 47 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 57 / 1939121 | 29 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 6 / 82823 | 72 |  |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 10 / 119369 | 83 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 11 / 97250 | 113 | |
| normal | 74 / 3360307 | 22 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 7 / 104616 | 66 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 11 / 102680 | 107 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 13 / 1100989 | 11 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 14 / 149255 | 93 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 16 / 211054 | 75 | |
| heart | 4 / 89626 | 44 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 1 / 24145 | 41 | |
| liver | 0 / 207743 | 0 | |
| lung | 5 / 336974 | 14 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 12 / 67052 | 178 | |
| muscle | 7 / 107715 | 64 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 12 / 189345 | 63 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 10 / 96619 | 103 | |
| testis | 12 / 330442 | 36 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204776_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6 | |
| Adipocyte | 6.55 | |
| AdrenalCortex | 6.7 | |
| Adrenalgland | 5.45 | |
| Amygdala | 7.95 | |
| Appendix | 6.55 | |
| AtrioventricularNode | 4.95 | |
| BDCA4+_DentriticCells | 5.25 | |
| Bonemarrow | 6.45 | |
| BronchialEpithelialCells | 5.6 | |
| CD105+_Endothelial | 4.95 | |
| CD14+_Monocytes | 5.35 | |
| CD19+_BCells(neg._sel.) | 6.2 | |
| CD33+_Myeloid | 7.65 | |
| CD34+ | 10.5 | |
| CD4+_Tcells | 5.3 | |
| CD56+_NKCells | 5.8 | |
| CD71+_EarlyErythroid | 5 | |
| CD8+_Tcells | 4.7 | |
| CardiacMyocytes | 8.1 | |
| Caudatenucleus | 10.55 | |
| Cerebellum | 5.3 | |
| CerebellumPeduncles | 7.4 | |
| CiliaryGanglion | 8.8 | |
| CingulateCortex | 7.15 | |
| Colorectaladenocarcinoma | 5.65 | |
| DorsalRootGanglion | 7.95 | |
| FetalThyroid | 7.4 | |
| Fetalbrain | 6.5 | |
| Fetalliver | 5.65 | |
| Fetallung | 5.35 | |
| GlobusPallidus | 8.1 | |
| Heart | 37.9 | |
| Hypothalamus | 13.1 | |
| Kidney | 5.25 | |
| Leukemia_chronicMyelogenousK-562 | 5.8 | |
| Leukemia_promyelocytic-HL-60 | 5.65 | |
| Leukemialymphoblastic(MOLT-4) | 5.15 | |
| Liver | 8.45 | |
| Lung | 7.05 | |
| Lymphnode | 5.65 | |
| Lymphoma_burkitts(Daudi) | 8.9 | |
| Lymphoma_burkitts(Raji) | 8.8 | |
| MedullaOblongata | 6.1 | |
| OccipitalLobe | 6.2 | |
| OlfactoryBulb | 5.65 | |
| Ovary | 4.35 | |
| Pancreas | 5.2 | |
| PancreaticIslet | 8.4 | |
| ParietalLobe | 6.8 | |
| Pituitary | 101.75 | |
| Placenta | 5.9 | |
| Pons | 6.15 | |
| PrefrontalCortex | 9.25 | |
| Prostate | 8.3 | |
| Salivarygland | 6.6 | |
| SkeletalMuscle | 13 | |
| Skin | 5.1 | |
| SmoothMuscle | 5.7 | |
| Spinalcord | 15.6 | |
| SubthalamicNucleus | 8.25 | |
| SuperiorCervicalGanglion | 8.4 | |
| TemporalLobe | 7.4 | |
| Testis | 10.55 | |
| TestisGermCell | 10.05 | |
| TestisIntersitial | 10.8 | |
| TestisLeydigCell | 7.6 | |
| TestisSeminiferousTubule | 9.7 | |
| Thalamus | 11.45 | |
| Thymus | 5.25 | |
| Thyroid | 8.15 | |
| Tongue | 48.7 | |
| Tonsil | 6.25 | |
| Trachea | 10.45 | |
| TrigeminalGanglion | 7.45 | |
| Uterus | 7.05 | |
| UterusCorpus | 6 | |
| WholeBlood | 5.5 | |
| Wholebrain | 6.45 | |
| colon | 6.6 | |
| pineal_day | 661.72 |  |
| pineal_night | 642.66 | |
| retina | 22.9 | |
| small_intestine | 6.55 | |
- Probe name: CUST_5497_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.64 ± 0.5 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.12 ± 0.49 | |
| Basal Part of Pons | 4.73 ± 0.59 | |
| Cerebellar Cortex | 4.29 ± 0.42 | |
| Cerebellar Nuclei | 4.5 ± 0.39 | |
| Claustrum | 4 ± 0.88 | |
| Epithalamus | 5.16 ± 0.63 | |
| Frontal Lobe | 5.02 ± 0.62 | |
| Globus Pallidus | 6.35 ± 0.45 | |
| Hypothalamus | 5.43 ± 0.44 | |
| Insula | 5.06 ± 0.37 | |
| Limbic Lobe | 4.52 ± 0.65 | |
| Mesencephalon | 5.05 ± 0.79 | |
| Myelencephalon | 4.94 ± 0.68 | |
| Occipital Lobe | 4.91 ± 0.64 | |
| Parietal Lobe | 4.81 ± 0.67 | |
| Pontine Tegmentum | 5.05 ± 0.58 | |
| Striatum | 5.57 ± 0.54 | |
| Subthalamus | 4.86 ± 0.66 | |
| Temporal Lobe | 4.72 ± 0.56 | |
| Thalamus | 5.41 ± 0.64 | |
| White Matter | 3.14 ± 1.04 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Thbs4 | CB | Cerebellum | 3.65 | |
| 4.6 | | |||
| Thbs4 | CTX | Cerebral cortex | 3.39 | |
| 3.75 | | |||
| Thbs4 | HIP | Hippocampal region | 10.66 | |
| 13.2 | | |||
| Thbs4 | HPF | Hippocampal formation | 9.28 | |
| 10.66 | | |||
| Thbs4 | HY | Hypothalamus | 0.38 | |
| 0.34 | | |||
| Thbs4 | LSX | Lateral septal complex | 17.24 | |
| 25.12 | | |||
| Thbs4 | MB | Midbrain | 1.12 | |
| 1.39 | | |||
| Thbs4 | MY | Medulla | 5.12 | |
| 5.7 | | |||
| Thbs4 | OLF | Olfactory bulb | 4.3 | |
| 4.19 | | |||
| Thbs4 | P | Pons | 2.94 | |
| 3.51 | | |||
| Thbs4 | PAL | Pallidum | 1.2 | |
| 1.13 | | |||
| Thbs4 | RHP | Retrohippocampal region | 6.66 | |
| 6.74 | | |||
| Thbs4 | sAMY | Striatum-like amygdalar nuclei | 2.81 | |
| 2.45 | | |||
| Thbs4 | STR | Striatum | 5.56 | |
| 7.08 | | |||
| Thbs4 | STRd | Striatum dorsal region | 5.5 | |
| 7.32 | | |||
| Thbs4 | STRv | Striatum ventral region | 2.6 | |
| 2 | | |||
| Thbs4 | TH | Thalamus | 1.06 | |
| 1.11 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00060782 | 22 | 350 | 371 | CDACPVGFTGPMVQGVGISFAK | Peptide Atlas |